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View Structure Prediction Details

Protein: HIS6_NITEU
Organism: Nitrosomonas europaea ATCC 19718
Length: 258 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS6_NITEU.

Description E-value Query
Range
Subject
Range
HIS6_NITEC - Imidazole glycerol phosphate synthase subunit HisF OS=Nitrosomonas eutropha (strain C91) GN=hisF PE=...
230.0 [0..1] [258..1]

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Predicted Domain #1
Region A:
Residues: [1-258]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGLAKRIIPC LDIKDGRVVK GVNFVSLRDA GDPVEIARSY NEQGADELVF LDITASSENR  60
   61 DLILHIVEKV AAQVFIPLTV GGGVRKAEDV RRLLNAGADK VSINTSAVLN PMLIKESADH 120
  121 YGSQCIVIAI DARQIPDANP ESPRWEVFTH GGRKPTGIDA IEWAQKIQAL GAGEILLTSM 180
  181 DRDGTRSGFD LTLTRAISDS VDLPVIASGG VGHLDHLVEG ILAGHADAVL AASIFHYGEY 240
  241 SILQAKQYLS SHGIEVRL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 47.39794
Match: 1ka9F
Description: Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
imidazoleglycerol-phosphate synthase activity 8.63799159510181 bayes_pls_golite062009
catalytic activity 2.44231061702877 bayes_pls_golite062009
transferase activity, transferring pentosyl groups 1.13340776845419 bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity 0.549444136526559 bayes_pls_golite062009
tryptophan synthase activity 0.426391242491024 bayes_pls_golite062009
lyase activity 0.258652421339738 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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