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View Structure Prediction Details

Protein: gi|2635373, gi|1...
Organism: Bacillus subtilis subsp. subtilis str. 168
Length: 278 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2635373, gi|1....

Description E-value Query
Range
Subject
Range
FPG_BACSU - Formamidopyrimidine-DNA glycosylase OS=Bacillus subtilis GN=mutM PE=3 SV=4
gi|221315175 - gi|221315175|ref|ZP_03596980.1| formamidopyrimidine-DNA glycosylase [Bacillus subtilis subsp. subtil...
FPG_BACSU - Formamidopyrimidine-DNA glycosylase OS=Bacillus subtilis (strain 168) GN=mutM PE=3 SV=4
gi|221324374 - gi|221324374|ref|ZP_03605668.1| formamidopyrimidine-DNA glycosylase [Bacillus subtilis subsp. subtil...
gi|221320092 - gi|221320092|ref|ZP_03601386.1| formamidopyrimidine-DNA glycosylase [Bacillus subtilis subsp. subtil...
369.0 [0..3] [278..1]

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Predicted Domain #1
Region A:
Residues: [1-278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDVPELPEVE TVRRTLTGLV KGKTIKSVEI RWPNIIKRPA EPEEFARKLA GETIQSIGRR  60
   61 GKFLLFHLDH YVMVSHLRME GKYGLHQAEE PDDKHVHVIF TMTDGTQLRY RDVRKFGTMH 120
  121 LFKPGEEAGE LPLSQLGPEP DAEEFTSAYL KDRLAKTNRA VKTALLDQKT VVGLGNIYVD 180
  181 EALFRAGVHP ETKANQLSDK TIKTLHAEIK NTLQEAIDAG GSTVRSYINS QGEIGMFQLQ 240
  241 HFVYGKKDEP CKNCGTMISK IVVGGRGTHF CAKCQTKK

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 94.69897
Match: 1l1tA
Description: DNA repair protein MutM (Fpg)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
DNA N-glycosylase activity 4.06377793944255 bayes_pls_golite062009
oxidized base lesion DNA N-glycosylase activity 3.68895100180378 bayes_pls_golite062009
hydrolase activity, hydrolyzing N-glycosyl compounds 3.63831813037192 bayes_pls_golite062009
oxidized purine base lesion DNA N-glycosylase activity 3.50273405950314 bayes_pls_golite062009
DNA-(apurinic or apyrimidinic site) lyase activity 3.32722481172627 bayes_pls_golite062009
hydrolase activity, acting on glycosyl bonds 2.59048389792519 bayes_pls_golite062009
hydrolase activity 1.74627738237592 bayes_pls_golite062009
binding 1.7313696856499 bayes_pls_golite062009
DNA binding 1.22619720972604 bayes_pls_golite062009
nucleic acid binding 1.17199530230795 bayes_pls_golite062009
transcription regulator activity 1.16376707327858 bayes_pls_golite062009
protein binding 1.14219782236887 bayes_pls_golite062009
transcription factor activity 0.472763834470731 bayes_pls_golite062009
catalytic activity 0.101795606736461 bayes_pls_golite062009
lyase activity 0.0836281676510939 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle