YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16761136
Organism:	Salmonella enterica subsp. enterica serovar Typhi str. CT18
Length:	285 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16761136.

Description	E-value	Query Range	Subject Range
gi\|194451126, gi... - gi\|194451126\|ref\|YP_002046247.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica ... gi\|56412893, gi\|... - gi\|56412893\|ref\|YP_149968.1\| putative esterase [Salmonella enterica subsp. enterica serovar Paratyph... gi\|194401611, gi... - gi\|194442948\|ref\|YP_002041466.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica ... tr\|Q8ZNL5\|Q8ZNL5... - S-formylglutathione hydrolase OS=Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) GN=yei... gi\|205345127, gi... - gi\|205345127\|gb\|EDZ31891.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica serov... gi\|205350541, gi... - gi\|205350541\|gb\|EDZ37172.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica serov... gi\|238912895 - gi\|238912895\|ref\|ZP_04656732.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica s... gi\|205338260, gi... - gi\|205338260\|gb\|EDZ25024.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica serov... gi\|167991127, gi... - gi\|205330572\|gb\|EDZ17336.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica serov... lcl\|NC_016856.1_... - [gene=fghA] [protein=S-formylglutathione hydrolase] [protein_id=YP_005238246.1] [location=2342995..2... gi\|199605657, gi... - gi\|200388559\|ref\|ZP_03215171.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica s... gi\|197249325, gi... - gi\|197249325\|ref\|YP_002147165.1\| S-formylglutathione hydrolase [Salmonella enterica subsp. enterica ...	3.0E-57	[1..285]	[1..285]
ESTD_RAT - S-formylglutathione hydrolase OS=Rattus norvegicus GN=Esd PE=2 SV=1	3.0E-54	[1..276]	[3..280]
gi\|24378638, gi\|... - gi\|24378638\|ref\|NP_720593.1\| putative esterase [Streptococcus mutans UA159], gi\|24376496\|gb\|AAN57899...	4.0E-54	[1..282]	[1..280]
gi\|71145306, gi\|... - gi\|71279566\|ref\|YP_267568.1\| putative esterase [Colwellia psychrerythraea 34H], gi\|71145306\|gb\|AAZ25...	5.0E-54	[1..278]	[7..283]
gi\|78368020, gi\|... - gi\|78368020\|ref\|ZP_00838275.1\| Carboxylesterase [Shewanella sp. PV-4], gi\|78359932\|gb\|EAP01779.1\| Ca...	5.0E-54	[1..276]	[3..276]
gi\|114565208, gi... - gi\|69953478\|ref\|ZP_00640589.1\| Carboxylesterase [Shewanella frigidimarina NCIMB 400], gi\|69163463\|gb...	6.0E-54	[1..276]	[3..278]
gi\|91795111, gi\|... - gi\|91795111\|ref\|YP_564762.1\| carboxylesterase [Shewanella denitrificans OS217], gi\|91717113\|gb\|ABE57...	8.0E-54	[1..277]	[3..279]
gi\|54307978, gi\|... - gi\|54307978\|ref\|YP_128998.1\| putative esterase [Photobacterium profundum SS9], gi\|46912404\|emb\|CAG19...	1.0E-53	[1..276]	[3..279]
gi\|90311105, gi\|... - gi\|90407745\|ref\|ZP_01215923.1\| putative esterase [Psychromonas sp. CNPT3], gi\|90311105\|gb\|EAS39212.1...	1.0E-53	[1..277]	[3..278]
gi\|77381356, gi\|... - gi\|77457353\|ref\|YP_346858.1\| putative esterase [Pseudomonas fluorescens Pf0-1], gi\|77381356\|gb\|ABA72...	1.0E-53	[1..277]	[3..280]

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Predicted Domain #1

Region A:
Residues: [1-285]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEMLEEHRCF GGWQQRWRHH AATLNCAMTF SIFLPPTQDN EPPPVLYWLS GLTCNDENFT  60
   61 TKAGAQRIAA ELGIVLVMPD TSPRGEQVAD DSGYDLGHGA GFYLNATQPP WASHYRMYDY 120
  121 LRDELPALIQ TQFNVSDRCA ISGHSMGGHG ALIMALKNPG KYTSISAFAP IVNPSRVPWG 180
  181 IKALTAYLGE DESAWTEWDS CELMLASQPQ DAIPVLIDQG DSDQFLADQL QPAVLAEAAR 240
  241 QTAWPMTLRI QPGYDHSYYF IASFIEDHLR FHARYLRDEH ETSPT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.522879
Match:	1pv1A
Description:	Crystal Structure Analysis of Yeast Hypothetical Protein: YJG8_YEAST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-formylglutathione hydrolase activity	2.11404818814754	bayes_pls_golite062009
hydrolase activity	1.75934962198703	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	1.09488027320166	bayes_pls_golite062009
phospholipase activity	1.05835015160042	bayes_pls_golite062009
lipase activity	0.849473630399459	bayes_pls_golite062009
carboxylesterase activity	0.424330502936163	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: