YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11355792
Organism:	Vibrio cholerae
Length:	247 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11355792.

Description	E-value	Query Range	Subject Range
gi\|255744397\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholera CIRS 101] gi\|75827887 - gi\|75827887\|ref\|ZP_00757322.1\| COG0678: Peroxiredoxin [Vibrio cholerae O395] tr\|A0A085R3Z6\|A0... - Hybrid peroxiredoxin hyPrx5 OS=Vibrio cholerae GN=DN30_1754 PE=4 SV=1 gi\|75830057, gi\|... - gi\|75830057\|ref\|ZP_00759342.1\| COG0678: Peroxiredoxin [Vibrio cholerae MO10], gi\|116190632\|ref\|ZP_01... gi\|116219574, gi... - gi\|75818991\|ref\|ZP_00749098.1\| COG0678: Peroxiredoxin [Vibrio cholerae V51], gi\|116219574\|ref\|ZP_014... gi\|262158493\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholerae INDRE 91/1] gi\|75822900, gi\|... - gi\|75822900\|ref\|ZP_00752452.1\| COG0678: Peroxiredoxin [Vibrio cholerae RC385], gi\|116216129\|ref\|ZP_0... gi\|75816566 - gi\|75816566\|ref\|ZP_00747032.1\| COG0678: Peroxiredoxin [Vibrio cholerae V52] gi\|262170114\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC27]	188.0	[0..5]	[247..1]
gi\|38488593 - gi\|38488593\|dbj\|BAD02311.1\| peroxiredoxin like protein [Actinobacillus actinomycetemcomitans]	188.0	[0..2]	[247..8]
gi\|33151875, gi\|... - gi\|33151875\|ref\|NP_873228.1\| putative peroxiredoxin/glutaredoxin family protein [Haemophilus ducreyi...	186.0	[0..1]	[247..1]
gi\|186893469, gi... - gi\|186893469\|ref\|YP_001870581.1\| glutaredoxin family protein [Yersinia pseudotuberculosis PB1/+], gi... gi\|170026287, gi... - gi\|170026287\|ref\|YP_001722792.1\| glutaredoxin family protein [Yersinia pseudotuberculosis YPIII], gi... gi\|229695978, gi... - gi\|229839612\|ref\|ZP_04459771.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis ... gi\|229691036, gi... - gi\|229841697\|ref\|ZP_04461853.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis ... gi\|229896701, gi... - gi\|229896701\|ref\|ZP_04511866.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis ... Q66G63\|Q66G63_YERPS - Putative peroxiredoxin/glutaredoxin family protein - Yersinia pseudotuberculosis gi\|165919612, gi... - gi\|165928382\|ref\|ZP_02224214.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis biovar Orientalis str. ... gi\|166213757, gi... - gi\|166213757\|ref\|ZP_02239792.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis biovar Antiqua str. B42... gi\|165991426, gi... - gi\|166009504\|ref\|ZP_02230402.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis biovar Antiqua str. E19... gi\|167420978, gi... - gi\|167420978\|ref\|ZP_02312731.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis biovar Orientalis str. ... gi\|167401355, gi... - gi\|167401355\|ref\|ZP_02306855.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis biovar Antiqua str. UG0... gi\|167467890 - gi\|167467890\|ref\|ZP_02332594.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis FV-1] gi\|167425931, gi... - gi\|167425931\|ref\|ZP_02317684.1\| hybrid peroxiredoxin hyPrx5 [Yersinia pestis biovar Mediaevalis str.... gi\|218930916, gi... - gi\|218930916\|ref\|YP_002348791.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis... gi\|165915226, gi... - gi\|89102385\|ref\|ZP_01175023.1\| COG0678: Peroxiredoxin [Yersinia pestis biovar Orientalis str. IP275]... gi\|108806104, gi... - gi\|108806104\|ref\|YP_650020.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis An... gi\|108810217, gi... - gi\|229904749\|ref\|ZP_04519860.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis ... gi\|270488732\|ref... - glutaredoxin [Yersinia pestis KIM D27] gi\|149290529, gi... - gi\|150261121\|ref\|ZP_01917849.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis ... gi\|145212471, gi... - gi\|145600775\|ref\|YP_001164851.1\| peroxiredoxin/glutaredoxin family protein [Yersinia pestis Pestoide... gi\|21957000, gi\|... - gi\|22124236\|ref\|NP_667659.1\| peroxiredoxin family protein [Yersinia pestis KIM], gi\|21957000\|gb\|AAM8... gi\|25347426 - pir\|\|AB0477 probable peroxiredoxin/glutaredoxin family protein YPO3916 [imported] - Yersinia pestis ... gi\|51587759, gi\|... - gi\|51594477\|ref\|YP_068668.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pseudotube... gi\|45437753, gi\|... - gi\|45442886\|ref\|NP_994425.1\| putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis bio... gi\|77633924, gi\|... - gi\|77633924\|ref\|ZP_00796037.1\| COG0678: Peroxiredoxin [Yersinia pestis Angola], gi\|162419256\|ref\|YP_... gi\|152960856, gi... - gi\|77630801\|ref\|ZP_00793387.1\| COG0678: Peroxiredoxin [Yersinia pseudotuberculosis IP 31758], gi\|153... gi\|294505566\|ref... - putative peroxiredoxin/glutaredoxin family protein [Yersinia pestis Z176003]	184.0	[0..5]	[245..1]
gi\|32034501 - gi\|32034501\|ref\|ZP_00134673.1\| COG0678: Peroxiredoxin [Actinobacillus pleuropneumoniae serovar 1 str...	184.0	[0..1]	[247..1]
gi\|91188685, gi\|... - gi\|91227291\|ref\|ZP_01261716.1\| peroxiredoxin family protein/glutaredoxin [Vibrio alginolyticus 12G01...	184.0	[0..5]	[245..1]
gi\|46911913, gi\|... - gi\|54307493\|ref\|YP_128513.1\| putative peroxiredoxin/glutaredoxin family protein [Photobacterium prof...	184.0	[0..5]	[245..1]
gi\|90325375, gi\|... - gi\|90413602\|ref\|ZP_01221592.1\| Putative peroxiredoxin/glutaredoxin family protein [Photobacterium pr...	184.0	[0..5]	[245..1]
gi\|238794892, gi... - gi\|77976811\|ref\|ZP_00832281.1\| COG0678: Peroxiredoxin [Yersinia intermedia ATCC 29909], gi\|238794892...	183.0	[0..5]	[245..1]
gi\|77961064, gi\|... - gi\|77961064\|ref\|ZP_00824912.1\| COG0678: Peroxiredoxin [Yersinia mollaretii ATCC 43969], gi\|238798323...	183.0	[0..5]	[245..1]

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Predicted Domain #1

Region A:
Residues: [1-247]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRNTMFTSKE GQTIPQVTFP TRQGDAWVNV TSDELFKGKT VIVFSLPGAF TPTCSSTHLP  60
   61 RYNELFPVFK EHGVDSILCV SVNDTFVMNA WKDDQNADNI TFIPDGNGEF TDGMGMLVDK 120
  121 NDLGFGKRSW RYSMLVKDGV VEKMFIEPNE PGDPFKVSDA DTMLKYIAPQ YKVQESVTIF 180
  181 TKPGCPYCAK AKQALIDAGL QYEELILGKD ATTVSLRAVS GRTTVPQVFI GGKHIGGSDD 240
  241 LEVYLNQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.154902
Match:	1nm3A
Description:	C-terminal, Grx domain of Hybrid-Prx5; N-terminal, Prx domain of Hybrid-Prx5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
selenium binding	1.1082524159827	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.52671047749426	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: