YRC Public Data Repository - Protein Structure Prediction

Protein:	FABF_ECOLI
Organism:	Escherichia coli
Length:	413 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABF_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|17131773, gi\|... - gi\|17230172\|ref\|NP_486720.1\| polyketide synthase [Nostoc sp. PCC 7120], gi\|17131773\|dbj\|BAB74379.1\| ... gi\|25535295 - pir\|\|AI2140 polyketide synthase [imported] - Nostoc sp. (strain PCC 7120)	469.0	[0..4]	[410..28]
gi\|56379182, gi\|... - gi\|56419340\|ref\|YP_146658.1\| 3-oxoacyl-(acyl carrier protein) synthase II [Geobacillus kaustophilus ...	464.0	[0..1]	[412..1]
gi\|158320490, gi... - gi\|158320490\|ref\|YP_001512997.1\| Beta-ketoacyl synthase [Alkaliphilus oremlandii OhILAs], gi\|1581406...	463.0	[0..3]	[412..2]
gi\|75704032, gi\|... - gi\|75910307\|ref\|YP_324603.1\| Beta-ketoacyl synthase [Anabaena variabilis ATCC 29413], gi\|75704032\|gb...	462.0	[0..5]	[412..697]
gi\|23128252, gi\|... - gi\|23128252\|ref\|ZP_00110105.1\| COG3321: Polyketide synthase modules and related proteins [Nostoc pun...	460.0	[0..2]	[411..33]
gi\|52079631, gi\|... - gi\|52784994\|ref\|YP_090823.1\| 3-oxoacyl-(acyl carrier protein) synthase II [Bacillus licheniformis AT...	460.0	[0..1]	[412..1]
gi\|6007552 - gi\|6007552\|gb\|AAF00959.1\| McyD [Microcystis aeruginosa PCC 7806] gi\|6007552 - gi\|6007552\|gb\|AAF00959.1\|AF183408_7 McyD [Microcystis aeruginosa PCC 7806]	458.0	[0..3]	[413..2119]
gi\|78222813, gi\|... - gi\|78222813\|ref\|YP_384560.1\| 3-oxoacyl-[acyl-carrier-protein] synthase II [Geobacter metallireducens...	457.0	[0..3]	[413..1]
gi\|9955391 - gi\|9955391\|dbj\|BAB12210.1\| polyketide synthase [Microcystis aeruginosa]	457.0	[0..3]	[413..2119]

Back

Predicted Domain #1

Region A:
Residues: [1-413]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRRVVVTG LGMLSPVGNT VESTWKALLA GQSGISLIDH FDTSAYATKF AGLVKDFNCE  60
   61 DIISRKEQRK MDAFIQYGIV AGVQAMQDSG LEITEENATR IGAAIGSGIG GLGLIEENHT 120
  121 SLMNGGPRKI SPFFVPSTIV NMVAGHLTIM YGLRGPSISI ATACTSGVHN IGHAARIIAY 180
  181 GDADVMVAGG AEKASTPLGV GGFGAARALS TRNDNPQAAS RPWDKERDGF VLGDGAGMLV 240
  241 LEEYEHAKKR GAKIYAELVG FGMSSDAYHM TSPPENGAGA ALAMANALRD AGIEASQIGY 300
  301 VNAHGTSTPA GDKAEAQAVK TIFGEAASRV LVSSTKSMTG HLLGAAGAVE SIYSILALRD 360
  361 QAVPPTINLD NPDEGCDLDF VPHEARQVSG MEYTLCNSFG FGGTNGSLIF KKI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	117.0
Match:	1b3nA
Description:	Beta-ketoacyl-ACP synthase II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring acyl groups	4.09204107606289	bayes_pls_golite062009
fatty acid synthase activity	3.79121338118181	bayes_pls_golite062009
3-oxoacyl-[acyl-carrier-protein] synthase activity	3.71249191203055	bayes_pls_golite062009
C-acyltransferase activity	3.27532895419051	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	3.14957464437124	bayes_pls_golite062009
acyltransferase activity	3.06879684191353	bayes_pls_golite062009
transferase activity	2.15834234036431	bayes_pls_golite062009
catalytic activity	2.14505178497871	bayes_pls_golite062009
acetyl-CoA C-acyltransferase activity	2.06897329929762	bayes_pls_golite062009
acetyl-CoA C-acetyltransferase activity	1.50839304016514	bayes_pls_golite062009
C-acetyltransferase activity	1.19264084089277	bayes_pls_golite062009
holo-[acyl-carrier-protein] synthase activity	0.800737755066121	bayes_pls_golite062009
fatty-acyl-CoA synthase activity	0.696028474623411	bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	0.5334204157422	bayes_pls_golite062009
phosphotransferase activity, for other substituted phosphate groups	0.392307675469965	bayes_pls_golite062009
acetyltransferase activity	0.254850076259913	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: