YRC Public Data Repository - Protein Structure Prediction

Protein:	PFLB_ECOLI
Organism:	Escherichia coli
Length:	760 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PFLB_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|32033949 - gi\|32033949\|ref\|ZP_00134205.1\| COG1882: Pyruvate-formate lyase [Actinobacillus pleuropneumoniae sero... gi\|126097302, gi... - gi\|126208510\|ref\|YP_001053735.1\| formate acetyltransferase [Actinobacillus pleuropneumoniae L20], gi... gi\|190150361, gi... - gi\|190150361\|ref\|YP_001968886.1\| formate acetyltransferase [Actinobacillus pleuropneumoniae serovar ...	1187.0	[0..1]	[760..1]
gi\|194443827, gi... - gi\|194443827\|ref\|YP_002040171.1\| formate acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|194410131, gi... - gi\|194451827\|ref\|YP_002044965.1\| formate acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|194471684, gi... - gi\|194471684\|ref\|ZP_03077668.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|197213430, gi... - gi\|197249727\|ref\|YP_002145890.1\| formate acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|205339897, gi... - gi\|205339897\|gb\|EDZ26661.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar H... gi\|168263538, gi... - gi\|205347666\|gb\|EDZ34297.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar H... gi\|168466561, gi... - gi\|195630994\|gb\|EDX49580.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar N... gi\|205340731, gi... - gi\|205340731\|gb\|EDZ27495.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar W... gi\|161364157, gi... - gi\|161614793\|ref\|YP_001588758.1\| hypothetical protein SPAB_02545 [Salmonella enterica subsp. enteric... gi\|167550352, gi... - gi\|205324590\|gb\|EDZ12429.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar S... gi\|205327469, gi... - gi\|205327469\|gb\|EDZ14233.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar 4... gi\|168230868, gi... - gi\|205334836\|gb\|EDZ21600.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serovar K... gi\|206708167, gi... - gi\|207856364\|ref\|YP_002243015.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica se... gi\|213424590 - gi\|213424590\|ref\|ZP_03357373.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica ser... gi\|213648475 - gi\|213648475\|ref\|ZP_03378528.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica ser... gi\|214002575 - gi\|214002575\|ref\|ZP_03413310.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica ser... gi\|197264023, gi... - gi\|197264023\|ref\|ZP_03164097.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|197362900, gi... - gi\|197362900\|ref\|YP_002142537.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica se... gi\|197936423, gi... - gi\|198241907\|ref\|YP_002214896.1\| formate acetyltransferase [Salmonella enterica subsp. enterica sero... gi\|199603024, gi... - gi\|200390579\|ref\|ZP_03217190.1\| formate acetyltransferase [Salmonella enterica subsp. enterica serov... gi\|56413977, gi\|... - gi\|56413977\|ref\|YP_151052.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica serova... gi\|16764333, gi\|... - gi\|16764333\|ref\|NP_459948.1\| pyruvate formate lyase I [Salmonella typhimurium LT2], gi\|16419484\|gb\|A... gi\|238913254 - gi\|238913254\|ref\|ZP_04657091.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica ser... gi\|29138014, gi\|... - gi\|29142384\|ref\|NP_805726.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica serova... gi\|16502136, gi\|... - gi\|25285937\|pir\|\|AC0613 formate acetyltransferase 1 [imported] - Salmonella enterica subsp. enterica... lcl\|NC_016856.1_... - [gene=pflB] [protein=pyruvate formate lyase I] [protein_id=YP_005236689.1] [location=complement(1013... gi\|16759843 - gi\|16759843\|ref\|NP_455460.1\| formate acetyltransferase 1 [Salmonella enterica subsp. enterica serova...	1187.0	[0..1]	[760..1]
gi\|75229892, gi\|... - gi\|75229892\|ref\|ZP_00716415.1\| COG1882: Pyruvate-formate lyase [Escherichia coli B7A], gi\|191166987\|...	1186.0	[0..1]	[760..1]
gi\|187430216, gi... - gi\|75178294\|ref\|ZP_00698348.1\| COG1882: Pyruvate-formate lyase [Shigella boydii BS512], gi\|187733224... gi\|81246052, gi\|... - gi\|82544641\|ref\|YP_408588.1\| formate acetyltransferase 1 [Shigella boydii Sb227], gi\|81246052\|gb\|ABB... gi\|215264100, gi... - gi\|215486028\|ref\|YP_002328459.1\| pyruvate formate lyase I [Escherichia coli O127:H6 str. E2348/69], ...	1185.0	[0..1]	[760..1]
gi\|62127130, gi\|... - gi\|62179497\|ref\|YP_215914.1\| pyruvate formate lyase I, induced anaerobically [Salmonella enterica su...	1185.0	[0..1]	[760..1]
PFLB_ECOLI - (P09373) Formate acetyltransferase 1 (EC 2.3.1.54) (Pyruvate formate-lyase 1)	1183.0	[0..2]	[760..1]
gi\|24112311, gi\|... - gi\|24112311\|ref\|NP_706821.1\| formate acetyltransferase 1 [Shigella flexneri 2a str. 301], gi\|2405116... gi\|110804911, gi... - gi\|110804911\|ref\|YP_688431.1\| formate acetyltransferase 1 [Shigella flexneri 5 str. 8401], gi\|110614... gi\|30040684, gi\|... - gi\|30062438\|ref\|NP_836609.1\| formate acetyltransferase 1 [Shigella flexneri 2a str. 2457T], gi\|30040...	1182.0	[0..1]	[760..1]
gi\|83569142, gi\|... - gi\|83569142\|ref\|ZP_00920601.1\| COG1882: Pyruvate-formate lyase [Shigella dysenteriae 1012], gi\|19443...	1181.0	[0..1]	[760..1]
gi\|25285928, gi\|... - pir\|\|H85615 formate acetyltransferase 1 [imported] - Escherichia coli (strain O157:H7, substrain ED... gi\|254792102, gi... - gi\|254792102\|ref\|YP_003076939.1\| pyruvate formate lyase I [Escherichia coli O157:H7 str. TW14359], g... gi\|12514066, gi\|... - gi\|15800764\|ref\|NP_286778.1\| formate acetyltransferase 1 [Escherichia coli O157:H7 EDL933], gi\|12514... gi\|13360445, gi\|... - gi\|15830240\|ref\|NP_309013.1\| formate acetyltransferase 1 [Escherichia coli O157:H7], gi\|13360445\|dbj... gi\|217324930, gi... - gi\|217324930\|ref\|ZP_03441014.1\| formate acetyltransferase [Escherichia coli O157:H7 str. TW14588], g... gi\|209399377, gi... - gi\|209399377\|ref\|YP_002269575.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4115], g... gi\|218370565, gi... - gi\|218700579\|ref\|YP_002408208.1\| pyruvate formate lyase I [Escherichia coli IAI39], gi\|218370565\|emb... gi\|218694376, gi... - gi\|218694376\|ref\|YP_002402043.1\| pyruvate formate lyase I [Escherichia coli 55989], gi\|218351108\|emb... gi\|195939564 - gi\|195939564\|ref\|ZP_03084946.1\| formate acetyltransferase 1 [Escherichia coli O157:H7 str. EC4024] gi\|170681780, gi... - gi\|170681780\|ref\|YP_001744268.1\| formate acetyltransferase [Escherichia coli SMS-3-5], gi\|170519498\|... gi\|208737573, gi... - gi\|208822088\|ref\|ZP_03262407.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4042], gi... gi\|208732552, gi... - gi\|208815904\|ref\|ZP_03257083.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4045], gi... gi\|168783814, gi... - gi\|188998916\|gb\|EDU67902.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4076], gi\|168... gi\|187768347, gi... - gi\|187768347\|gb\|EDU32191.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4196], gi\|168... gi\|189376449, gi... - gi\|189376449\|gb\|EDU94865.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC508], gi\|1688... gi\|189372706, gi... - gi\|189372706\|gb\|EDU91122.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC869], gi\|1687... gi\|189355903, gi... - gi\|189355903\|gb\|EDU74322.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4401], gi\|168... gi\|168752114, gi... - gi\|188013955\|gb\|EDU52077.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4113], gi\|168... gi\|13360445, gi\|... - gi\|15830240\|ref\|NP_309013.1\| formate acetyltransferase 1 [Escherichia coli O157:H7 str. Sakai], gi\|1... gi\|189361112, gi... - gi\|189361112\|gb\|EDU79531.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4486], gi\|168... gi\|81241725, gi\|... - gi\|82777577\|ref\|YP_403926.1\| formate acetyltransferase 1 [Shigella dysenteriae Sd197], gi\|81241725\|g... gi\|168762962, gi... - gi\|189366827\|gb\|EDU85243.1\| formate acetyltransferase [Escherichia coli O157:H7 str. EC4501], gi\|168...	1181.0	[0..1]	[760..1]
gi\|75234414, gi\|... - gi\|75234414\|ref\|ZP_00718775.1\| COG1882: Pyruvate-formate lyase [Escherichia coli E110019], gi\|193070...	1181.0	[0..1]	[760..1]

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Predicted Domain #1

Region A:
Residues: [1-760]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSELNEKLAT AWEGFTKGDW QNEVNVRDFI QKNYTPYEGD ESFLAGATEA TTTLWDKVME  60
   61 GVKLENRTHA PVDFDTAVAS TITSHDAGYI NKQLEKIVGL QTEAPLKRAL IPFGGIKMIE 120
  121 GSCKAYNREL DPMIKKIFTE YRKTHNQGVF DVYTPDILRC RKSGVLTGLP DAYGRGRIIG 180
  181 DYRRVALYGI DYLMKDKLAQ FTSLQADLEN GVNLEQTIRL REEIAEQHRA LGQMKEMAAK 240
  241 YGYDISGPAT NAQEAIQWTY FGYLAAVKSQ NGAAMSFGRT STFLDVYIER DLKAGKITEQ 300
  301 EAQEMVDHLV MKLRMVRFLR TPEYDELFSG DPIWATESIG GMGLDGRTLV TKNSFRFLNT 360
  361 LYTMGPSPEP NMTILWSEKL PLNFKKFAAK VSIDTSSLQY ENDDLMRPDF NNDDYAIACC 420
  421 VSPMIVGKQM QFFGARANLA KTMLYAINGG VDEKLKMQVG PKSEPIKGDV LNYDEVMERM 480
  481 DHFMDWLAKQ YITALNIIHY MHDKYSYEAS LMALHDRDVI RTMACGIAGL SVAADSLSAI 540
  541 KYAKVKPIRD EDGLAIDFEI EGEYPQFGNN DPRVDDLAVD LVERFMKKIQ KLHTYRDAIP 600
  601 TQSVLTITSN VVYGKKTGNT PDGRRAGAPF GPGANPMHGR DQKGAVASLT SVAKLPFAYA 660
  661 KDGISYTFSI VPNALGKDDE VRKTNLAGLM DGYFHHEASI EGGQHLNVNV MNREMLLDAM 720
  721 ENPEKYPQLT IRVSGYAVRF NSLTKEQQQD VITRTFTQSM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1000.0
Match:	1h16A
Description:	Pyruvate formate-lyase, PFL
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits