YRC Public Data Repository - Protein Structure Prediction

Protein:	CORC_SALTY
Organism:	Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Length:	292 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CORC_SALTY.

Description	E-value	Query Range	Subject Range
gi\|3639065 - gi\|3639065\|gb\|AAC36474.1\| integral membrane protein CorC [Salmonella typhimurium] gi\|3639065\|gb\|AA... - integral membrane protein CorC [Salmonella typhimurium]	2.0E-55	[1..292]	[1..292]
CORC_ECOLI - Magnesium and cobalt efflux protein corC - Escherichia coli gi\|89107527, gi\|... - gi\|89107527\|ref\|AP_001307.1\| predicteed ion transport [Escherichia coli str. K-12 substr. W3110], gi... gi\|81240083, gi\|... - gi\|82775935\|ref\|YP_402282.1\| putative transport protein [Shigella dysenteriae Sd197], gi\|81240083\|gb... gi\|82543102, gi\|... - gi\|82543102\|ref\|YP_407049.1\| putative transport protein [Shigella boydii Sb227], gi\|81244513\|gb\|ABB6... gi\|75209029, gi\|... - gi\|75209029\|ref\|ZP_00709289.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli B1... gi\|75228115, gi\|... - gi\|75228115\|ref\|ZP_00714786.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli B7... gi\|157154891, gi... - gi\|75189696\|ref\|ZP_00702963.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli E2... gi\|254791821, gi... - gi\|254791821\|ref\|YP_003076658.1\| predicted ion transport [Escherichia coli O157:H7 str. TW14359], gi... gi\|157065826, gi... - gi\|75194835\|ref\|ZP_00704905.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli HS... gi\|254160737, gi... - gi\|254160737\|ref\|YP_003043845.1\| predicteed ion transport [Escherichia coli B str. REL606], gi\|25397... gi\|192930924, gi... - gi\|75258606\|ref\|ZP_00730013.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli E2... gi\|253325402, gi... - gi\|254287525\|ref\|YP_003053273.1\| predicted ion transport [Escherichia coli BL21(DE3)], gi\|253976832\|... gi\|73854671, gi\|... - gi\|74311194\|ref\|YP_309613.1\| putative transport protein [Shigella sonnei Ss046], gi\|73854671\|gb\|AAZ8... gi\|242376432, gi... - gi\|251784159\|ref\|YP_002998463.1\| hypothetical protein B21_00617 [Escherichia coli BL21], gi\|24237643... gi\|75236639, gi\|... - gi\|75236639\|ref\|ZP_00720727.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli E1... gi\|238899935, gi... - gi\|238899935\|ref\|YP_002925731.1\| predicteed ion transport [Escherichia coli BW2952], gi\|238863269\|gb... gi\|191173990, gi... - gi\|75237589\|ref\|ZP_00721620.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli F1... gi\|226898583, gi... - gi\|237707373\|ref\|ZP_04537854.1\| magnesium and cobalt efflux protein CorC [Escherichia sp. 3_2_53FAA]... gi\|15829950, gi\|... - gi\|15829950\|ref\|NP_308723.1\| putative transport protein [Escherichia coli O157:H7 str. Sakai], gi\|13... gi\|227838454, gi... - gi\|227884368\|ref\|ZP_04002173.1\| HCC family HlyC/CorC transporter [Escherichia coli 83972], gi\|227838... gi\|110640880, gi... - gi\|110640880\|ref\|YP_668608.1\| magnesium and cobalt efflux protein CorC [Escherichia coli 536], gi\|11... gi\|110614242, gi... - gi\|110804694\|ref\|YP_688214.1\| putative transport protein [Shigella flexneri 5 str. 8401], gi\|1106142... gi\|194421187, gi... - gi\|83584744\|ref\|ZP_00923407.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli 10... gi\|187730106, gi... - gi\|75175875\|ref\|ZP_00696062.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Shigella boydii BS5... gi\|91209701, gi\|... - gi\|91209701\|ref\|YP_539687.1\| putative transport protein [Escherichia coli UTI89], gi\|91071275\|gb\|ABE... EG13654 - putative ion transport / Heat shock protein, putative Co2+ and Mg2+ efflux protein; contains two CBS... CORC_ECO57 - Magnesium and cobalt efflux protein CorC OS=Escherichia coli O157:H7 GN=corC PE=3 SV=1 gi\|168764666, gi... - gi\|189365370\|gb\|EDU83786.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|30040400, gi\|... - gi\|30062155\|ref\|NP_836326.1\| putative transport protein [Shigella flexneri 2a str. 2457T], gi\|300404... gi\|189363369, gi... - gi\|189363369\|gb\|EDU81788.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|12513564, gi\|... - gi\|15800371\|ref\|NP_286383.1\| putative transport protein [Escherichia coli O157:H7 EDL933], gi\|125135... gi\|168777602, gi... - gi\|187767193\|gb\|EDU31037.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... EG13654 - putative ion transport / Heat shock protein, putative Co2+ and Mg2+ efflux protein; contains two CBS... gi\|189002721, gi... - gi\|189002721\|gb\|EDU71707.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|168786507, gi... - gi\|189373537\|gb\|EDU91953.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|168802433, gi... - gi\|189375559\|gb\|EDU93975.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|170020985, gi... - gi\|170020985\|ref\|YP_001725939.1\| transporter-associated region [Escherichia coli ATCC 8739], gi\|1697... gi\|170080338, gi... - gi\|170080338\|ref\|YP_001729658.1\| ion transport [Escherichia coli str. K-12 substr. DH10B], gi\|169888... gi\|168752227, gi... - gi\|188013889\|gb\|EDU52011.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|189354848, gi... - gi\|189354848\|gb\|EDU73267.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 str. ... gi\|217325431, gi... - gi\|217325431\|ref\|ZP_03441515.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 s... gi\|218357306, gi... - gi\|218549765\|ref\|YP_002383556.1\| putative protein involved in divalent ion export [Escherichia fergu... gi\|218359968, gi... - gi\|218553200\|ref\|YP_002386113.1\| putative protein involved in divalent ion export [Escherichia coli ... gi\|218364358, gi... - gi\|218557589\|ref\|YP_002390502.1\| putative protein involved in divalent ion export [Escherichia coli ... gi\|218688475, gi... - gi\|218688475\|ref\|YP_002396687.1\| putative protein involved in divalent ion export [Escherichia coli ... gi\|218694097, gi... - gi\|218694097\|ref\|YP_002401764.1\| putative protein involved in divalent ion export [Escherichia coli ... gi\|218699022, gi... - gi\|218699022\|ref\|YP_002406651.1\| putative protein involved in divalent ion export [Escherichia coli ... gi\|218703991, gi... - gi\|218703991\|ref\|YP_002411510.1\| putative protein involved in divalent ion export [Escherichia coli ... gi\|170520447, gi... - gi\|170682729\|ref\|YP_001742776.1\| magnesium and cobalt efflux protein CorC [Escherichia coli SMS-3-5]... gi\|195939395 - gi\|195939395\|ref\|ZP_03084777.1\| ion transport [Escherichia coli O157:H7 str. EC4024] gi\|117622867, gi... - gi\|117622867\|ref\|YP_851780.1\| putative transport protein [Escherichia coli APEC O1], gi\|115511991\|gb... gi\|208806832, gi... - gi\|208806832\|ref\|ZP_03249169.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 s... gi\|124529693, gi... - gi\|124529693\|ref\|ZP_01700600.1\| transporter-associated region [Escherichia coli B], gi\|124499696\|gb\|... gi\|208815486, gi... - gi\|208815486\|ref\|ZP_03256665.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 s... CORC_SHIFL - Magnesium and cobalt efflux protein CorC OS=Shigella flexneri GN=corC PE=3 SV=1 gi\|208737218, gi... - gi\|208823025\|ref\|ZP_03263343.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 s... CORC_ECOL6 - Magnesium and cobalt efflux protein CorC OS=Escherichia coli O6 GN=corC PE=3 SV=1 gi\|209398266, gi... - gi\|209398266\|ref\|YP_002269293.1\| magnesium and cobalt efflux protein CorC [Escherichia coli O157:H7 ... CORC_ECOL6 - Magnesium and cobalt efflux protein CorC OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UP... gi\|209917920, gi... - gi\|209917920\|ref\|YP_002292004.1\| hypothetical protein ECSE_0729 [Escherichia coli SE11], gi\|20991117... gi\|24112044, gi\|... - gi\|24112044\|ref\|NP_706554.1\| putative transport protein [Shigella flexneri 2a str. 301], gi\|24050867... gi\|215485691, gi... - gi\|215485691\|ref\|YP_002328122.1\| predicted ion transport [Escherichia coli O127:H6 str. E2348/69], g...	4.0E-55	[1..292]	[1..292]
gi\|17134355, gi\|... - gi\|17232708\|ref\|NP_489256.1\| hypothetical protein alr5216 [Nostoc sp. PCC 7120], gi\|17134355\|dbj\|BAB... gi\|25302934 - pir\|\|AH2457 hypothetical protein alr5216 [imported] - Nostoc sp. (strain PCC 7120)	8.0E-55	[6..289]	[153..438]
gi\|115524892, gi... - gi\|77740265\|ref\|ZP_00808753.1\| CBS:IMP dehydrogenase/GMP reductase:Protein of unknown function DUF21...	9.0E-55	[10..287]	[163..439]
gi\|188493543, gi... - gi\|75511303\|ref\|ZP_00733997.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Escherichia coli 53...	1.0E-54	[1..292]	[1..292]
gi\|75702703, gi\|... - gi\|75908978\|ref\|YP_323274.1\| hypothetical protein Ava_2766 [Anabaena variabilis ATCC 29413], gi\|7570...	1.0E-54	[6..289]	[153..438]
gi\|83569118, gi\|... - gi\|83569118\|ref\|ZP_00920578.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Shigella dysenteria...	2.0E-54	[1..292]	[1..292]
gi\|53796489 - ref\|ZP_00357450.1\| COG1253: Hemolysins and related proteins containing CBS domains [Chloroflexus aur... gi\|76167046, gi\|... - gi\|76257960\|ref\|ZP_00765617.1\| CBS:Protein of unknown function DUF21:Transporter-associated region [... gi\|222527343, gi... - gi\|222527343\|ref\|YP_002571814.1\| protein of unknown function DUF21 [Chloroflexus sp. Y-400-fl], gi\|2...	2.0E-53	[10..286]	[153..433]
gi\|238713013, gi... - gi\|77957560\|ref\|ZP_00821612.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Yersinia bercovieri... gi\|238795393, gi... - gi\|77962185\|ref\|ZP_00826009.1\| COG4535: Putative Mg2+ and Co2+ transporter CorC [Yersinia mollaretii...	3.0E-53	[1..292]	[1..292]
gi\|55980703, gi\|... - gi\|55980703\|ref\|YP_144000.1\| hemolysin-related protein [Thermus thermophilus HB8], gi\|55772116\|dbj\|B...	3.0E-53	[25..274]	[179..429]

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Predicted Domain #1

Region A:
Residues: [1-292]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDDNSHSSD TVNSKKGFFS LLLSQLFHGE PKNRDELLAL IRDSGQNELI DEDTRDMLEG  60
   61 VMDIADQRVR DIMIPRSQMI TLKRNQTLDE CLDVIIESAH SRFPVISEDK DHIEGILMAK 120
  121 DLLPFMRSDA EAFSMDKVLR TAVVVPESKR VDRMLKEFRS QRYHMAIVID EFGGVSGLVT 180
  181 IEDILELIVG EIEDEYDEED DIDFRQLSRH TWTIRALASI EDFNDAFGTH FSDEEVDTIG 240
  241 GLVMQAFGHL PARGETIDID GYQFKVAMAD SRRIIQVHVR IPDDSPQPKL DE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.045757
Match:	1zfjA
Description:	Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
magnesium ion transmembrane transporter activity	5.02895256941344	bayes_pls_golite062009
ion transmembrane transporter activity	2.30714747153741	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.05832395284653	bayes_pls_golite062009
metal ion transmembrane transporter activity	1.77666157413171	bayes_pls_golite062009
cation transmembrane transporter activity	1.5512605628205	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	1.46421916456482	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	1.11928485686295	bayes_pls_golite062009
transporter activity	0.666337333933876	bayes_pls_golite062009
transmembrane transporter activity	0.534933550137003	bayes_pls_golite062009
substrate-specific transporter activity	0.26029124809786	bayes_pls_golite062009
anion transmembrane transporter activity	0.0796146522242194	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: