YRC Public Data Repository - Protein Structure Prediction

Protein:	RNH2_CAMJR
Organism:	Campylobacter jejuni RM1221
Length:	191 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNH2_CAMJR.

Description	E-value	Query Range	Subject Range
RNH2_BACCR - Ribonuclease HII OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NCIMB 9373...	259.0	[0..6]	[191..62]
RNH2_PSEA8 - Ribonuclease HII OS=Pseudomonas aeruginosa (strain LESB58) GN=rnhB PE=3 SV=1 gi\|107103156 - gi\|107103156\|ref\|ZP_01367074.1\| hypothetical protein PaerPA_01004225 [Pseudomonas aeruginosa PACS2] gi\|84319622, gi\|... - gi\|84319622\|ref\|ZP_00968016.1\| COG0164: Ribonuclease HII [Pseudomonas aeruginosa C3719], gi\|25423655... gi\|84325648, gi\|... - gi\|84325648\|ref\|ZP_00973682.1\| COG0164: Ribonuclease HII [Pseudomonas aeruginosa 2192], gi\|254242340...	257.0	[0..16]	[191..12]
RNH2_PSEAE - Ribonuclease HII OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN=... RNH2_PSEAE - Ribonuclease HII OS=Pseudomonas aeruginosa GN=rnhB PE=3 SV=1	256.0	[0..16]	[191..12]
RNH2_PSEA7 - Ribonuclease HII OS=Pseudomonas aeruginosa (strain PA7) GN=rnhB PE=3 SV=1	256.0	[0..16]	[191..12]
RNH2_PSEAB - Ribonuclease HII OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=rnhB PE=3 SV=1	255.0	[0..16]	[191..12]
gi\|49082728 - gi\|49082728\|gb\|AAT50764.1\| PA3642 [synthetic construct]	255.0	[0..16]	[191..12]
gi\|95930749, gi\|... - gi\|95930749\|ref\|ZP_01313482.1\| Ribonuclease H [Desulfuromonas acetoxidans DSM 684], gi\|95133229\|gb\|E...	253.0	[0..5]	[188..15]
RNH2_PARUW - Ribonuclease HII OS=Protochlamydia amoebophila (strain UWE25) GN=rnhB PE=3 SV=1	252.0	[0..4]	[191..17]
RNH2_VIBPA - Ribonuclease HII OS=Vibrio parahaemolyticus GN=rnhB PE=3 SV=1 RNH2_VIBPA - Ribonuclease HII OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=rnhB PE=3 SV=1	251.0	[0..10]	[191..18]
gi\|91223487, gi\|... - gi\|91223487\|ref\|ZP_01258752.1\| ribonuclease HII [Vibrio alginolyticus 12G01], gi\|91191573\|gb\|EAS7783...	251.0	[0..10]	[191..18]

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Predicted Domain #1

Region A:
Residues: [1-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKTLFDTKEL LNEFDINLIG IDEAGRGALA GPMMMAACKL NKQLDGLCDS KKLSEKKREE  60
   61 LYEIIIKNSN YLILAFSSEQ IDALGLSTCL KKGLKLIKKH FKTENNFLYD GNTNLGINGI 120
  121 KTQIKADTSI LQVSAASILA KVSKDRVMNF LAKDFPCYEF EKNKAYGTKA HKEFIAKFGI 180
  181 CKLHRKSFKL L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	60.39794
Match:	2etjA
Description:	Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribonuclease activity	3.91517707500372	bayes_pls_golite062009
endoribonuclease activity	3.00008907756136	bayes_pls_golite062009
ribonuclease H activity	2.37346218921366	bayes_pls_golite062009
hydrolase activity	2.30893115816458	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	2.26022264830742	bayes_pls_golite062009
nuclease activity	1.81796593394339	bayes_pls_golite062009
endonuclease activity	1.79009816048707	bayes_pls_golite062009
catalytic activity	1.62277843225829	bayes_pls_golite062009
exoribonuclease activity	1.48827607538468	bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters	1.34153791988846	bayes_pls_golite062009
3'-5'-exoribonuclease activity	0.8085201347205	bayes_pls_golite062009
exonuclease activity	0.39213900591465	bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters	0.13187450705887	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: