YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11353793
Organism:	Neisseria meningitidis
Length:	269 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11353793.

Description	E-value	Query Range	Subject Range
gi\|2935421 - gi\|2935421\|gb\|AAC25987.1\| adaptive response regulatory protein [Pseudoalteromonas sp. S9]	266.0	[0..3]	[266..113]
gi\|59801373, gi\|... - gi\|59801373\|ref\|YP_208085.1\| putative methylated-DNA-protein-cysteine methyltransferase [Neisseria g...	249.0	[0..1]	[269..21]
gi\|77459163, gi\|... - gi\|77459163\|ref\|YP_348669.1\| AraC family transcriptional regulator [Pseudomonas fluorescens Pf0-1], ...	243.0	[0..2]	[261..113]
gi\|11353982 - pir\|\|C81869 probable methylated-DNA-protein-cysteine methyltransferase NMA1728 [imported] - Neisseri... gi\|7380369, gi\|2... - gi\|7380369\|emb\|CAB84956.1\| putative methylated-DNA-protein-cysteine methyltransferase [Neisseria men...	242.0	[0..1]	[269..21]
gi\|186467753, gi... - gi\|23130248\|ref\|ZP_00112065.1\| COG2169: Adenosine deaminase [Nostoc punctiforme PCC 73102], gi\|18668...	242.0	[0..9]	[260..123]
gi\|94492256, gi\|... - gi\|94492256\|ref\|ZP_01299464.1\| hypothetical protein CburD_01000586 [Coxiella burnetii Dugway 7E9-12]...	242.0	[0..2]	[261..110]
gi\|148510043, gi... - gi\|82738984\|ref\|ZP_00901803.1\| Methylated-DNA-(protein)-cysteine S-methyltransferase [Pseudomonas pu...	237.0	[0..4]	[260..108]
gi\|167054339, gi... - gi\|167426650\|ref\|ZP_02318403.1\| ada regulatory protein [Yersinia pestis biovar Mediaevalis str. K197... gi\|229706633, gi... - gi\|229836185\|ref\|ZP_04456353.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis ... gi\|166962740, gi... - gi\|167418746\|ref\|ZP_02310499.1\| ada regulatory protein [Yersinia pestis biovar Orientalis str. MG05-... gi\|229839921, gi... - gi\|229839921\|ref\|ZP_04460080.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis ... gi\|229690313, gi... - gi\|229842003\|ref\|ZP_04462158.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis ... gi\|167468390 - gi\|167468390\|ref\|ZP_02333094.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis ... gi\|165915752, gi... - gi\|89103921\|ref\|ZP_01176481.1\| COG2169: Adenosine deaminase [Yersinia pestis biovar Orientalis str. ... gi\|22123991, gi\|... - gi\|22123991\|ref\|NP_667414.1\| O6-methylguanine-DNA methyltransferase; transcription activator/repress... gi\|25286162 - pir\|\|AH0009 methylated-DNA-[protein]-cysteine S-methyltransferase (EC 2.1.1.63) [imported] - Yersini... gi\|15978185, gi\|... - gi\|218927291\|ref\|YP_002345166.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis... gi\|108813939, gi... - gi\|229904468\|ref\|ZP_04519579.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis ... gi\|45434791, gi\|... - gi\|45439936\|ref\|NP_991475.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis bio... gi\|108809462, gi... - gi\|108809462\|ref\|YP_653378.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis An... gi\|166011470, gi... - gi\|166011470\|ref\|ZP_02232368.1\| ada regulatory protein [Yersinia pestis biovar Antiqua str. E1979001... gi\|165926103, gi... - gi\|165926103\|ref\|ZP_02221935.1\| ada regulatory protein [Yersinia pestis biovar Orientalis str. F1991... gi\|167399417, gi... - gi\|167399417\|ref\|ZP_02304941.1\| ada regulatory protein [Yersinia pestis biovar Antiqua str. UG05-045... gi\|166205146, gi... - gi\|166213744\|ref\|ZP_02239779.1\| ada regulatory protein [Yersinia pestis biovar Antiqua str. B4200300... gi\|150260866, gi... - gi\|150260866\|ref\|ZP_01917594.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis ... gi\|145212770, gi... - gi\|145601074\|ref\|YP_001165150.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pestis...	237.0	[0..9]	[266..117]
gi\|23347159, gi\|... - gi\|23501273\|ref\|NP_697400.1\| ada regulatory protein [Brucella suis 1330], gi\|23347159\|gb\|AAN29315.1\|...	236.0	[0..9]	[261..129]
gi\|68345072, gi\|... - gi\|70730773\|ref\|YP_260514.1\| ADA regulatory protein [Pseudomonas fluorescens Pf-5], gi\|68345072\|gb\|A...	236.0	[0..9]	[262..124]

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Predicted Domain #1

Region A:
Residues: [1-89]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAKIGDFAVK SMIGIRSKQM ITLPSLNNLP SKWDEIRHWL ESRVFECGVM PHPNLTECEA  60
   61 KQFERDFWDN IGCAPEEYVR IRRAIRLLE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	8.09691
Match:	1d5yA
Description:	Rob transcription factor, N-terminal domain; Rob transcription factor, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.76956337706487	bayes_pls_golite062009
DNA binding	1.58100039759954	bayes_pls_golite062009
nucleic acid binding	1.46839493313894	bayes_pls_golite062009
binding	1.095333525217	bayes_pls_golite062009
transcription factor activity	1.0707787742149	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [90-269]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ARYPDSLNEL VCAAIATPLG EMLAVFGSRG LCLLEFVGQK HLEQEIAAVQ KALRGRFVFR  60
   61 EDERTQLLRQ ELDLYFKGRL KTFATPLEQI GTEFQKQAWD ALLAIPYGET RSYKEQAQRL 120
  121 GNPKAVRAVA AANGQNKVSI LIPCHRVIGS DGKLTGYAGG LNRKQFLLAL EHGEVQTALF 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.30103
Match:	1sfeA
Description:	ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methylated-DNA-[protein]-cysteine S-methyltransferase activity	3.9938943760254	bayes_pls_golite062009
S-methyltransferase activity	2.96219931728042	bayes_pls_golite062009
catalytic activity	2.27882522649583	bayes_pls_golite062009
methyltransferase activity	1.63681159093596	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.6341981985862	bayes_pls_golite062009
transferase activity	1.42883081715544	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: