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View Structure Prediction Details

Protein: ATG4A_ARATH
Organism: Arabidopsis thaliana
Length: 467 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG4A_ARATH.

Description E-value Query
Range
Subject
Range
gi|3212867, gi|7... - pir||T00694 hypothetical protein At2g44140 [imported] - Arabidopsis thaliana, gi|3212867|gb|AAC23418...
591.0 [0..1] [467..1]
gi|74008589 - gi|74008589|ref|XP_538136.2| PREDICTED: similar to autophagy-related cysteine endopeptidase 2 isofor...
500.0 [0..36] [467..4]
ATG4A_ORYSJ - Cysteine protease ATG4A OS=Oryza sativa subsp. japonica GN=ATG4A PE=2 SV=1
492.0 [0..9] [467..4]
gi|125550266, gi... - gi|90399070|emb|CAJ86292.1| H0124B04.9 [Oryza sativa (indica cultivar-group)], gi|125550266|gb|EAY96...
486.0 [0..9] [458..275]
gi|113413579 - gi|113413579|ref|XP_001126139.1| PREDICTED: similar to APG4 autophagy 4 homolog B isoform a [Homo sa...
473.0 [0..99] [467..102]

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Predicted Domain #1
Region A:
Residues: [1-105]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKALCDRFVP QQCSSSSKSD THDKSPLVSD SGPSDNKSKF TLWSNVFTSS SSVSQPYRES  60
   61 STSGHKQVCT TRNGWTAFVK RVSMASGAIR RFQERVLGPN RTGLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.595 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.595 a.24.7 FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View Download 0.385 a.24.18 Description not found.
View Download 0.271 a.40.1 Calponin-homology domain, CH-domain
View Download 0.271 a.40.1 Calponin-homology domain, CH-domain
View Download 0.269 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17
View Download 0.262 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.262 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.235 a.165.1 Myosin phosphatase inhibitor 17kDa protein, CPI-17

Predicted Domain #2
Region A:
Residues: [106-467]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STTSDVWLLG VCYKISADEN SGETDTGTVL AALQLDFSSK ILMTYRKGFE PFRDTTYTSD  60
   61 VNWGCMIRSS QMLFAQALLF HRLGRAWTKK SELPEQEYLE TLEPFGDSEP SAFSIHNLII 120
  121 AGASYGLAAG SWVGPYAICR AWESLACKKR KQTDSKNQTL PMAVHIVSGS EDGERGGAPI 180
  181 LCIEDATKSC LEFSKGQSEW TPIILLVPLV LGLDSVNPRY IPSLVATFTF PQSVGILGGK 240
  241 PGASTYIVGV QEDKGFYLDP HEVQQVVTVN KETPDVDTSS YHCNVLRYVP LESLDPSLAL 300
  301 GFYCRDKDDF DDFCLRALKL AEESNGAPLF TVTQTHTAIN QSNYGFADDD SEDEREDDWQ 360
  361 ML

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 133.0
Match: 2d1iA
Description: Structure of human Atg4b
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle