YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25339783
Organism:	Yersinia pestis
Length:	189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25339783.

Description	E-value	Query Range	Subject Range
gi\|169772989 - gi\|169772989\|ref\|XP_001820963.1\| hypothetical protein [Aspergillus oryzae RIB40] gi\|83768824 - gi\|83768824\|dbj\|BAE58961.1\| unnamed protein product [Aspergillus oryzae]	9.0E-39	[8..189]	[3..184]
gi\|45442459, gi\|... - gi\|45442459\|ref\|NP_993998.1\| Glycine cleavage system regulatory protein [Yersinia pestis biovar Micr...	1.0E-38	[1..189]	[50..238]
gi\|89104851, gi\|... - gi\|89104851\|ref\|ZP_01177383.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia pestis ... gi\|108780161, gi... - gi\|108808248\|ref\|YP_652164.1\| glycine cleavage system transcriptional repressor [Yersinia pestis Ant... gi\|51597100, gi\|... - gi\|51597100\|ref\|YP_071291.1\| glycine cleavage system transcriptional repressor [Yersinia pseudotuber... Q668F6\|Q668F6_YERPS - Glycine cleavage system transcriptional repressor - Yersinia pseudotuberculosis gi\|108811485, gi... - gi\|108811485\|ref\|YP_647252.1\| glycine cleavage system transcriptional repressor [Yersinia pestis Nep... gi\|186699218, gi... - gi\|186896192\|ref\|YP_001873304.1\| glycine cleavage system transcriptional repressor [Yersinia pseudot... gi\|167424519, gi... - gi\|167424519\|ref\|ZP_02316272.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|170023603, gi... - gi\|170023603\|ref\|YP_001720108.1\| glycine cleavage system transcriptional repressor [Yersinia pseudot... gi\|162351186, gi... - gi\|77636334\|ref\|ZP_00798409.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia pestis ... gi\|117672946, gi... - gi\|77629828\|ref\|ZP_00792414.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia pseudot... gi\|145211138, gi... - gi\|145599442\|ref\|YP_001163518.1\| glycine cleavage system transcriptional repressor [Yersinia pestis ... gi\|166212485, gi... - gi\|166212485\|ref\|ZP_02238520.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|167422708, gi... - gi\|167422708\|ref\|ZP_02314461.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|165989903, gi... - gi\|166011225\|ref\|ZP_02232123.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b...	2.0E-38	[1..189]	[16..204]
gi\|83723946, gi\|... - gi\|83749369\|ref\|ZP_00946364.1\| Formyltetrahydrofolate deformylase [Ralstonia solanacearum UW551], gi...	2.0E-38	[8..188]	[32..213]
gi\|238783852, gi... - gi\|77958977\|ref\|ZP_00823002.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia bercovi...	3.0E-38	[1..189]	[16..204]
gi\|54208728 - gi\|54208728\|gb\|AAV31123.1\| glycine cleavage system transcriptional repressor [Yersinia ruckeri]	5.0E-38	[1..189]	[16..204]
gi\|77977633 - gi\|77977633\|ref\|ZP_00833076.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia interme...	5.0E-38	[1..189]	[16..204]
gi\|94311174, gi\|... - gi\|94311174\|ref\|YP_584384.1\| formyltetrahydrofolate deformylase [Ralstonia metallidurans CH34], gi\|9...	5.0E-38	[8..188]	[5..186]
gi\|32141235, gi\|... - gi\|32141235\|ref\|NP_733636.1\| formyltetrahydrofolate deformylase [Streptomyces coelicolor A3(2)], gi\|...	6.0E-38	[3..189]	[13..196]
gi\|187479291, gi... - gi\|187479291\|ref\|YP_787316.1\| formyltetrahydrofolate deformylase [Bordetella avium 197N], gi\|1154238...	7.0E-38	[7..189]	[4..183]

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Predicted Domain #1

Region A:
Residues: [1-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPQLDEHYLV ITALGADRPG IVNTITRHVS SCGCNIEDSR LAMFGEEFTF IMLLSGSWNA  60
   61 VTLLESTLPQ KGAELDLLIV MKRTNAQGQK AMPTTVWVKV EVNDSPHIIE RFTNLFHCHN 120
  121 MNIAELVSKT QPADGETPPL LHIQMSAHSP ASQNSSIIEH DFYQLCTELN AQGSISVVSY 180
  181 PQHDDRMES

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.045757
Match:	1u8sA
Description:	Crystal structure of putative glycine cleavage system transcriptional repressor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	1.8426895540113	bayes_pls_golite062009
transcription regulator activity	1.42429440534204	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.932189330120355	bayes_pls_golite062009
binding	0.824916443468813	bayes_pls_golite062009
nucleic acid binding	0.802049795170512	bayes_pls_golite062009
catalytic activity	0.645256181736122	bayes_pls_golite062009
DNA binding	0.580950464710662	bayes_pls_golite062009
protein binding	0.0634623326053931	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: