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View Structure Prediction Details

Protein: AMD1
Organism: Homo sapiens
Length: 334 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AMD1.

Description E-value Query
Range		 Subject
Range
DCAM_BOVIN - S-adenosylmethionine decarboxylase proenzyme OS=Bos taurus GN=AMD1 PE=1 SV=1
 0.0 [1..334] [1..334]
DCAM_MESAU - S-adenosylmethionine decarboxylase proenzyme OS=Mesocricetus auratus GN=AMD1 PE=2 SV=1
 0.0 [1..334] [1..334]
gi|29726499, gi|... - gi|29726499|pdb|1MSV|B Chain B, The S68a S-Adenosylmethionine Decarboxylase Proenzyme Processing Mut...
 0.0 [1..334] [1..334]
DCAM1_MOUSE - S-adenosylmethionine decarboxylase proenzyme 1 OS=Mus musculus GN=Amd1 PE=1 SV=1
gi|55250462 - gb|AAH85966.1| Unknown (protein for MGC:97920) [Xenopus laevis]
 0.0 [1..334] [1..334]
DCAM2_MUSSP - S-adenosylmethionine decarboxylase proenzyme 2 OS=Mus spretus GN=Amd2 PE=3 SV=1
 0.0 [1..334] [1..334]
DCAM_RAT - S-adenosylmethionine decarboxylase proenzyme OS=Rattus norvegicus GN=Amd1 PE=2 SV=3
 0.0 [1..332] [1..332]

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Predicted Domain #1
Region A:
Residues: [1-334] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAAHFFEGT EKLLEVWFSR QQPDANQGSG DLRTIPRSEW DILLKDVQCS IISVTKTDKQ  60
   61 EAYVLSESSM FVSKRRFILK TCGTTLLLKA LVPLLKLARD YSGFDSIQSF FYSRKNFMKP 120
  121 SHQGYPHRNF QEEIEFLNAI FPNGAAYCMG RMNSDCWYLY TLDFPESRVI SQPDQTLEIL 180
  181 MSELDPAVMD QFYMKDGVTA KDVTRESGIR DLIPGSVIDA TMFNPCGYSM NGMKSDGTYW 240
  241 TIHITPEPEF SYVSFETNLS QTSYDDLIRK VVEVFKPGKF VTTLFVNQSS KCRTVLASPQ 300
  301 KIEGFKRLDC QSAMFNDYNF VFTSFAKKQQ QQQS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 151.0
Match: 1msvA
Description: S-adenosylmethionine decarboxylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
adenosylmethionine decarboxylase activity 6.97190143843809 bayes_pls_golite062009
carbon-carbon lyase activity 2.68228786608236 bayes_pls_golite062009
carboxy-lyase activity 1.55250570844159 bayes_pls_golite062009
binding 1.4725833406744 bayes_pls_golite062009
catalytic activity 1.25843830926101 bayes_pls_golite062009
lyase activity 0.834955527171148 bayes_pls_golite062009
protein binding 0.443666756110255 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle