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View Structure Prediction Details

Protein: gi|395192
Organism: Naja naja
Length: 146 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|395192.

Description E-value Query
Range
Subject
Range
PA2A2_NAJKA - Acidic phospholipase A2 2 OS=Naja kaouthia PE=1 SV=3
204.0 [0..1] [146..1]
PA2A2_NAJAT - Acidic phospholipase A2 2 OS=Naja atra PE=2 SV=1
gi|558355 - gi|558355|emb|CAA54802.1| phospholipase A2 [Naja naja]
202.0 [0..1] [146..1]
PA2AD_NAJSP - Acidic phospholipase A2 D OS=Naja sputatrix PE=1 SV=1
201.0 [0..1] [146..1]
PA2I_LATSE - Phospholipase A2 GL16-1 OS=Laticauda semifasciata PE=2 SV=1
198.0 [0..1] [146..1]
PA2A5_AUSSU - Acidic phospholipase A2 S9-53F OS=Austrelaps superbus PE=2 SV=1
194.0 [0..1] [146..1]

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Predicted Domain #1
Region A:
Residues: [1-146]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPAHLLILA AVCVSPLGAS SNRPMPLNLY QFKNMIQCTV PSRSWWDFAD YGCYCGRGGS  60
   61 GTPVDDLDRC CQVHDNCYNE AEKISGCWPY FKTYSYECSQ GTLTCKGGNN ACAAAVCDCD 120
  121 RLAAICFAGA PYNNNNYNID LKARCQ

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.221849
Match: 1gp7A
Description: Snake phospholipase A2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
phospholipase A2 activity 5.6430968678228 bayes_pls_golite062009
phospholipase activity 5.38445724291842 bayes_pls_golite062009
calcium-dependent phospholipase A2 activity 4.05813159633475 bayes_pls_golite062009
lipase activity 3.51338748073942 bayes_pls_golite062009
carboxylesterase activity 2.68079964970429 bayes_pls_golite062009
cell surface binding 2.40008700958796 bayes_pls_golite062009
receptor binding 2.23831898285432 bayes_pls_golite062009
binding 1.6033670102211 bayes_pls_golite062009
protein binding 1.47445022237761 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 1.42015803437458 bayes_pls_golite062009
hydrolase activity 1.18491761727365 bayes_pls_golite062009
heparin binding 1.06811660027805 bayes_pls_golite062009
catalytic activity 0.975181414554529 bayes_pls_golite062009
bile acid binding 0.674252334649665 bayes_pls_golite062009
glycosaminoglycan binding 0.453108206649759 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle