YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|49176146, gi\|...
Organism:	Escherichia coli K-12
Length:	219 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|49176146, gi|....

Description	E-value	Query Range	Subject Range
gi\|75227739 - gi\|75227739\|ref\|ZP_00714471.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli B7A] gi\|81245238, gi\|... - gi\|82543827\|ref\|YP_407774.1\| hypothetical protein SBO_1319 [Shigella boydii Sb227], gi\|81245238\|gb\|A... gi\|75177304 - gi\|75177304\|ref\|ZP_00697393.1\| COG1335: Amidases related to nicotinamidase [Shigella boydii BS512]	218.0	[0..1]	[219..1]
gi\|24051771, gi\|... - gi\|24112835\|ref\|NP_707345.1\| hypothetical protein SF1455 [Shigella flexneri 2a str. 301], gi\|2405177... gi\|30062969, gi\|... - gi\|30062969\|ref\|NP_837140.1\| hypothetical protein S1570 [Shigella flexneri 2a str. 2457T], gi\|300412...	217.0	[0..1]	[219..1]
gi\|75190799 - gi\|75190799\|ref\|ZP_00704066.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli E24377A...	217.0	[0..1]	[219..1]
gi\|75256168 - gi\|75256168\|ref\|ZP_00727864.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli E22] gi\|75236765 - gi\|75236765\|ref\|ZP_00720836.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli E110019...	217.0	[0..1]	[219..1]
gi\|73855391, gi\|... - gi\|74311914\|ref\|YP_310333.1\| hypothetical protein SSON_1387 [Shigella sonnei Ss046], gi\|73855391\|gb\|...	216.0	[0..1]	[219..1]
gi\|13361942, gi\|... - gi\|15831729\|ref\|NP_310502.1\| hypothetical protein ECs2475 [Escherichia coli O157:H7], gi\|13361942\|db... gi\|209768360, gi... - pir\|\|G85786 hypothetical protein ydjB [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|12515794, gi\|... - gi\|15802180\|ref\|NP_288202.1\| hypothetical protein Z2802 [Escherichia coli O157:H7 EDL933], gi\|125157... gi\|13361942, gi\|... - gi\|15831729\|ref\|NP_310502.1\| hypothetical protein ECs2475 [Escherichia coli O157:H7 str. Sakai], gi\|...	216.0	[0..1]	[219..1]
gi\|81240933, gi\|... - gi\|82776785\|ref\|YP_403134.1\| hypothetical protein SDY_1505 [Shigella dysenteriae Sd197], gi\|81240933...	215.0	[0..1]	[219..1]
gi\|75513736 - gi\|75513736\|ref\|ZP_00736112.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli 53638] gi\|75195836 - gi\|75195836\|ref\|ZP_00705906.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli HS]	215.0	[0..1]	[219..1]
gi\|75210253 - gi\|75210253\|ref\|ZP_00710421.1\| COG1335: Amidases related to nicotinamidase [Escherichia coli B171]	215.0	[0..1]	[219..1]
gi\|83569625 - gi\|83569625\|ref\|ZP_00921076.1\| COG1335: Amidases related to nicotinamidase [Shigella dysenteriae 101...	214.0	[0..1]	[219..1]

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Predicted Domain #1

Region A:
Residues: [1-219]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIKETVMPPR ALLLVDLQND FCAGGALAVP EGDSTVDVAN RLIDWCQSRG EAVIASQDWH  60
   61 PANHGSFASQ HGVEPYTPGQ LDGLPQTFWP DHCVQNSEGA QLHPLLHQKA IAAVFHKGEN 120
  121 PLVDSYSAFF DNGRRQKTSL DDWLRDHEID ELIVMGLATD YCVKFTVLDA LQLGYKVNVI 180
  181 TDGCRGVNIQ PQDSAHAFME MSAAGATLYT LADWEETQG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.30103
Match:	1ilwA
Description:	Pyrazinamidase/nicotinamidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinamidase activity	2.590271821288	bayes_pls_golite062009
binding	1.80707112356899	bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	1.33901087189475	bayes_pls_golite062009
catalytic activity	0.992051062697807	bayes_pls_golite062009
protein binding	0.343971697425971	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: