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View Structure Prediction Details

Protein: VSR7_ARATH
Organism: Arabidopsis thaliana
Length: 625 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for VSR7_ARATH.

Description E-value Query
Range
Subject
Range
gi|23198374, gi|... - gi|23198374|gb|AAN15714.1| vacuolar sorting receptor-like protein [Arabidopsis thaliana], gi|2253093...
473.0 [0..1] [625..1]

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Predicted Domain #1
Region A:
Residues: [1-70]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLVNGRASL TFLLAALTII AMVVEARFVV EKESISVLNP EEMRSKHDGS IANFGLPDYG  60
   61 GFLIGSVVYP 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [71-187]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DSKTDGCSAF GKTFKPKFPR PTILLLDRGG CYFALKAWHA QQAGAAAVLV ADNVDEPLLT  60
   61 MDSPEESKDA DGFIEKLTIP SVLIDKSFGD DLRQGFQKGK NIVIKLDWRE SVPHPDK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.154902
Match: 1xf1A
Description: Structure of C5a peptidase- a key virulence factor from Streptococcus
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [188-558]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVEYELWTNS NDECGARCDE QMDFVKNFKG HAQILEKGGY TAFTPHYITW FCPFQFINSP  60
   61 HCKSQCINHG RYCAPDPEDN FREGYEGKDV VLENLRQLCV HRVANESSRP WVWWDYVTDF 120
  121 HSRCSMKEKK YSIDCAESVI KSLNLPIEKI KKCIGDPEAD TENQVLRTEQ VSQIGRGNRG 180
  181 DVTILPTLVI NNAQYRGRLE RTAVLKAICA GFNETSEPAI CLNTGLETNE CLENNGGCWQ 240
  241 DTKANITACQ DTFRGRLCEC PVVKGVQYKG DGYTSCTPYG PARCTMNNGG CWSDTRNGLT 300
  301 FSACSDSVST GCKCPEGFQG DGLTCEDINE CKERSVCQCS GCRCKNSWGG YKCSCSGDRL 360
  361 YINDQDTCIE R

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.0
Match: 1n7dA
Description: Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.286076792172079 bayes_pls_golite062009
protein binding 0.14494900666454 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [559-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YGSKTAWWLT FLILAIVAVA GLAGYIFYKY RFRSYMDSEI MTIMSQYMPL ESQRAREVPS  60
   61 EAEPFTL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.0
Match: 1tozA
Description: NMR structure of the human NOTCH-1 ligand binding region
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle