YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|15978185, gi\|...
Organism:	Yersinia pestis CO92
Length:	354 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|15978185, gi|....

Description	E-value	Query Range	Subject Range
gi\|152961471, gi... - gi\|77630852\|ref\|ZP_00793438.1\| COG2169: Adenosine deaminase [Yersinia pseudotuberculosis IP 31758], ...	3.0E-68	[1..354]	[1..354]
gi\|77960030, gi\|... - gi\|77960030\|ref\|ZP_00823930.1\| COG2169: Adenosine deaminase [Yersinia mollaretii ATCC 43969], gi\|238...	5.0E-68	[6..352]	[26..372]
gi\|186467753, gi... - gi\|23130248\|ref\|ZP_00112065.1\| COG2169: Adenosine deaminase [Nostoc punctiforme PCC 73102], gi\|18668...	2.0E-67	[3..345]	[8..351]
Q66GB4\|Q66GB4_YERPS - Bifunctional regulatory protein/DNA repair protein - Yersinia pseudotuberculosis gi\|51587708, gi\|... - gi\|51594426\|ref\|YP_068617.1\| bifunctional regulatory protein/DNA repair protein [Yersinia pseudotube...	5.0E-67	[1..354]	[1..354]
gi\|238726289, gi... - gi\|77977376\|ref\|ZP_00832826.1\| COG2169: Adenosine deaminase [Yersinia intermedia ATCC 29909], gi\|238...	2.0E-66	[6..346]	[19..359]
gi\|77459163, gi\|... - gi\|77459163\|ref\|YP_348669.1\| AraC family transcriptional regulator [Pseudomonas fluorescens Pf0-1], ...	6.0E-66	[5..346]	[12..353]
gi\|238783968, gi... - gi\|77958481\|ref\|ZP_00822514.1\| COG2169: Adenosine deaminase [Yersinia bercovieri ATCC 43970], gi\|238...	2.0E-65	[6..353]	[26..373]
gi\|227887271, gi... - gi\|227887271\|ref\|ZP_04005076.1\| O6-methylguanine-DNA methyltransferase; transcription activator/repr... gi\|26248600, gi\|... - gi\|26248600\|ref\|NP_754640.1\| ADA regulatory protein [Escherichia coli CFT073], gi\|26109005\|gb\|AAN812...	3.0E-65	[3..345]	[7..348]
gi\|75243029, gi\|... - gi\|75243029\|ref\|ZP_00726735.1\| COG2169: Adenosine deaminase [Escherichia coli F11], gi\|191169958\|ref... gi\|110344015, gi... - gi\|110642423\|ref\|YP_670153.1\| ADA regulatory protein [Escherichia coli 536], gi\|110344015\|gb\|ABG7025...	6.0E-65	[3..351]	[7..354]
gi\|24052652, gi\|... - gi\|24113598\|ref\|NP_708108.1\| O6-methylguanine-DNA methyltransferase; transcription activator/repress... gi\|81245964, gi\|... - gi\|82544553\|ref\|YP_408500.1\| O6-methylguanine-DNA methyltransferase; transcription activator/repress... gi\|73856211, gi\|... - gi\|74312734\|ref\|YP_311153.1\| O6-methylguanine-DNA methyltransferase [Shigella sonnei Ss046], gi\|7385... gi\|110806187, gi... - gi\|110806187\|ref\|YP_689707.1\| O6-methylguanine-DNA methyltransferase; transcription activator/repres... gi\|30063652, gi\|... - gi\|30063652\|ref\|NP_837823.1\| O6-methylguanine-DNA methyltransferase; transcription activator/repress...	8.0E-65	[3..351]	[7..354]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNVKDPRWA AIINRDKTAD GQFVYAVKTT GIYCRPSCPS RRAKAENIEF FIDNTAAEQA  60
   61 GYRPCKRCQP TQLSRAQQQV EKISQACRLI ELAETPPKLN ELAAQLGLST FYFHRLFKAI 120
  121 TGLTPKGYAN ATRSERIRAQ LSHGGSVTDA IFEAGYNSSS RFYAQSQQLL GMTPTRYRKG 180
  181 GCDARLHFAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	20.522879
Match:	1wpkA
Description:	Methylated Form of N-terminal Transcriptional Regulator Domain of Escherichia Coli Ada Protein
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [191-354]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GESSLGAILV AKSELGVCAI LLGDDPVRLV QQLQDKFPQA NLVGGDAEFE QWVAQVVGCV  60
   61 EAPKLGLNLP LDIRGTAFQQ RVWQALREIP IGETASYADI ASRIGSPTAV RAVAGACAAN 120
  121 ILAVAIPCHR VIRQDGALSG YRWGVERKRL LLEREGVEKE AEDH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.30103
Match:	1sfeA
Description:	ADA O6-METHYLGUANINE-DNA METHYLTRANSFERASE FROM ESCHERICHIA COLI
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methylated-DNA-[protein]-cysteine S-methyltransferase activity	3.9938943760254	bayes_pls_golite062009
S-methyltransferase activity	2.96219931728042	bayes_pls_golite062009
catalytic activity	2.27882522649583	bayes_pls_golite062009
methyltransferase activity	1.63681159093596	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.6341981985862	bayes_pls_golite062009
transcription regulator activity	1.50560845180409	bayes_pls_golite062009
transferase activity	1.42883081715544	bayes_pls_golite062009
nucleic acid binding	1.31078533764756	bayes_pls_golite062009
DNA binding	1.30370233516088	bayes_pls_golite062009
transcription factor activity	0.92641016171542	bayes_pls_golite062009
binding	0.56079831494733	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: