YRC Public Data Repository - Protein Structure Prediction

Protein:	ERA_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	295 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERA_COXBU.

Description	E-value	Query Range	Subject Range
gi\|94425730, gi\|... - gi\|94502128\|ref\|ZP_01308629.1\| GTP-binding protein Era [Oceanobacter sp. RED65], gi\|94425730\|gb\|EAT1...	255.0	[0..1]	[295..1]
gi\|78700180, gi\|... - gi\|78700180\|ref\|ZP_00864637.1\| Small GTP-binding protein domain:GTP-binding:GTP-binding protein Era ...	247.0	[0..5]	[294..23]
gi\|71907658, gi\|... - gi\|71907658\|ref\|YP_285245.1\| GTP-binding protein Era [Dechloromonas aromatica RCB], gi\|71847279\|gb\|A...	247.0	[0..1]	[294..1]
ERA_COXBN - GTPase Era OS=Coxiella burnetii (strain Dugway 5J108-111) GN=era PE=3 SV=1 gi\|94491848, gi\|... - gi\|94491848\|ref\|ZP_01299058.1\| hypothetical protein CburD_01001246 [Coxiella burnetii Dugway 7E9-12]... gi\|165916972, gi... - gi\|165919312\|ref\|ZP_02219398.1\| GTP-binding protein Era [Coxiella burnetii RSA 334], gi\|165916972\|gb... gi\|120575821, gi... - gi\|153208710\|ref\|ZP_01946957.1\| GTP-binding protein Era [Coxiella burnetii 'MSU Goat Q177'], gi\|1205... ERA_COXB1 - GTPase Era OS=Coxiella burnetii (strain CbuK_Q154) GN=era PE=3 SV=1	246.0	[0..1]	[295..1]
ERA_LEUMM - GTPase Era OS=Leuconostoc mesenteroides subsp. mesenteroides (strain ATCC 8293 / NCDO 523) GN=era PE...	244.0	[0..5]	[295..7]
gi\|110647602, gi... - gi\|110834491\|ref\|YP_693350.1\| GTP-binding protein Era-like protein [Alcanivorax borkumensis SK2], gi...	243.0	[0..4]	[295..15]
gi\|22297600, gi\|... - gi\|22297600\|ref\|NP_680847.1\| GTP-binding protein Era [Thermosynechococcus elongatus BP-1], gi\|222937...	242.0	[0..5]	[294..15]
ERA_VIBVY - GTPase Era OS=Vibrio vulnificus (strain YJ016) GN=era PE=3 SV=1 ERA_VIBVU - GTPase Era OS=Vibrio vulnificus (strain CMCP6) GN=era PE=3 SV=1 ERA_VIBVU - GTPase Era OS=Vibrio vulnificus GN=era PE=3 SV=1	242.0	[0..2]	[295..22]
gi\|121628739, gi... - gi\|75815091\|ref\|ZP_00745618.1\| COG1159: GTPase [Vibrio cholerae V52], gi\|121728973\|ref\|ZP_01681977.1... gi\|227118902, gi... - gi\|75827724\|ref\|ZP_00757159.1\| COG1159: GTPase [Vibrio cholerae O395], gi\|227118902\|ref\|YP_002820798...	241.0	[0..2]	[295..26]
gi\|88779146, gi\|... - gi\|88797949\|ref\|ZP_01113536.1\| GTP-binding protein Era [Reinekea sp. MED297], gi\|88779146\|gb\|EAR1033...	241.0	[0..9]	[295..14]

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Predicted Domain #1

Region A:
Residues: [1-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPTYCGYAA IIGRPNVGKS TLLNQLLEQK ISITSRKPQT TRYQILGVKT FKDIQVIYVD  60
   61 TPGLHAGTER TINRYMNRTA RGALRDVDAI VFVIEPHWES QDAWVLDNLK EIETPVFLVI 120
  121 NKVDKIKNRA ELLPLIEKVS SLYAFQKITP LSAKTGDQVG TLEQAVHQLM PESPFYFPPE 180
  181 QVTDRSDQFM ASEIIREKLM RLLGQEIPYS LAVTLIEFRK EEKIIRISAV IWVEKKSQKG 240
  241 IVIGKGGERL KRVGTNARLD MEKWFGKRVF LQLWVKVKSG WADNERLLRE LGFEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	62.045757
Match:	1egaA
Description:	GTPase Era, N-terminal domain; GTPase Era C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	0.74089985308964	bayes_pls_golite062009
catalytic activity	0.471337605075652	bayes_pls_golite062009
binding	0.437847571554934	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: