YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|14150691
Organism:	Plasmodium falciparum
Length:	1189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|14150691.

Description	E-value	Query Range	Subject Range
gi\|116000599 - gi\|116000599\|emb\|CAL50279.1\| putative transitional endoplasmic reticulum ATPase (ISS) [Ostreococcus ...	472.0	[0..624]	[1189..65]
gi\|66934627 - gi\|66934627\|gb\|AAY58902.1\| putative CDC48/ATPase [Hyaloperonospora parasitica]	470.0	[0..613]	[1189..4]
gi\|145010540, gi... - gi\|39940094\|ref\|XP_359584.1\| cell division control protein Cdc48 [Magnaporthe grisea 70-15], gb\|EAA5...	464.0	[0..603]	[1189..16]
CDC48_SOYBN - Cell division cycle protein 48 homolog OS=Glycine max GN=CDC48 PE=2 SV=1	463.0	[0..606]	[1183..6]
gi\|116207434, gi... - gi\|88183607\|gb\|EAQ91075.1\| hypothetical protein CHGG_03010 [Chaetomium globosum CBS 148.51], gi\|1162...	463.0	[0..603]	[1189..18]
gi\|111061548, gi... - gi\|169614385\|ref\|XP_001800609.1\| hypothetical protein SNOG_10333 [Phaeosphaeria nodorum SN15], gi\|11...	462.0	[0..591]	[1189..13]
gi\|83423461, gi\|... - gi\|95102992\|gb\|ABF51437.1\| transitional endoplasmic reticulum ATPase TER94 [Bombyx mori], gi\|8342346...	462.0	[0..609]	[1189..2]
gi\|66534286 - gi\|66534286\|ref\|XP_392892.2\| PREDICTED: similar to TER94 CG2331-PA, isoform A isoform 1 [Apis mellif...	461.0	[0..604]	[1189..7]
gi\|114187782, gi... - gi\|115385577\|ref\|XP_001209335.1\| cell division cycle protein 48 [Aspergillus terreus NIH2624], gi\|11...	461.0	[0..603]	[1189..16]
gi\|119174931, gi... - gi\|90298572\|gb\|EAS28203.1\| hypothetical protein CIMG_09407 [Coccidioides immitis RS], gi\|119174931\|r... gi\|240106991 - gi\|240106991\|gb\|EER25178.1\| Cell division control protein 48, putative [Coccidioides posadasii C735 ...	460.0	[0..609]	[1189..22]

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Predicted Domain #1

Region A:
Residues: [1-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTPKKKIFQN FQANDNEILS PTKKGIKLNV SKLNILNFEN TIITKEKTNY EYKASLNKEI  60
   61 DEVLNNNNII NTHNNKKNNL NLYDYNNIKN STHEFYIDLN EQNKQTIKYN DNKFTPINKK 120
  121 EKYNLDETSS SSISSSLTNI SSSLTNISSS LTNISSSLSN SLDEKKKKKK IKKNNSTIIN 180
  181 ILNNNNNNSN IHHNNKHNIY NKYNISKKPQ NKEIHTLPSN HQIKKKSNNT YNTCQQKMKK 240
  241 NISKKNTHSI KNNQNDKNKE KNKEKDKNIK KDRDKDIQTK RTSHQSQDQN NHFERRILRS 300
  301 YTRNNDNVKN NLKNNINNNN TLKRSSQSVR IDSDLSSAHQ NKRIKYDEKN IIHRNNNNNN 360
  361 NNNNKTTSNN HNKNNKINNN NPSENYKKQT DTKHTNNTQN NKYNKTKTTN TFKHPSKDHT 420
  421 DVNTKTFKSR YINTYTMEEV QKSIKSNTIK LVQENSCEYQ DGIIYESIQI NDEEYSIGED 480
  481 VLIFYTPNN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.522879
Match:	1epwA
Description:	Botulinum neurotoxin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [490-604]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NTYNAKSDDK KNQNNNNIKE NIYLLKKGKI SSFYKSTNSK VIEVEICFYY DESDEQRIRE  60
   61 LEKKQTSRRC KEDFNIYLDD DTKYYNLLGN IHFTILDANY IYKKIYVYNE IETFE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.447	0.808	nucleoside-triphosphatase activity	b.1.1	Immunoglobulin

Predicted Domain #3

Region A:
Residues: [605-1189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EDTHARKGKN KFLCTHFIKD KEDRLCFIPN EDHWDNLVLG SSDLYYYFAN EKKLNKNKSL  60
   61 KLIIEKLKIN DKINDTQANQ KKNNKKEYMN KAQTTTNVKA NTHTKTLNDH NKSKTTKNKE 120
  121 SSSTSFLQDV KKKSDPHNND FQSSLKEDQE NYYINLLKNI KDPTDKAIRM MQLDVVPKYL 180
  181 PCREKEIKEV HGFLESGIKQ SGSNQILYIS GMPGTGKTAT VYSVIQLLQI KSRKKLLPSF 240
  241 NVFEINGMNV VHPNAAYQVF YKQLFNKKPP NALNSFKIID RLFNKSQKDN RDVSILIIDE 300
  301 IDYLITKTQK VLFTLFDWPT KINSKLILIA ISNTMDLPDR LIPRCRSRLA FGRLVFSPYK 360
  361 GDEIEKIIKE RLENCKEIID HTAIQLCARK VANVSGDIRK ALQICRKAFE NKRGHKIVPR 420
  421 DITEATNQLF DSPLTNAINY LPWAFKIFLT CLIIELRIIN EFVIPYKKVV NRYKILIETS 480
  481 GKYIGMCSDN ELFKIMLDKL VKMGILLIRP YIPLENISKN KSKEALLGFN ESSKKGNNQK 540
  541 ITRAQVSPDI DKESGDMGIE LNVETQLIIT ALMKDPDCSK KLNFY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	126.0
Match:	1r7rA
Description:	The crystal structure of murine p97/VCP at 3.6A
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.237569247811196	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: