YRC Public Data Repository - Protein Structure Prediction

Protein:	3MGH_CLOAB
Organism:	Clostridium acetobutylicum ATCC 824
Length:	205 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for 3MGH_CLOAB.

Description	E-value	Query Range	Subject Range
gi\|219667697, gi... - gi\|219667697\|ref\|YP_002458132.1\| DNA-3-methyladenine glycosylase [Desulfitobacterium hafniense DCB-2...	296.0	[0..2]	[201..17]
3MGH_CLOTE - Putative 3-methyladenine DNA glycosylase OS=Clostridium tetani (strain Massachusetts / E88) GN=CTC_0... 3MGH_CLOTE - Putative 3-methyladenine DNA glycosylase OS=Clostridium tetani GN=CTC_01030 PE=3 SV=1	295.0	[0..1]	[201..1]
3MGH_DESHY - Putative 3-methyladenine DNA glycosylase OS=Desulfitobacterium hafniense (strain Y51) GN=DSY3705 PE=...	294.0	[0..2]	[201..3]
3MGH_ALKOO - Putative 3-methyladenine DNA glycosylase OS=Alkaliphilus oremlandii (strain OhILAs) GN=Clos_1158 PE=...	294.0	[0..1]	[201..1]
3MGH_BACAC - Putative 3-methyladenine DNA glycosylase OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN=BAMEG... 3MGH_BACAA - Putative 3-methyladenine DNA glycosylase OS=Bacillus anthracis (strain A0248) GN=BAA_0975 PE=3 SV=1 gi\|254682934 - gi\|254682934\|ref\|ZP_05146795.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. CNEVA-9066] gi\|254725722 - gi\|254725722\|ref\|ZP_05187504.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. A1055] gi\|254740004 - gi\|254740004\|ref\|ZP_05197696.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. Kruger B] gi\|254753343 - gi\|254753343\|ref\|ZP_05205379.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. Vollum] gi\|254758441 - gi\|254758441\|ref\|ZP_05210468.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. Australia 9... gi\|167635901, gi... - gi\|167635901\|ref\|ZP_02394209.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis str.... gi\|165871895, gi... - gi\|165871895\|ref\|ZP_02216537.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis str.... 3MGH_BACAN - Putative 3-methyladenine DNA glycosylase OS=Bacillus anthracis GN=BA_0869 PE=3 SV=1 gi\|49183850, gi\|... - gi\|49183850\|ref\|YP_027102.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. Sterne], gi\|49... gi\|170668376, gi... - gi\|170687563\|ref\|ZP_02878779.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis str.... gi\|47526157, gi\|... - gi\|47526157\|ref\|YP_017506.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. 'Ames Ancestor... gi\|167513147, gi... - gi\|167639017\|ref\|ZP_02397291.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis str.... gi\|30254619, gi\|... - gi\|30261005\|ref\|NP_843382.1\| 3-methyladenine DNA glycosylase [Bacillus anthracis str. Ames], gi\|3025... gi\|172081096, gi... - gi\|177653868\|ref\|ZP_02935940.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis str.... gi\|21398825, gi\|... - gi\|65318282\|ref\|ZP_00391241.1\| COG2094: 3-methyladenine DNA glycosylase [Bacillus anthracis str. A20... gi\|170708310, gi... - gi\|170708310\|ref\|ZP_02898755.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis str.... gi\|196035178, gi... - gi\|196035178\|ref\|ZP_03102584.1\| methylpurine-DNA glycosylase family protein [Bacillus cereus W], gi\|... gi\|190562173, gi... - gi\|190566621\|ref\|ZP_03019538.1\| methylpurine-DNA glycosylase family protein [Bacillus anthracis Tsia... 3MGH_BACC0 - Putative 3-methyladenine DNA glycosylase OS=Bacillus cereus (strain AH820) GN=BCAH820_0960 PE=3 SV=1	284.0	[0..1]	[201..1]
gi\|47564817, gi\|... - gi\|47564817\|ref\|ZP_00235861.1\| DNA-3-methyladenine glycosylase [Bacillus cereus G9241], gi\|47558190\|... gi\|229154573, gi... - gi\|229154573\|ref\|ZP_04282690.1\| 3-methyladenine DNA glycosylase [Bacillus cereus ATCC 4342], gi\|2286...	283.0	[0..1]	[201..1]
3MGH_BACCZ - Putative 3-methyladenine DNA glycosylase OS=Bacillus cereus (strain ZK / E33L) GN=BCE33L0774 PE=3 SV...	283.0	[0..1]	[201..1]
3MGH_BACWK - Putative 3-methyladenine DNA glycosylase OS=Bacillus weihenstephanensis (strain KBAB4) GN=BcerKBAB4_...	282.0	[0..1]	[201..1]
3MGH_CLOPE - Putative 3-methyladenine DNA glycosylase OS=Clostridium perfringens GN=CPE2576 PE=3 SV=1 gi\|168213504, gi... - gi\|170715064\|gb\|EDT27246.1\| DNA-3-methyladenine glycosylase [Clostridium perfringens CPE str. F4969]... 3MGH_CLOPE - Putative 3-methyladenine DNA glycosylase OS=Clostridium perfringens (strain 13 / Type A) GN=CPE2576 ...	281.0	[0..1]	[201..1]
3MGH_BACC1 - Putative 3-methyladenine DNA glycosylase OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=BCE_095...	281.0	[0..1]	[201..1]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLIREFYSR DTIVVAKELL GKVLVHEVNG IRTSGKIVEV EAYRGINDKG AHAYGGRRTP  60
   61 RTEALYGPAG HAYVYFIYGL YYCMNVVAMQ EGIPEGVLIR AIEPIEGIEV MSERRFKKLF 120
  121 NDLTKYQLKN LTNGPSKLCS AMEIRREQNL MDLNGDELYI EEGKNESFEI VEAKRVGIDY 180
  181 AEEAKDYLWR FYIKGNKCVS VLKKD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.30103
Match:	1f4rA
Description:	3-methyladenine DNA glycosylase (AAG, ANPG, MPG)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
DNA N-glycosylase activity	2.82903690025185	bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds	2.47858881161269	bayes_pls_golite062009
alkylbase DNA N-glycosylase activity	1.38670970810513	bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds	1.31512600331117	bayes_pls_golite062009
catalytic activity	1.11092890710142	bayes_pls_golite062009
hydrolase activity	0.47210507650617	bayes_pls_golite062009
binding	0.0371188365761971	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: