YRC Public Data Repository - Protein Structure Prediction

Protein:	ACCA_ECOLI
Organism:	Escherichia coli
Length:	319 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACCA_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|71906483, gi\|... - gi\|71906483\|ref\|YP_284070.1\| acetyl-CoA carboxylase alpha subunit [Dechloromonas aromatica RCB], gi\|...	354.0	[0..1]	[318..11]
ACCA_HAEDU - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Haemophilus ducreyi GN=accA PE=3... ACCA_HAEDU - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Haemophilus ducreyi (strain 3500...	343.0	[0..1]	[318..1]
ACCA_PASMU - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Pasteurella multocida (strain Pm... ACCA_PASMU - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Pasteurella multocida GN=accA PE...	342.0	[0..1]	[318..1]
ACCA_VIBTL - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Vibrio tasmaniensis (strain LGP3... gi\|86146873, gi\|... - gi\|86146873\|ref\|ZP_01065192.1\| acetyl-CoA carboxylase alpha subunit [Vibrio sp. MED222], gi\|85835325...	342.0	[0..1]	[318..1]
gi\|56477786, gi\|... - gi\|56477786\|ref\|YP_159375.1\| acetyl-CoA carboxylase alpha subunit [Azoarcus sp. EbN1], gi\|56313829\|e...	341.0	[0..1]	[318..59]
gi\|53728816 - gi\|53728816\|ref\|ZP_00134950.2\| COG0825: Acetyl-CoA carboxylase alpha subunit [Actinobacillus pleurop... ACCA_ACTP2 - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Actinobacillus pleuropneumoniae ... ACCA_ACTPJ - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Actinobacillus pleuropneumoniae ... ACCA_ACTP7 - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Actinobacillus pleuropneumoniae ...	341.0	[0..1]	[318..1]
gi\|84376877, gi\|... - gi\|84389776\|ref\|ZP_00991328.1\| acetyl-CoA carboxylase alpha subunit [Vibrio splendidus 12B01], gi\|84...	341.0	[0..1]	[318..1]
gi\|90325477, gi\|... - gi\|90413545\|ref\|ZP_01221536.1\| acetyl-CoA carboxylase alpha subunit [Photobacterium profundum 3TCK],...	341.0	[0..1]	[318..1]
ACCA_PHOPR - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Photobacterium profundum (strain... ACCA_PHOPR - Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha OS=Photobacterium profundum GN=accA...	340.0	[0..1]	[318..1]

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Predicted Domain #1

Region A:
Residues: [1-319]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLNFLDFEQ PIAELEAKID SLTAVSRQDE KLDINIDEEV HRLREKSVEL TRKIFADLGA  60
   61 WQIAQLARHP QRPYTLDYVR LAFDEFDELA GDRAYADDKA IVGGIARLDG RPVMIIGHQK 120
  121 GRETKEKIRR NFGMPAPEGY RKALRLMQMA ERFKMPIITF IDTPGAYPGV GAEERGQSEA 180
  181 IARNLREMSR LGVPVVCTVI GEGGSGGALA IGVGDKVNML QYSTYSVISP EGCASILWKS 240
  241 ADKAPLAAEA MGIIAPRLKE LKLIDSIIPE PLGGAHRNPE AMAASLKAQL LADLADLDVL 300
  301 STEDLKNRRY QRLMSYGYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	90.522879
Match:	2f9yA
Description:	No description for 2f9yA was found.

Predicted functions:

Term	Confidence	Notes
acetyl-CoA carboxylase activity	10.6452464693016	bayes_pls_golite062009
CoA carboxylase activity	10.4560118435089	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	10.291155621143	bayes_pls_golite062009
ligase activity	5.44906329604668	bayes_pls_golite062009
biotin carboxylase activity	4.73758144982083	bayes_pls_golite062009
enoyl-CoA hydratase activity	2.20341273353803	bayes_pls_golite062009
catalytic activity	1.46154163027498	bayes_pls_golite062009
3-hydroxyacyl-CoA dehydrogenase activity	0.71437881404683	bayes_pls_golite062009
dodecenoyl-CoA delta-isomerase activity	0.712418056146834	bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing C=C bonds	0.0918189681606029	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: