YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|25500476
Organism:	Clostridium acetobutylicum
Length:	122 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|25500476.

Description	E-value	Query Range	Subject Range
gi\|125975181, gi... - gi\|67916939\|ref\|ZP_00510624.1\| PemK-like protein [Clostridium thermocellum ATCC 27405], gi\|67849109\|... gi\|196254205, gi... - gi\|196254205\|ref\|ZP_03152772.1\| transcriptional modulator of MazE/toxin, MazF [Clostridium thermocel...	154.0	[0..3]	[118..1]
gi\|20808550 - gi\|20808550\|ref\|NP_623721.1\| Growth inhibitor [Thermoanaerobacter tengcongensis MB4] gi\|20517176, gi\|... - gi\|20808550\|ref\|NP_623721.1\| growth inhibitor [Thermoanaerobacter tengcongensis MB4], gi\|20517176\|gb...	152.0	[0..1]	[117..1]
gi\|167036913, gi... - gi\|76796513\|ref\|ZP_00778873.1\| PemK-like protein [Thermoanaerobacter ethanolicus ATCC 33223], gi\|765... gi\|167039618, gi... - gi\|167039618\|ref\|YP_001662603.1\| transcriptional modulator of MazE/toxin, MazF [Thermoanaerobacter s... gi\|242230427, gi... - gi\|242258050\|ref\|ZP_04802887.1\| transcriptional modulator of MazE/toxin, MazF [Thermoanaerobacter sp... gi\|241903946, gi... - gi\|241903946\|ref\|ZP_04788660.1\| transcriptional modulator of MazE/toxin, MazF [Thermoanaerobacter br...	152.0	[0..3]	[117..1]
gi\|149951696, gi... - gi\|77686610\|ref\|ZP_00801948.1\| PemK-like protein [Alkaliphilus metalliredigenes QYMF], gi\|77637584\|g...	144.0	[0..3]	[117..1]
gi\|255316165 - gi\|255316165\|ref\|ZP_05357748.1\| putative regulator of cell growth [Clostridium difficile QCD-76w55] gi\|255518826 - gi\|255518826\|ref\|ZP_05386502.1\| putative regulator of cell growth [Clostridium difficile QCD-97b34] gi\|90572757, gi\|... - gi\|90572757\|ref\|ZP_01229280.1\| hypothetical protein CdifQ_02003809 [Clostridium difficile QCD-32g58]... gi\|255652005 - gi\|255652005\|ref\|ZP_05398907.1\| putative regulator of cell growth [Clostridium difficile QCD-37x79] gi\|126701084, gi... - gi\|126701084\|ref\|YP_001089981.1\| putative regulator of cell growth [Clostridium difficile 630], gi\|1... gi\|255657415 - gi\|255657415\|ref\|ZP_05402824.1\| putative regulator of cell growth [Clostridium difficile QCD-23m63] gi\|254977085 - gi\|254977085\|ref\|ZP_05273557.1\| putative regulator of cell growth [Clostridium difficile QCD-66c26] gi\|255094413 - gi\|255094413\|ref\|ZP_05323891.1\| putative regulator of cell growth [Clostridium difficile CIP 107932] gi\|255102670 - gi\|255102670\|ref\|ZP_05331647.1\| putative regulator of cell growth [Clostridium difficile QCD-63q42] gi\|255308491 - gi\|255308491\|ref\|ZP_05352662.1\| putative regulator of cell growth [Clostridium difficile ATCC 43255]	144.0	[0..5]	[115..7]
gi\|255332966, gi... - gi\|255332966\|ref\|ZP_05373956.1\| transcriptional modulator of MazE/toxin, MazF [Geobacillus sp. Y4.1M... gi\|229329495, gi... - gi\|229499569\|ref\|ZP_04393252.1\| transcriptional modulator of MazE/toxin, MazF [Geobacillus sp. Y412M... gi\|220709396, gi... - gi\|221086399\|ref\|ZP_03555941.1\| transcriptional modulator of MazE/toxin, MazF [Geobacillus sp. Y412M... gi\|56418768, gi\|... - gi\|56418768\|ref\|YP_146086.1\| hypothetical protein GK0233 [Geobacillus kaustophilus HTA426], gi\|56378... gi\|212638048, gi... - gi\|212638048\|ref\|YP_002314568.1\| Toxin-antitoxin addiction module toxin component MazF (an endoRNAse... gi\|134265396, gi... - gi\|138893883\|ref\|YP_001124336.1\| transcriptional regulator PemK family [Geobacillus thermodenitrific... gi\|196250543, gi... - gi\|196250543\|ref\|ZP_03149233.1\| transcriptional modulator of MazE/toxin, MazF [Geobacillus sp. G11MC... gi\|239806078, gi... - gi\|239825785\|ref\|YP_002948409.1\| transcriptional modulator of MazE/toxin, MazF [Geobacillus sp. WCH7...	144.0	[0..3]	[117..1]
gi\|110683565, gi... - gi\|110803064\|ref\|YP_697615.1\| PemK family protein [Clostridium perfringens SM101], gi\|110683565\|gb\|A...	143.0	[0..5]	[116..6]
gi\|89085884, gi\|... - gi\|89099498\|ref\|ZP_01172374.1\| hypothetical protein B14911_20010 [Bacillus sp. NRRL B-14911], gi\|890...	142.0	[0..3]	[115..1]
gi\|182626825, gi... - gi\|182626825\|ref\|ZP_02954562.1\| PemK family protein [Clostridium perfringens D str. JGS1721], gi\|177... gi\|169297774, gi... - gi\|169344039\|ref\|ZP_02865027.1\| PemK family protein [Clostridium perfringens C str. JGS1495], gi\|169... gi\|168216616, gi... - gi\|182381298\|gb\|EDT78777.1\| PemK family protein [Clostridium perfringens NCTC 8239], gi\|168216616\|re... gi\|168212786, gi... - gi\|170715819\|gb\|EDT28001.1\| PemK family protein [Clostridium perfringens CPE str. F4969], gi\|1682127... gi\|110799555, gi... - gi\|110799555\|ref\|YP_694751.1\| PemK family protein [Clostridium perfringens ATCC 13124], gi\|110674202... gi\|170711494, gi... - gi\|170711494\|gb\|EDT23676.1\| PemK family protein [Clostridium perfringens B str. ATCC 3626], gi\|16821... gi\|18309277, gi\|... - gi\|18309277\|ref\|NP_561211.1\| PemK family protein [Clostridium perfringens str. 13], gi\|18143953\|dbj\|... gi\|170661214, gi... - gi\|170661214\|gb\|EDT13897.1\| PemK family protein [Clostridium perfringens E str. JGS1987], gi\|1682074...	142.0	[0..5]	[116..6]
gi\|77995807, gi\|... - gi\|78043692\|ref\|YP_359570.1\| PemK family regulatory protein [Carboxydothermus hydrogenoformans Z-290...	142.0	[0..3]	[115..1]

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Predicted Domain #1

Region A:
Residues: [1-122]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTIVVKRGDI FYADLSPVVG SEQGGIRPVI IIQNDMGNKY SPTVIVAAIT SQINKAKLPT  60
   61 HVEISSEDYG LNKDSVVLLE QIRTLDKRRL KEKIGHMTDM DMKKVDEALL ISIGLQNMFE 120
  121 SV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	33.69897
Match:	1ne8A
Description:	PemK-like protein YdcE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transcription regulator activity	1.6695513763642	bayes_pls_golite062009
nucleic acid binding	1.29845490386609	bayes_pls_golite062009
DNA binding	1.250225226827	bayes_pls_golite062009
binding	1.07332947937787	bayes_pls_golite062009
transcription factor activity	1.06504946809994	bayes_pls_golite062009
catalytic activity	0.705204990122558	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: