YRC Public Data Repository - Protein Structure Prediction

Protein:	CHEY_ECOLI
Organism:	Escherichia coli
Length:	129 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CHEY_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|98660701 - gi\|98660701\|dbj\|GAA02123.1\| unnamed protein product [Pelotomaculum thermopropionicum SI]	162.0	[0..4]	[129..103]
gi\|110801119, gi... - gi\|110801119\|ref\|YP_695076.1\| DNA-binding response regulator [Clostridium perfringens ATCC 13124], g...	162.0	[0..1]	[129..1]
gi\|18144301, gi\|... - gi\|18309624\|ref\|NP_561558.1\| DNA-binding response regulator [Clostridium perfringens str. 13], gi\|18...	161.0	[0..1]	[129..1]
gi\|110682378, gi... - gi\|110801877\|ref\|YP_697936.1\| DNA-binding response regulator [Clostridium perfringens SM101], gi\|110...	159.0	[0..1]	[127..1]
gi\|85859021, gi\|... - gi\|85859021\|ref\|YP_461223.1\| response regulator [Syntrophus aciditrophicus SB], gi\|85722112\|gb\|ABC77...	159.0	[0..1]	[127..10]
gi\|28210824, gi\|... - gi\|28210824\|ref\|NP_781768.1\| transcriptional regulatory protein [Clostridium tetani E88], gi\|2820326...	156.0	[0..1]	[126..1]
gi\|42780487, gi\|... - gi\|42780487\|ref\|NP_977734.1\| DNA-binding response regulator [Bacillus cereus ATCC 10987], gi\|4273640... gi\|222095033, gi... - gi\|222095033\|ref\|YP_002529093.1\| response regulator [Bacillus cereus Q1], gi\|221239091\|gb\|ACM11801.1... gi\|217068126, gi... - gi\|217958874\|ref\|YP_002337422.1\| DNA-binding response regulator [Bacillus cereus AH187], gi\|21706812... gi\|206977570, gi... - gi\|206977570\|ref\|ZP_03238464.1\| DNA-binding response regulator [Bacillus cereus H3081.97], gi\|206744...	156.0	[0..4]	[127..2]
gi\|48860348, gi\|... - gi\|67873291\|ref\|ZP_00503570.1\| Response regulator receiver:Transcriptional regulatory protein, C ter...	156.0	[0..1]	[127..1]
gi\|47556738, gi\|... - gi\|47566185\|ref\|ZP_00237213.1\| two-component response regulator [Bacillus cereus G9241], gi\|47556738...	155.0	[0..5]	[127..3]
gi\|77996843, gi\|... - gi\|78044728\|ref\|YP_360866.1\| DNA-binding response regulator [Carboxydothermus hydrogenoformans Z-290...	154.0	[0..6]	[126..1]

Back

Predicted Domain #1

Region A:
Residues: [1-129]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADKELKFLV VDDFSTMRRI VRNLLKELGF NNVEEAEDGV DALNKLQAGG YGFVISDWNM  60
   61 PNMDGLELLK TIRADGAMSA LPVLMVTAEA KKENIIAAAQ AGASGYVVKP FTAATLEEKL 120
  121 NKIFEKLGM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.045757
Match:	1djmA
Description:	CheY protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
two-component response regulator activity	7.02872640261738	bayes_pls_golite062009
signal transducer activity	4.51666042720644	bayes_pls_golite062009
molecular transducer activity	4.51666042720644	bayes_pls_golite062009
transcription regulator activity	3.44888100104099	bayes_pls_golite062009
protein histidine kinase activity	2.35011582062573	bayes_pls_golite062009
two-component sensor activity	2.32303301074957	bayes_pls_golite062009
phosphotransferase activity, nitrogenous group as acceptor	2.28838869071567	bayes_pls_golite062009
binding	1.22427537074115	bayes_pls_golite062009
DNA binding	1.11037597107903	bayes_pls_golite062009
nucleic acid binding	1.05519146337499	bayes_pls_golite062009
protein kinase activity	0.73223373303195	bayes_pls_golite062009
transcription factor activity	0.62886970109503	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	0.483665536682372	bayes_pls_golite062009
kinase activity	0.354820297776097	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.126415734125785	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: