YRC Public Data Repository - Protein Structure Prediction

Protein:	GLMU_SALTI
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	456 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GLMU_SALTI.

Description	E-value	Query Range	Subject Range
GLMU_SALTY - Bifunctional protein GlmU OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=glmU PE... GLMU_SALTY - Bifunctional protein glmU OS=Salmonella typhimurium GN=glmU PE=3 SV=1 gi\|195632226, gi... - gi\|195632226\|gb\|EDX50710.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_SALHS - Bifunctional protein GlmU OS=Salmonella heidelberg (strain SL476) GN=glmU PE=3 SV=1 gi\|167995196, gi... - gi\|205327084\|gb\|EDZ13848.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... gi\|205336006, gi... - gi\|205336006\|gb\|EDZ22770.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_SALTY - Bifunctional protein GlmU OS=Salmonella typhimurium GN=glmU PE=3 SV=1 lcl\|NC_016856.1_... - [gene=glmU] [protein=bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-ph...	6.0E-86	[1..456]	[1..456]
GLMU_SALCH - Bifunctional protein glmU OS=Salmonella choleraesuis GN=glmU PE=3 SV=1 GLMU_SALCH - Bifunctional protein GlmU OS=Salmonella choleraesuis (strain SC-B67) GN=glmU PE=3 SV=1 GLMU_SALCH - Bifunctional protein GlmU OS=Salmonella choleraesuis GN=glmU PE=3 SV=1	2.0E-85	[1..456]	[1..456]
GLMU_SALPA - Bifunctional protein GlmU OS=Salmonella paratyphi A GN=glmU PE=3 SV=1 GLMU_SALPK - Bifunctional protein GlmU OS=Salmonella paratyphi A (strain AKU_12601) GN=glmU PE=3 SV=1 GLMU_SALPA - Bifunctional protein GlmU OS=Salmonella paratyphi A (strain ATCC 9150 / SARB42) GN=glmU PE=3 SV=1	2.0E-85	[1..456]	[1..456]
GLMU_ECOUT - Bifunctional protein GlmU OS=Escherichia coli (strain UTI89 / UPEC) GN=glmU PE=3 SV=1 GLMU_ECOK1 - Bifunctional protein GlmU OS=Escherichia coli O1:K1 / APEC GN=glmU PE=3 SV=1 GLMU_ECO45 - Bifunctional protein GlmU OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=glmU PE=3 SV=1 gi\|237703531, gi... - gi\|237703531\|ref\|ZP_04534012.1\| glmU [Escherichia sp. 3_2_53FAA], gi\|226902795\|gb\|EEH89054.1\| glmU [...	1.0E-84	[1..456]	[1..456]
GLMU_ECOLC - Bifunctional protein GlmU OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=glmU PE=3 SV... GLMU_ECOLU - Bifunctional protein GlmU OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=glmU PE=3 SV=1 gi\|194431307, gi... - gi\|194431307\|ref\|ZP_03063600.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... GLMU_ECOHS - Bifunctional protein GlmU OS=Escherichia coli O9:H4 (strain HS) GN=glmU PE=3 SV=1 gi\|194425154, gi... - gi\|194435611\|ref\|ZP_03067714.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... GLMU_ECO24 - Bifunctional protein GlmU OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=glmU PE=3 SV=1 GLMU_ECOSE - Bifunctional protein GlmU OS=Escherichia coli (strain SE11) GN=glmU PE=3 SV=1 gi\|217325782, gi... - gi\|217325782\|ref\|ZP_03441866.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... GLMU_ECOSM - Bifunctional protein GlmU OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=glmU PE=3 SV=1 gi\|190904126, gi... - gi\|191165802\|ref\|ZP_03027640.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... gi\|192930481, gi... - gi\|193063766\|ref\|ZP_03044853.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... gi\|194428118, gi... - gi\|194428118\|ref\|ZP_03060662.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... GLMU_ECOBW - Bifunctional protein GlmU OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=glmU PE=3 SV=1 gi\|242379268, gi... - gi\|251786995\|ref\|YP_003001299.1\| hypothetical protein B21_03558 [Escherichia coli BL21], gi\|24237926... gi\|124530056, gi... - gi\|124530056\|ref\|ZP_01700839.1\| UDP-N-acetylglucosamine pyrophosphorylase [Escherichia coli B], gi\|1... gi\|254163682, gi... - gi\|254163682\|ref\|YP_003046790.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluc... gi\|253979739, gi... - gi\|254290432\|ref\|YP_003056180.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluc... gi\|226838914, gi... - gi\|254038949\|ref\|ZP_04873001.1\| glmU [Escherichia sp. 1_1_43], gi\|226838914\|gb\|EEH70941.1\| glmU [Esc... gi\|15833926, gi\|... - gi\|15833926\|ref\|NP_312699.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... GLMU_ECO57 - Bifunctional protein GlmU OS=Escherichia coli O157:H7 GN=glmU PE=3 SV=1 GLMU_ECOLI - Bifunctional protein glmU [Includes: UDP-N-acetylglucosamine pyrophosphorylase (EC 2.7.7.23) (N-acet... EG11198 - fused N-acetyl glucosamine-1-phosphate uridyltransferase /glucosamine-1-phosphate acetyl transferase ... gi\|85676308, gi\|... - gi\|89110277\|ref\|AP_004057.1\| fused N-acetyl glucosamine-1-phosphate uridyltransferase and glucosamin... EG11198 - fused N-acetyl glucosamine-1-phosphate uridyltransferase /glucosamine-1-phosphate acetyl transferase ... gi\|189369811, gi... - gi\|189369811\|gb\|EDU88227.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... gi\|168786573, gi... - gi\|189373436\|gb\|EDU91852.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyl... GLMU_ECODH - Bifunctional protein GlmU OS=Escherichia coli (strain K12 / DH10B) GN=glmU PE=3 SV=1	1.0E-84	[1..456]	[1..456]
gi\|24115033, gi\|... - gi\|24115033\|ref\|NP_709543.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... gi\|30043226, gi\|... - gi\|30064965\|ref\|NP_839136.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosam... GLMU_SHIFL - Bifunctional protein GlmU OS=Shigella flexneri GN=glmU PE=3 SV=1 GLMU_SHIF8 - Bifunctional protein GlmU OS=Shigella flexneri serotype 5b (strain 8401) GN=glmU PE=3 SV=1	1.0E-84	[1..456]	[1..456]
GLMU_ECOL6 - Bifunctional protein GlmU OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=glmU PE=... GLMU_ECOL6 - Bifunctional protein GlmU OS=Escherichia coli O6 GN=glmU PE=3 SV=1 gi\|227883952, gi... - gi\|227883952\|ref\|ZP_04001757.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluco...	1.0E-84	[1..456]	[1..456]
gi\|190909357, gi... - gi\|191170549\|ref\|ZP_03032102.1\| UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-ac... GLMU_ECOL5 - Bifunctional protein GlmU OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=glmU PE=3 SV=1	1.0E-84	[1..456]	[1..456]
GLMU_SHIDS - Bifunctional protein GlmU OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=glmU PE=3 SV=1	1.0E-84	[1..456]	[1..456]
gi\|229839827, gi... - gi\|229839827\|ref\|ZP_04459986.1\| bifunctional N-acetyl glucosamine-1-phosphate uridyltransferase/gluc... gi\|229691251, gi... - gi\|229841912\|ref\|ZP_04462068.1\| bifunctional N-acetyl glucosamine-1-phosphate uridyltransferase/gluc... GLMU_YERPS - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis GN=glmU PE=3 SV=1 gi\|229896789, gi... - gi\|229896789\|ref\|ZP_04511952.1\| bifunctional N-acetyl glucosamine-1-phosphate uridyltransferase/gluc... GLMU_YERPA - Bifunctional protein GlmU OS=Yersinia pestis bv. Antiqua (strain Antiqua) GN=glmU PE=3 SV=1 GLMU_YERPB - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype IB (strain PB1/+) GN=glmU PE=3 SV=... GLMU_YERPN - Bifunctional protein GlmU OS=Yersinia pestis bv. Antiqua (strain Nepal516) GN=glmU PE=3 SV=1 gi\|167468117 - gi\|167468117\|ref\|ZP_02332821.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis FV-1] GLMU_YERPY - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype O:3 (strain YPIII) GN=glmU PE=3 SV... GLMU_YERPE - Bifunctional protein GlmU OS=Yersinia pestis GN=glmU PE=1 SV=1 gi\|218931095, gi... - gi\|218931095\|ref\|YP_002348970.1\| bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/gluc... GLMU_YERPS - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=glmU PE=3 SV... GLMU_YERP3 - Bifunctional protein GlmU OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=glmU PE=... gi\|149290355, gi... - gi\|150260947\|ref\|ZP_01917675.1\| UDP-N-acetylglucosamine pyrophosphorylase [Yersinia pestis CA88-4125... GLMU_YERPP - Bifunctional protein GlmU OS=Yersinia pestis (strain Pestoides F) GN=glmU PE=1 SV=1	1.0E-84	[1..456]	[1..456]

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Predicted Domain #1

Region A:
Residues: [1-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLNSAMSVVI LAAGKGTRMY SDIPKVLHTL AGKPMVQHVI DAATKLGAAQ VHLVYGHGGE  60
   61 LLKQTLKDDK LNWVLQAEQL GTGHAMQQAA PFFSDDEDIL MLYGDVPLIS VETLQRLRDA 120
  121 KPQGGIGLLT VKLDDPSGYG RITRENGKVT GIVEHKDATD EQRQIQEINT GILIANGADL 180
  181 KRWLSKLTNN NAQGEYYITD IIALAYQEGR EIAAVHPARI SETDGVNNRL QLSRLERIYQ 240
  241 AEQAEKLLLS GVMLRDPARF DLRGTLYCGM DVEIDANVII EGYVTLGHRV KIGAGCIIKN 300
  301 SVIGDDCEIS PYSVVEDAHL EAACTIGPFA RLRPGAELLA GAHVGNFVEM KKARLGKGSK 360
  361 AGHLTYLGDA EIGDNVNIGA GTITCNYDGA NKFKTVIGDD VFVGSDTQLV APVTVGKGAT 420
  421 IAAGTTVTRN VADNELVLSR VPQVHKQGWQ RPVKKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	86.221849
Match:	1hv9A
Description:	N-acetylglucosamine 1-phosphate uridyltransferase GlmU, C-terminal domain; N-acetylglucosamine 1-phosphate uridyltransferase GlmU, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity	4.85526297527966	bayes_pls_golite062009
O-acyltransferase activity	4.84577168407664	bayes_pls_golite062009
uridylyltransferase activity	2.78377598963895	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.55498472336996	bayes_pls_golite062009
UDP-glycosyltransferase activity	2.14294822366154	bayes_pls_golite062009
UTP:glucose-1-phosphate uridylyltransferase activity	2.04683358427931	bayes_pls_golite062009
UTP-monosaccharide-1-phosphate uridylyltransferase activity	1.90086040617591	bayes_pls_golite062009
catalytic activity	1.88676710996045	bayes_pls_golite062009
transferase activity	1.47184463413038	bayes_pls_golite062009
nucleotidyltransferase activity	1.17054423506287	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	1.09519444695756	bayes_pls_golite062009
cytidylyltransferase activity	0.983416157001861	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	0.897978517422275	bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity	0.857216989692536	bayes_pls_golite062009
mannosyltransferase activity	0.64885729959093	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.521566400238457	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.513376694534047	bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity	0.2363835251362	bayes_pls_golite062009
guanylyltransferase activity	0.0539392112504681	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: