YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16503707, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16503707, gi|....

Description	E-value	Query Range	Subject Range
gi\|16421032, gi\|... - gi\|16765810\|ref\|NP_461425.1\| gcv operon transcriptional repressor [Salmonella typhimurium LT2], gi\|1...	3.0E-53	[1..212]	[1..212]
gi\|56126885, gi\|... - gi\|56412628\|ref\|YP_149703.1\| glycine cleavage system transcriptional repressor [Salmonella enterica ...	4.0E-53	[1..212]	[1..212]
gi\|13362811 - gi\|13362811\|dbj\|BAB36764.1\| transcriptional regulation of gcv operon [Escherichia coli O157:H7 str. ... gi\|13362811 - gi\|13362811\|dbj\|BAB36764.1\| transcriptional regulation of gcv operon [Escherichia coli O157:H7] gi\|209763694, gi... - pir\|\|F65023 gcvR protein - Escherichia coli (strain K-12), pir\|\|A85891 transcription regulation of ... gi\|12516861, gi\|... - gi\|15803002\|ref\|NP_289032.1\| transcriptional regulation of gcv operon [Escherichia coli O157:H7 EDL9... gi\|49176227, gi\|... - gi\|49176227\|ref\|NP_416974.3\| transcriptional regulation of gcv operon [Escherichia coli K12], gb\|AAC... gi\|209913213, gi... - gi\|209919954\|ref\|YP_002294038.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|188488765, gi... - gi\|188493566\|ref\|ZP_03000836.1\| ACT domain protein [Escherichia coli 53638], gi\|188488765\|gb\|EDU6386... gi\|187733494, gi... - gi\|187733494\|ref\|YP_001881271.1\| glycine cleavage system transcriptional repressor [Shigella boydii ... gi\|82777861, gi\|... - gi\|82777861\|ref\|YP_404210.1\| transcriptional regulation of gcv operon [Shigella dysenteriae Sd197], ... gi\|81246338, gi\|... - gi\|82544927\|ref\|YP_408874.1\| GcvR [Shigella boydii Sb227], gi\|81246338\|gb\|ABB67046.1\| GcvR [Shigella... gi\|73856482, gi\|... - gi\|74313005\|ref\|YP_311424.1\| transcriptional regulation of gcv operon [Shigella sonnei Ss046], gi\|73... gi\|157161941, gi... - gi\|157161941\|ref\|YP_001459259.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|157158641, gi... - gi\|157158641\|ref\|YP_001463804.1\| glycine cleavage system transcriptional repressor [Escherichia coli...	3.0E-52	[1..212]	[1..212]
gi\|226901363, gi... - gi\|237704997\|ref\|ZP_04535478.1\| glycine cleavage system transcriptional repressor [Escherichia sp. 3... gi\|91211811, gi\|... - gi\|91211811\|ref\|YP_541797.1\| glycine cleavage system transcriptional repressor [Escherichia coli UTI...	1.0E-51	[1..212]	[1..212]
gi\|26109255, gi\|... - gi\|26248849\|ref\|NP_754889.1\| Glycine cleavage system transcriptional repressor [Escherichia coli CFT...	2.0E-51	[1..212]	[1..212]
gi\|62181055, gi\|... - gi\|62181055\|ref\|YP_217472.1\| transcriptional repressor of gcv operon [Salmonella enterica subsp. ent...	3.0E-50	[6..212]	[18..224]
gi\|45442459, gi\|... - gi\|45442459\|ref\|NP_993998.1\| Glycine cleavage system regulatory protein [Yersinia pestis biovar Micr...	7.0E-44	[7..208]	[33..235]
gi\|89109285, gi\|... - gi\|89109285\|ref\|AP_003065.1\| DNA-binding transcriptional repressor, regulatory protein accessory to ... EG11149 - transcriptional repressor, regulatory protein accessory to GcvA / Required for repression of gcv ope... gi\|189362257, gi... - gi\|189362257\|gb\|EDU80676.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|238860991, gi... - gi\|238901644\|ref\|YP_002927440.1\| DNA-binding transcriptional repressor, regulatory protein accessory... gi\|189368384, gi... - gi\|189368384\|gb\|EDU86800.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|242378079, gi... - gi\|251785806\|ref\|YP_003000110.1\| hypothetical protein B21_02333 [Escherichia coli BL21], gi\|24237807... gi\|189003241, gi... - gi\|189003241\|gb\|EDU72227.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|168773610, gi... - gi\|187770555\|gb\|EDU34399.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|162138395 - gi\|162138395\|ref\|YP_541797.2\| glycine cleavage system transcriptional repressor [Escherichia coli UT... gi\|254794424, gi... - gi\|254794424\|ref\|YP_003079261.1\| DNA-binding transcriptional repressor, regulatory protein accessory... gi\|161986482 - gi\|161986482\|ref\|YP_311424.2\| glycine cleavage system transcriptional repressor [Shigella sonnei Ss0... gi\|189356644, gi... - gi\|189356644\|gb\|EDU75063.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|254289215, gi... - gi\|254289215\|ref\|YP_003054963.1\| DNA-binding transcriptional repressor, regulatory protein accessory... gi\|168748465, gi... - gi\|188017147\|gb\|EDU55269.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|253974355, gi... - gi\|254162454\|ref\|YP_003045562.1\| DNA-binding transcriptional repressor, regulatory protein accessory... gi\|161367553 - gi\|161367553\|ref\|NP_289032.2\| glycine cleavage system transcriptional repressor [Escherichia coli O1... gi\|161984889 - gi\|161984889\|ref\|YP_408874.2\| glycine cleavage system transcriptional repressor [Shigella boydii Sb2... gi\|161950072 - gi\|161950072\|ref\|YP_404210.2\| glycine cleavage system transcriptional repressor [Shigella dysenteria... GCVR_SHIFL - Glycine cleavage system transcriptional repressor OS=Shigella flexneri GN=gcvR PE=3 SV=2 GCVR_ECOLI - Glycine cleavage system transcriptional repressor (Gcv operon repressor) - Escherichia coli gi\|24052893, gi\|... - gi\|24113808\|ref\|NP_708318.1\| glycine cleavage system transcriptional repressor [Shigella flexneri 2a... gi\|38704091 - gi\|38704091\|ref\|NP_311368.2\| transcriptional regulation of gcv operon [Escherichia coli O157:H7] gi\|124529792, gi... - gi\|124529792\|ref\|ZP_01700669.1\| amino acid-binding ACT domain protein [Escherichia coli B], gi\|12449... gi\|208727563, gi... - gi\|208807762\|ref\|ZP_03250099.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|195936622 - gi\|195936622\|ref\|ZP_03082004.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|208740266, gi... - gi\|208820143\|ref\|ZP_03260463.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|208733251, gi... - gi\|208811974\|ref\|ZP_03253303.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|194427305, gi... - gi\|194427305\|ref\|ZP_03059855.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|192958274, gi... - gi\|193068322\|ref\|ZP_03049285.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|194437552, gi... - gi\|194437552\|ref\|ZP_03069648.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... EG11149 - transcriptional repressor, regulatory protein accessory to GcvA / Required for repression of gcv ope... gi\|194432063, gi... - gi\|194432063\|ref\|ZP_03064352.1\| glycine cleavage system transcriptional repressor [Shigella dysenter... gi\|191167658, gi... - gi\|191167658\|ref\|ZP_03029468.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|170517736, gi... - gi\|170680018\|ref\|YP_001744662.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|193064716, gi... - gi\|193064716\|ref\|ZP_03045794.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|191172895, gi... - gi\|191172895\|ref\|ZP_03034430.1\| glycine cleavage system transcriptional repressor [Escherichia coli ... gi\|189378664, gi... - gi\|189378664\|gb\|EDU97080.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|189372379, gi... - gi\|189372379\|gb\|EDU90795.1\| glycine cleavage system transcriptional repressor [Escherichia coli O157... gi\|170082089, gi... - gi\|170082089\|ref\|YP_001731409.1\| DNA-binding transcriptional repressor, regulatory protein accessory... gi\|169754164, gi... - gi\|170019236\|ref\|YP_001724190.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|218705978, gi... - gi\|218705978\|ref\|YP_002413497.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|218690606, gi... - gi\|218690606\|ref\|YP_002398818.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|218559415, gi... - gi\|218559415\|ref\|YP_002392328.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|218700937, gi... - gi\|218700937\|ref\|YP_002408566.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|218352840, gi... - gi\|218696108\|ref\|YP_002403775.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|215265855, gi... - gi\|215487783\|ref\|YP_002330214.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|38704091 - gi\|38704091\|ref\|NP_311368.2\| glycine cleavage system transcriptional repressor [Escherichia coli O15... gi\|209161088, gi... - gi\|209399688\|ref\|YP_002271948.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|110344245, gi... - gi\|110642653\|ref\|YP_670383.1\| glycine cleavage system transcriptional repressor [Escherichia coli 53... gi\|218361773, gi... - gi\|218555005\|ref\|YP_002387918.1\| glycine cleavage system transcriptional repressor [Escherichia coli... gi\|110615960, gi... - gi\|110806412\|ref\|YP_689932.1\| glycine cleavage system transcriptional repressor [Shigella flexneri 5... gi\|217326854, gi... - gi\|217326854\|ref\|ZP_03442937.1\| glycine cleavage system transcriptional repressor [Escherichia coli ...	9.0E-43	[23..212]	[1..190]
gi\|89104851, gi\|... - gi\|89104851\|ref\|ZP_01177383.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia pestis ... gi\|108780161, gi... - gi\|108808248\|ref\|YP_652164.1\| glycine cleavage system transcriptional repressor [Yersinia pestis Ant... gi\|51597100, gi\|... - gi\|51597100\|ref\|YP_071291.1\| glycine cleavage system transcriptional repressor [Yersinia pseudotuber... Q668F6\|Q668F6_YERPS - Glycine cleavage system transcriptional repressor - Yersinia pseudotuberculosis gi\|108811485, gi... - gi\|108811485\|ref\|YP_647252.1\| glycine cleavage system transcriptional repressor [Yersinia pestis Nep... gi\|186699218, gi... - gi\|186896192\|ref\|YP_001873304.1\| glycine cleavage system transcriptional repressor [Yersinia pseudot... gi\|167424519, gi... - gi\|167424519\|ref\|ZP_02316272.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|170023603, gi... - gi\|170023603\|ref\|YP_001720108.1\| glycine cleavage system transcriptional repressor [Yersinia pseudot... gi\|162351186, gi... - gi\|77636334\|ref\|ZP_00798409.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia pestis ... gi\|117672946, gi... - gi\|77629828\|ref\|ZP_00792414.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia pseudot... gi\|145211138, gi... - gi\|145599442\|ref\|YP_001163518.1\| glycine cleavage system transcriptional repressor [Yersinia pestis ... gi\|166212485, gi... - gi\|166212485\|ref\|ZP_02238520.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|167422708, gi... - gi\|167422708\|ref\|ZP_02314461.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b... gi\|165989903, gi... - gi\|166011225\|ref\|ZP_02232123.1\| glycine cleavage system transcriptional repressor [Yersinia pestis b...	2.0E-42	[9..208]	[1..201]
gi\|77974618 - gi\|77974618\|ref\|ZP_00830157.1\| COG2716: Glycine cleavage system regulatory protein [Yersinia frederi...	5.0E-42	[9..208]	[1..201]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLYAGFFYGF LKITSPLKGI TGLTPSSQHY LVITALGADR PGIVNTITRH VSSCGCNIED  60
   61 SRLAMLGDEF TFIMLLSGTW NAITLIESTL PLKGAELDLL IVMKRTSDRP RPAMPATVWV 120
  121 QVEVADSPHL IERFTALFNS HEMNIAELVS RTQPAEDDKA AQLFIQITAH SPASQNSANI 180
  181 EQAFKALCTE LNAQGSINVV NYSQHDEQDG VK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.30103
Match:	1u8sA
Description:	Crystal structure of putative glycine cleavage system transcriptional repressor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
acetolactate synthase activity	1.81856869558384	bayes_pls_golite062009
transcription regulator activity	1.38296114573583	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	1.0474189646138	bayes_pls_golite062009
catalytic activity	1.01569611874813	bayes_pls_golite062009
nucleic acid binding	0.562543295273244	bayes_pls_golite062009
binding	0.386656911415569	bayes_pls_golite062009
DNA binding	0.376378714748963	bayes_pls_golite062009
transferase activity	0.07375530569672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: