YRC Public Data Repository - Protein Structure Prediction

Protein:	EG10653
Organism:	Escherichia coli K-12
Length:	847 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG10653.

Description	E-value	Query Range	Subject Range
gi\|15833470, gi\|... - gi\|15833470\|ref\|NP_312243.1\| nitrite reductase (NAD(P)H) subunit [Escherichia coli O157:H7 str. Saka... gi\|25391520 - pir\|\|H91155 nitrite reductase (NAD(P)H) subunit [imported] - Escherichia coli (strain O157:H7, subst... gi\|15833470, gi\|... - gi\|15833470\|ref\|NP_312243.1\| nitrite reductase (NAD(P)H) subunit [Escherichia coli O157:H7], gi\|1336...	705.0	[0..1]	[847..1]
gi\|91074417, gi\|... - gi\|91212843\|ref\|YP_542829.1\| nitrite reductase [NAD(P)H] large subunit [Escherichia coli UTI89], gi\|... gi\|110345197, gi... - gi\|110643605\|ref\|YP_671335.1\| nitrite reductase [NAD(P)H] large subunit [Escherichia coli 536], gi\|1... gi\|110616747, gi... - gi\|110807199\|ref\|YP_690719.1\| nitrite reductase (NAD(P)H) subunit [Shigella flexneri 5 str. 8401], g... gi\|170018398, gi... - gi\|170018398\|ref\|YP_001723352.1\| nitrite reductase (NAD(P)H), large subunit [Escherichia coli ATCC 8... gi\|189380140, gi... - gi\|189380140\|gb\|EDU98556.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|195934863 - gi\|195934863\|ref\|ZP_03080245.1\| nitrite reductase (NAD(P)H), large subunit [Escherichia coli O157:H7... gi\|170520970, gi... - gi\|170683252\|ref\|YP_001745614.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli SMS-3-... gi\|208814304, gi... - gi\|208814304\|ref\|ZP_03255633.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7... gi\|208808624, gi... - gi\|208808624\|ref\|ZP_03250961.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7... gi\|209162299, gi... - gi\|209400899\|ref\|YP_002272808.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H... gi\|208821398, gi... - gi\|208821398\|ref\|ZP_03261718.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7... gi\|188492187, gi... - gi\|75516166\|ref\|ZP_00738284.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli 53638], gi\|18849... gi\|188014190, gi... - gi\|188014190\|gb\|EDU52312.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|74313872, gi\|... - gi\|74313872\|ref\|YP_312291.1\| nitrite reductase (NAD(P)H) subunit [Shigella sonnei Ss046], gi\|7385734... gi\|190908192, gi... - gi\|75241539\|ref\|ZP_00725384.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli F11], gi\|1911715... gi\|168759396, gi... - gi\|189369461\|gb\|EDU87877.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|192932649, gi... - gi\|75260345\|ref\|ZP_00731613.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli E22], gi\|1930618... gi\|189358961, gi... - gi\|189358961\|gb\|EDU77380.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|168772737, gi... - gi\|187771762\|gb\|EDU35606.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|189364692, gi... - gi\|189364692\|gb\|EDU83111.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|56383870, gi\|... - gi\|56480319\|ref\|NP_709140.2\| nitrite reductase (NAD(P)H) subunit [Shigella flexneri 2a str. 301], gi... gi\|168785176, gi... - gi\|189374375\|gb\|EDU92791.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|189002552, gi... - gi\|189002552\|gb\|EDU71538.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7 str... gi\|75180020, gi\|... - gi\|75180020\|ref\|ZP_00700007.1\| COG1251: NAD(P)H-nitrite reductase [Shigella boydii BS512], gi\|187733... gi\|117625640, gi... - gi\|117625640\|ref\|YP_858963.1\| nitrite reductase, large subunit, NAD(P)H-binding [Escherichia coli AP... gi\|124528140, gi... - gi\|124528140\|ref\|ZP_01699473.1\| nitrite reductase (NAD(P)H), large subunit [Escherichia coli B], gi\|... gi\|191168417, gi... - gi\|75228406\|ref\|ZP_00715052.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli B7A], gi\|1911684... gi\|75236967, gi\|... - gi\|75236967\|ref\|ZP_00721023.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli E110019], gi\|193... gi\|75188140, gi\|... - gi\|75188140\|ref\|ZP_00701407.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli E24377A], gi\|157... gi\|194427019, gi... - gi\|75211732\|ref\|ZP_00711796.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli B171], gi\|194427... gi\|215266724, gi... - gi\|215488652\|ref\|YP_002331083.1\| nitrite reductase, large subunit, NAD(P)H-binding [Escherichia coli... gi\|209920818, gi... - gi\|209920818\|ref\|YP_002294902.1\| nitrite reductase large subunit [Escherichia coli SE11], gi\|2099140... gi\|26249965, gi\|... - gi\|26249965\|ref\|NP_756005.1\| nitrite reductase [NAD(P)H] large subunit [Escherichia coli CFT073], gi... gi\|218555911, gi... - gi\|218555911\|ref\|YP_002388824.1\| nitrite reductase, large subunit, NAD(P) H-binding [Escherichia col... gi\|30043611, gi\|... - gi\|30065349\|ref\|NP_839520.1\| nitrite reductase (NAD(P)H) subunit [Shigella flexneri 2a str. 2457T], ... gi\|217321964, gi... - gi\|217325743\|ref\|ZP_03441827.1\| nitrite reductase [NAD(P)H], large subunit [Escherichia coli O157:H7... gi\|218353778, gi... - gi\|218697046\|ref\|YP_002404713.1\| nitrite reductase, large subunit, NAD(P) H-binding [Escherichia col... gi\|218429211, gi... - gi\|218691647\|ref\|YP_002399859.1\| nitrite reductase, large subunit, NAD(P) H-binding [Escherichia col... gi\|237703098, gi... - gi\|237703098\|ref\|ZP_04533579.1\| nitrite reductase large subunit [Escherichia sp. 3_2_53FAA], gi\|2269... gi\|254795289, gi... - gi\|254795289\|ref\|YP_003080126.1\| nitrite reductase, large subunit, NAD(P)H-binding [Escherichia coli... gi\|209756768, gi... - gi\|209756776\|gb\|ACI76700.1\| nitrite reductase (NAD(P)H) subunit [Escherichia coli], gi\|209756774\|gb\|...	705.0	[0..1]	[847..1]
gi\|77975031, gi\|... - gi\|77975031\|ref\|ZP_00830568.1\| COG1251: NAD(P)H-nitrite reductase [Yersinia frederiksenii ATCC 33641...	704.0	[0..1]	[842..1]
gi\|81247127, gi\|... - gi\|82545716\|ref\|YP_409663.1\| nitrite reductase (NAD(P)H) subunit [Shigella boydii Sb227], gi\|8124712...	704.0	[0..1]	[847..1]
gi\|16762811 - gi\|16762811\|ref\|NP_458428.1\| nitrite reductase large subunit [Salmonella enterica subsp. enterica se... gi\|213053374 - gi\|213053374\|ref\|ZP_03346252.1\| nitrite reductase large subunit [Salmonella enterica subsp. enterica... gi\|25529467, gi\|... - gi\|25529467\|pir\|\|AG1001 nitrite reductase [NAD(P)H] (EC 1.7.1.4) - Salmonella enterica subsp. enteri... gi\|213426756 - gi\|213426756\|ref\|ZP_03359506.1\| nitrite reductase large subunit [Salmonella enterica subsp. enterica... gi\|29144298, gi\|... - gi\|29144298\|ref\|NP_807640.1\| nitrite reductase large subunit [Salmonella enterica subsp. enterica se... gi\|213864798 - gi\|213864798\|ref\|ZP_03386917.1\| nitrite reductase large subunit [Salmonella enterica subsp. enterica...	704.0	[0..1]	[847..1]
gi\|238727752, gi... - gi\|77978184\|ref\|ZP_00833616.1\| COG1251: NAD(P)H-nitrite reductase [Yersinia intermedia ATCC 29909], ...	704.0	[0..1]	[842..1]
gi\|157162841, gi... - gi\|75197297\|ref\|ZP_00707367.1\| COG1251: NAD(P)H-nitrite reductase [Escherichia coli HS], gi\|15716284...	704.0	[0..1]	[847..1]
gi\|25498730 - pir\|\|E86001 nitrite reductase (NAD(P)H) subunit [imported] - Escherichia coli (strain O157:H7, subst... gi\|15803879, gi\|... - gi\|15803879\|ref\|NP_289913.1\| nitrite reductase (NAD(P)H) subunit [Escherichia coli O157:H7 EDL933], ...	704.0	[0..1]	[847..1]
gi\|77962697, gi\|... - gi\|77962697\|ref\|ZP_00826514.1\| COG1251: NAD(P)H-nitrite reductase [Yersinia mollaretii ATCC 43969], ...	702.0	[0..1]	[842..1]
gi\|56415392, gi\|... - gi\|56415392\|ref\|YP_152467.1\| nitrite reductase large subunit [Salmonella enterica subsp. enterica se... gi\|197095799, gi... - gi\|197364322\|ref\|YP_002143959.1\| nitrite reductase large subunit [Salmonella enterica subsp. enteric...	702.0	[0..1]	[847..1]

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Predicted Domain #1

Region A:
Residues: [1-430]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKVRLAIIG NGMVGHRFIE DLLDKSDAAN FDITVFCEEP RIAYDRVHLS SYFSHHTAEE  60
   61 LSLVREGFYE KHGIKVLVGE RAITINRQEK VIHSSAGRTV FYDKLIMATG SYPWIPPIKG 120
  121 SDTQDCFVYR TIEDLNAIES CARRSKRGAV VGGGLLGLEA AGALKNLGIE THVIEFAPML 180
  181 MAEQLDQMGG EQLRRKIESM GVRVHTSKNT LEIVQEGVEA RKTMRFADGS ELEVDFIVFS 240
  241 TGIRPRDKLA TQCGLDVAPR GGIVINDSCQ TSDPDIYAIG ECASWNNRVF GLVAPGYKMA 300
  301 QVAVDHILGS ENAFEGADLS AKLKLLGVDV GGIGDAHGRT PGARSYVYLD ESKEIYKRLI 360
  361 VSEDNKTLLG AVLVGDTSDY GNLLQLVLNA IELPENPDSL ILPAHSGSGK PSIGVDKLPD 420
  421 SAQICSCFDV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	74.69897
Match:	1ebdA
Description:	Dihydrolipoamide dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on NADH or NADPH	3.16996423124828	bayes_pls_golite062009
oxidoreductase activity	2.84234192551392	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.79314033427747	bayes_pls_golite062009
catalytic activity	1.56773888754354	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.52244283583973	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	0.7514316327505	bayes_pls_golite062009
NADH dehydrogenase activity	0.520416738053292	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [431-743]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKGDLIAAIN KGCHTVAALK AETKAGTGCG GCIPLVTQVL NAELAKQGIE VNNNLCEHFA  60
   61 YSRQELFHLI RVEGIKTFEE LLAKHGKGYG CEVCKPTVGS LLASCWNEYI LKPEHTPLQD 120
  121 SNDNFLANIQ KDGTYSVIPR SPGGEITPEG LMAVGRIARE FNLYTKITGS QRLAMFGAQK 180
  181 DDLPEIWRQL IEAGFETGHA YAKALRMAKT CVGSTWCRYG VGDSVGLGVE LENRYKGIRT 240
  241 PHKMKFGVSG CTRECSEAQG KDVGIIATEK GWNLYVCGNG GMKPRHADLL AADIDRETLI 300
  301 KYLDRFMMFY IRT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	54.0
Match:	2akjA
Description:	Structure of spinach nitrite reductase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on other nitrogenous compounds as donors	4.43988753106114	bayes_pls_golite062009
sulfite reductase (NADPH) activity	3.89379115110861	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	3.13268224304716	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.13576429179797	bayes_pls_golite062009
oxidoreductase activity	2.13548955338201	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.78567689421035	bayes_pls_golite062009
catalytic activity	1.39967796334655	bayes_pls_golite062009

Predicted Domain #3

Region A:
Residues: [744-847]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADKLTRTAPW LENLEGGIDY LKAVIIDDKL GLNAHLEEEM ARLREAVLCE WTETVNTPSA  60
   61 QTRFKHFINS DKRDPNVQMV PEREQHRPAT PYERIPVTLV EDNA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	55.0
Match:	1aopA
Description:	SULFITE REDUCTASE STRUCTURE AT 1.6 ANGSTROM RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on other nitrogenous compounds as donors	4.43988753106114	bayes_pls_golite062009
sulfite reductase (NADPH) activity	3.89379115110861	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	3.13268224304716	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.13576429179797	bayes_pls_golite062009
oxidoreductase activity	2.13548955338201	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	1.78567689421035	bayes_pls_golite062009
catalytic activity	1.39967796334655	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions:

Predicted functions: