YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16501457, gi\|...
Organism:	Salmonella enterica subsp. enterica serovar Typhi
Length:	220 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16501457, gi|....

Description	E-value	Query Range	Subject Range
gi\|62178741, gi\|... - gi\|62178741\|ref\|YP_215158.1\| putative carbonic anhydrase [Salmonella enterica subsp. enterica serova... gi\|205347482, gi... - gi\|205360728\|ref\|ZP_02685949.2\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar H...	7.0E-74	[1..220]	[18..237]
gi\|194448935, gi... - gi\|194448935\|ref\|YP_002044148.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Hei... gi\|238911231 - gi\|238911231\|ref\|ZP_04655068.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Tenn... gi\|197215082, gi... - gi\|197251379\|ref\|YP_002145170.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar ... gi\|195632738, gi... - gi\|195632738\|gb\|EDX51192.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar Newpo... gi\|194445260, gi... - gi\|194445260\|ref\|YP_002039406.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar ... gi\|168230463, gi... - gi\|205335031\|gb\|EDZ21795.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar Kentu... lcl\|NC_016856.1_... - [gene=yadF] [protein=carbonic anhydrase] [protein_id=YP_005235834.1] [location=complement(202115..20... gi\|205337446, gi... - gi\|205337446\|gb\|EDZ24210.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar Heide... gi\|167550631, gi... - gi\|205324392\|gb\|EDZ12231.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar Saint... gi\|167990050, gi... - gi\|205331331\|gb\|EDZ18095.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar 4,[5]... gi\|16763561, gi\|... - gi\|16763561\|ref\|NP_459176.1\| carbonic anhydrase [Salmonella typhimurium LT2], gi\|16418673\|gb\|AAL1913... gi\|162139620 - gi\|162139620\|ref\|YP_215158.2\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Choler... gi\|206707490, gi... - gi\|207855687\|ref\|YP_002242338.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Ent... gi\|213053559 - gi\|213053559\|ref\|ZP_03346437.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Typh... gi\|200389129, gi... - gi\|200389129\|ref\|ZP_03215741.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar V... gi\|205351512, gi... - gi\|205351512\|ref\|YP_002225313.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Gal... gi\|197240280, gi... - gi\|197262025\|ref\|ZP_03162099.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar S... gi\|198245647, gi... - gi\|198245647\|ref\|YP_002214127.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar ...	3.0E-73	[1..220]	[1..220]
gi\|204323446, gi... - gi\|204926781\|ref\|ZP_03217983.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar J... gi\|197361380, gi... - gi\|197361380\|ref\|YP_002141015.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Par... gi\|194712491, gi... - gi\|194736989\|ref\|YP_002113190.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar ... gi\|205342536, gi... - gi\|205342536\|gb\|EDZ29300.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar Welte... gi\|168234940, gi... - gi\|197291744\|gb\|EDY31094.1\| carbonate dehydratase [Salmonella enterica subsp. enterica serovar Schwa... gi\|161361884, gi... - gi\|161612520\|ref\|YP_001586485.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Par... gi\|56126701, gi\|... - gi\|56412444\|ref\|YP_149519.1\| carbonic anhydrase [Salmonella enterica subsp. enterica serovar Paratyp...	1.0E-72	[1..220]	[1..220]
gi\|81239563, gi\|... - gi\|82775415\|ref\|YP_401762.1\| carbonic anhydrase [Shigella dysenteriae Sd197], gi\|81239563\|gb\|ABB6027...	6.0E-72	[1..220]	[1..220]
gi\|192931097, gi... - gi\|193063189\|ref\|ZP_03044280.1\| carbonic anhydrase [Escherichia coli E22], gi\|192931097\|gb\|EDV83700.... gi\|190903601, gi... - gi\|191166350\|ref\|ZP_03028182.1\| carbonic anhydrase [Escherichia coli B7A], gi\|190903601\|gb\|EDV63318.... gi\|188488347, gi... - gi\|188493148\|ref\|ZP_03000418.1\| carbonic anhydrase [Escherichia coli 53638], gi\|188488347\|gb\|EDU6345... gi\|242375959, gi... - gi\|251783686\|ref\|YP_002997990.1\| hypothetical protein B21_00124 [Escherichia coli BL21], gi\|24237595... CAN_SHIFL - Carbonic anhydrase 2 OS=Shigella flexneri GN=can PE=3 SV=1 gi\|170680677, gi... - gi\|170680677\|ref\|YP_001742253.1\| carbonic anhydrase [Escherichia coli SMS-3-5], gi\|170518395\|gb\|ACB1... gi\|238899525, gi... - gi\|238899525\|ref\|YP_002925321.1\| carbonic anhydrase [Escherichia coli BW2952], gi\|238860108\|gb\|ACR62... gi\|226840649, gi... - gi\|254037543\|ref\|ZP_04871620.1\| carbonic anhydrase [Escherichia sp. 1_1_43], gi\|226840649\|gb\|EEH7265... gi\|215485290, gi... - gi\|215485290\|ref\|YP_002327721.1\| carbonic anhydrase [Escherichia coli O127:H6 str. E2348/69], gi\|215... gi\|209917317, gi... - gi\|209917317\|ref\|YP_002291401.1\| carbonic anhydrase [Escherichia coli SE11], gi\|209910576\|dbj\|BAG756... gi\|254287049, gi... - gi\|254287049\|ref\|YP_003052797.1\| carbonic anhydrase [Escherichia coli BL21(DE3)], gi\|253976356\|gb\|AC... gi\|194439138, gi... - gi\|194439138\|ref\|ZP_03071220.1\| carbonic anhydrase [Escherichia coli 101-1], gi\|194421957\|gb\|EDX3796... gi\|194428330, gi... - gi\|194428330\|ref\|ZP_03060872.1\| carbonic anhydrase [Escherichia coli B171], gi\|194413705\|gb\|EDX29985... gi\|253972147, gi... - gi\|254160246\|ref\|YP_003043354.1\| carbonic anhydrase [Escherichia coli B str. REL606], gi\|253972147\|g... gi\|74310744, gi\|... - gi\|74310744\|ref\|YP_309163.1\| carbonic anhydrase [Shigella sonnei Ss046], gi\|73854221\|gb\|AAZ86928.1\| ... gi\|110613735, gi... - gi\|110804187\|ref\|YP_687707.1\| carbonic anhydrase [Shigella flexneri 5 str. 8401], gi\|110613735\|gb\|AB... gi\|169887598, gi... - gi\|170079763\|ref\|YP_001729083.1\| carbonic anhydrase [Escherichia coli str. K-12 substr. DH10B], gi\|1... gi\|170021520, gi... - gi\|170021520\|ref\|YP_001726474.1\| carbonic anhydrase [Escherichia coli ATCC 8739], gi\|169756448\|gb\|AC... CAN_ECOLI - Carbonic anhydrase 2 (EC 4.2.1.1) - Escherichia coli gi\|89107007, gi\|... - gi\|89107007\|ref\|AP_000787.1\| carbonic anhydrase [Escherichia coli str. K-12 substr. W3110], gi\|85674... EG12319 - carbonic anhydrase / Carbonic anhydrase, beta class gi\|124499115, gi... - gi\|124530588\|ref\|ZP_01701191.1\| Carbonate dehydratase [Escherichia coli B], gi\|124499115\|gb\|EAY46610... gi\|30061691, gi\|... - gi\|30061691\|ref\|NP_835862.1\| carbonic anhydrase [Shigella flexneri 2a str. 2457T], gi\|30039933\|gb\|AA... EG12319 - carbonic anhydrase / Carbonic anhydrase, beta class gi\|218430480, gi... - gi\|218703383\|ref\|YP_002410902.1\| carbonic anhydrase [Escherichia coli UMN026], gi\|218430480\|emb\|CAR1... gi\|218350324, gi... - gi\|218693592\|ref\|YP_002401259.1\| carbonic anhydrase [Escherichia coli 55989], gi\|218350324\|emb\|CAU96... gi\|218359475, gi... - gi\|218552707\|ref\|YP_002385620.1\| carbonic anhydrase [Escherichia coli IAI1], gi\|218359475\|emb\|CAQ970... gi\|218547582, gi... - gi\|218547582\|ref\|YP_002381373.1\| carbonic anhydrase [Escherichia fergusonii ATCC 35469], gi\|21835512... gi\|157065274, gi... - gi\|157159594\|ref\|YP_001456912.1\| carbonic anhydrase [Escherichia coli HS], gi\|157065274\|gb\|ABV04529.... gi\|24050332, gi\|... - gi\|24111569\|ref\|NP_706079.1\| carbonic anhydrase [Shigella flexneri 2a str. 301], gi\|24050332\|gb\|AAN4... gi\|157080836, gi... - gi\|157158806\|ref\|YP_001461294.1\| carbonic anhydrase [Escherichia coli E24377A], gi\|157080836\|gb\|ABV2...	1.0E-71	[1..220]	[1..220]
gi\|82542729, gi\|... - gi\|82542729\|ref\|YP_406676.1\| carbonic anhydrase [Shigella boydii Sb227], gi\|81244140\|gb\|ABB64848.1\| ... gi\|187731778, gi... - gi\|187731778\|ref\|YP_001878933.1\| carbonic anhydrase [Shigella boydii CDC 3083-94], gi\|187428770\|gb\|A...	2.0E-71	[1..220]	[1..220]
gi\|13359586, gi\|... - gi\|15829384\|ref\|NP_308157.1\| carbonic anhydrase [Escherichia coli O157:H7 str. Sakai], gi\|13359586\|d... gi\|25291479, gi\|... - pir\|\|B90645 probable carbonic anhdrase [imported] - Escherichia coli (strain O157:H7, substrain RIM... gi\|15799810, gi\|... - gi\|15799810\|ref\|NP_285822.1\| carbonic anhydrase [Escherichia coli O157:H7 EDL933], gi\|12512841\|gb\|AA... gi\|208739699, gi... - gi\|208819576\|ref\|ZP_03259896.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4042], gi\|208739... gi\|13359586, gi\|... - gi\|15829384\|ref\|NP_308157.1\| putative carbonic anhdrase [Escherichia coli O157:H7], gi\|13359586\|dbj\|... gi\|209160914, gi... - gi\|209399514\|ref\|YP_002268734.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4115], gi\|20916... gi\|217324823, gi... - gi\|217324823\|ref\|ZP_03440907.1\| carbonic anhydrase [Escherichia coli O157:H7 str. TW14588], gi\|21732... gi\|189376389, gi... - gi\|189376389\|gb\|EDU94805.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC508], gi\|168801463\|r... gi\|195938192 - gi\|195938192\|ref\|ZP_03083574.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4024] gi\|208807227, gi... - gi\|208807227\|ref\|ZP_03249564.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4206], gi\|208727... gi\|208813460, gi... - gi\|208813460\|ref\|ZP_03254789.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4045], gi\|208734... gi\|168770404, gi... - gi\|189360665\|gb\|EDU79084.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4486], gi\|168770404\|... gi\|187767815, gi... - gi\|187767815\|gb\|EDU31659.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4196], gi\|168776836\|... gi\|189000475, gi... - gi\|189000475\|gb\|EDU69461.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4076], gi\|168782016\|... gi\|189371071, gi... - gi\|189371071\|gb\|EDU89487.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC869], gi\|168789233\|r... gi\|168752444, gi... - gi\|188013714\|gb\|EDU51836.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4113], gi\|168752444\|... gi\|168755737, gi... - gi\|189357028\|gb\|EDU75447.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4401], gi\|168755737\|... gi\|168764731, gi... - gi\|189365325\|gb\|EDU83741.1\| carbonic anhydrase [Escherichia coli O157:H7 str. EC4501], gi\|168764731\|... gi\|254590661, gi... - gi\|254791261\|ref\|YP_003076098.1\| carbonic anhydrase [Escherichia coli O157:H7 str. TW14359], gi\|2545...	2.0E-71	[1..220]	[1..220]
gi\|26246066, gi\|... - gi\|26246066\|ref\|NP_752105.1\| carbonic anhydrase [Escherichia coli CFT073], gi\|26106463\|gb\|AAN78649.1... gi\|117622413, gi... - gi\|117622413\|ref\|YP_851326.1\| carbonic anhydrase [Escherichia coli APEC O1], gi\|115511537\|gb\|ABI9961... gi\|218557069, gi... - gi\|218557069\|ref\|YP_002389982.1\| carbonic anhydrase [Escherichia coli S88], gi\|218363838\|emb\|CAR0150... gi\|218425568, gi... - gi\|218688004\|ref\|YP_002396216.1\| carbonic anhydrase [Escherichia coli ED1a], gi\|218425568\|emb\|CAR063... gi\|110341937, gi... - gi\|110640345\|ref\|YP_668073.1\| carbonic anhydrase [Escherichia coli 536], gi\|110341937\|gb\|ABG68174.1\|... gi\|191172807, gi... - gi\|191172807\|ref\|ZP_03034344.1\| carbonic anhydrase [Escherichia coli F11], gi\|190906957\|gb\|EDV66559.... gi\|91070768, gi\|... - gi\|91209194\|ref\|YP_539180.1\| carbonic anhydrase [Escherichia coli UTI89], gi\|91070768\|gb\|ABE05649.1\|... gi\|237704282, gi... - gi\|237704282\|ref\|ZP_04534763.1\| yadF [Escherichia sp. 3_2_53FAA], gi\|226902194\|gb\|EEH88453.1\| yadF [... gi\|227838101, gi... - gi\|227884963\|ref\|ZP_04002768.1\| carbonate dehydratase [Escherichia coli 83972], gi\|227838101\|gb\|EEJ4...	2.0E-71	[1..220]	[1..220]
gi\|255055897, gi... - gi\|255055897\|ref\|ZP_05308122.1\| Carbonate dehydratase [Pectobacterium wasabiae WPP163], gi\|254988268... gi\|50122249, gi\|... - gi\|50122249\|ref\|YP_051416.1\| carbonic anhydrase [Pectobacterium atrosepticum SCRI1043], gi\|49612775\|...	7.0E-71	[1..212]	[1..212]
gi\|54310267, gi\|... - gi\|54310267\|ref\|YP_131287.1\| putative carbonic anhydrase [Photobacterium profundum SS9], gi\|46914708...	9.0E-71	[1..214]	[1..214]

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Predicted Domain #1

Region A:
Residues: [1-220]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKDIDTLISN NALWSKMLVE EDPGFFEKLA QAQKPRFLWI GCSDSRVPAE RLTGLEPGEL  60
   61 FVHRNVANLV IHTDLNCLSV VQYAVDALEV EHIIICGHSG CGGIKAAVEN PELGLINNWL 120
  121 LHIRDIWLKH SSLLGKMPEE QRLDALYELN VMEQVYNLGH STIMQSAWKR GQNVTIHGWA 180
  181 YSINDGLLRD LDVTATNRET LENGYHKGIS ALSLKYIPHQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.045757
Match:	1i6oA
Description:	beta-carbonic anhydrase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
carbonate dehydratase activity	2.96380803089124	bayes_pls_golite062009
catalytic activity	1.85658156053797	bayes_pls_golite062009
carbon-oxygen lyase activity	1.691366175135	bayes_pls_golite062009
hydro-lyase activity	1.65497918079842	bayes_pls_golite062009
lyase activity	1.62374861994341	bayes_pls_golite062009
binding	1.32962036184517	bayes_pls_golite062009
protein binding	0.132818074687599	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: