YRC Public Data Repository - Protein Structure Prediction

Protein:	SLYD_VIBCH
Organism:	Vibrio cholerae O1 biovar El Tor str. N16961
Length:	201 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SLYD_VIBCH.

Description	E-value	Query Range	Subject Range
SLYD_PASMU - FKBP-type peptidyl-prolyl cis-trans isomerase SlyD OS=Pasteurella multocida (strain Pm70) GN=slyD PE... SLYD_PASMU - FKBP-type peptidyl-prolyl cis-trans isomerase slyD OS=Pasteurella multocida GN=slyD PE=1 SV=1	177.0	[0..1]	[198..1]
gi\|153840033, gi... - gi\|153840033\|ref\|ZP_01992700.1\| fkbp-type peptidyl-prolyl cis-trans isomerase slyd [Vibrio parahaemo... gi\|28899557, gi\|... - gi\|28899557\|ref\|NP_799162.1\| peptidyl-prolyl cis-trans isomerase, FKBP-type [Vibrio parahaemolyticus... gi\|28807793 - gi\|28807793\|dbj\|BAC61046.1\| peptidyl-prolyl cis-trans isomerase, FKBP-type [Vibrio parahaemolyticus ...	164.0	[0..1]	[183..1]
gi\|33147672, gi\|... - gi\|33151452\|ref\|NP_872805.1\| FkbP-type peptidyl-prolyl cis-trans isomerase [Haemophilus ducreyi 3500...	163.0	[0..1]	[201..1]
gi\|227119043, gi... - gi\|75827855\|ref\|ZP_00757290.1\| COG1047: FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Vibrio cho...	162.0	[0..1]	[165..1]
gi\|37199976, gi\|... - gi\|37681225\|ref\|NP_935834.1\| FKBP-type peptidyl-prolyl cis-trans isomerase 2 [Vibrio vulnificus YJ01...	162.0	[0..1]	[154..14]
gi\|84390796, gi\|... - gi\|84390796\|ref\|ZP_00991488.1\| peptidyl-prolyl cis-trans isomerase, FKBP-type [Vibrio splendidus 12B...	160.0	[0..1]	[165..1]
gi\|218323782, gi... - gi\|218710763\|ref\|YP_002418384.1\| SlpA protein [Vibrio splendidus LGP32], gi\|218323782\|emb\|CAV20139.1... gi\|85834916, gi\|... - gi\|86147351\|ref\|ZP_01065665.1\| peptidyl-prolyl cis-trans isomerase, FKBP-type [Vibrio sp. MED222], g...	160.0	[0..1]	[167..1]
gi\|116183326, gi... - gi\|75853782\|ref\|ZP_00761545.1\| COG1047: FKBP-type peptidyl-prolyl cis-trans isomerases 2 [Vibrio sp....	159.0	[0..1]	[165..1]
gi\|27360871, gi\|... - gi\|27364726\|ref\|NP_760254.1\| FKBP-type peptidyl-prolyl cis-trans isomerase 2 [Vibrio vulnificus CMCP...	159.0	[0..1]	[154..1]
gi\|84509178, gi\|... - gi\|84517060\|ref\|ZP_01004417.1\| peptidyl-prolyl cis-trans isomerase, FKBP-type [Loktanella vestfolden...	158.0	[0..3]	[142..4]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIEKNTVAS LAYQLTIEDG VVVDQSTVDA PLDYLHGHNN LITGLERELE GKVAGDKFTV  60
   61 TIAPEDAYGE HNEDLVQRVP ADVFQGVDEL EVGMRFLADT DQGPIPVEIT EVDGDEVVVD 120
  121 GNHMLAGQSL TFTVEVVAVR AATEDEIAHG HIHQAGGCGH DHDHDHDHEG GCCGGEGHGH 180
  181 DHHGHGKKEG GCCGGGGCGS H

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.69897
Match:	1ix5A
Description:	Archaeal FKBP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidyl-prolyl cis-trans isomerase activity	4.4182664267098	bayes_pls_golite062009
cis-trans isomerase activity	4.33661522951196	bayes_pls_golite062009
isomerase activity	2.83057106437196	bayes_pls_golite062009
macrolide binding	1.34183721806994	bayes_pls_golite062009
catalytic activity	1.25572252987503	bayes_pls_golite062009
FK506 binding	1.11705415888427	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: