YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11265841
Organism:	Vibrio cholerae
Length:	298 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11265841.

Description	E-value	Query Range	Subject Range
gi\|153826891, gi... - gi\|153826891\|ref\|ZP_01979558.1\| signal peptidase I [Vibrio cholerae MZO-2], gi\|149739254\|gb\|EDM53516... gi\|153214494, gi... - gi\|153214494\|ref\|ZP_01949403.1\| signal peptidase I [Vibrio cholerae 1587], gi\|124115296\|gb\|EAY34116.... gi\|125621220, gi... - gi\|75818648\|ref\|ZP_00748784.1\| COG0681: Signal peptidase I [Vibrio cholerae V51], gi\|254226247\|ref\|Z... tr\|D7HEM9\|D7HEM9... - Signal peptidase I OS=Vibrio cholerae GN=lepB PE=3 SV=1, Signal peptidase I OS=Vibrio cholerae RC385... gi\|229338030, gi... - gi\|229524449\|ref\|ZP_04413854.1\| signal peptidase I [Vibrio cholerae bv. albensis VL426], gi\|22933803... gi\|229521289, gi... - gi\|229521289\|ref\|ZP_04410709.1\| signal peptidase I [Vibrio cholerae TM 11079-80], gi\|229341821\|gb\|EE... gi\|229335467, gi... - gi\|229527070\|ref\|ZP_04416465.1\| signal peptidase I [Vibrio cholerae 12129(1)], gi\|229335467\|gb\|EEO00...	331.0	[0..1]	[298..1]
gi\|84376757, gi\|... - gi\|84390103\|ref\|ZP_00991365.1\| Signal peptidase I [Vibrio splendidus 12B01], gi\|84376757\|gb\|EAP93632...	321.0	[0..1]	[298..1]
gi\|27361079, gi\|... - gi\|27364933\|ref\|NP_760461.1\| Signal peptidase I [Vibrio vulnificus CMCP6], gi\|27361079\|gb\|AAO09988.1... gi\|37199766, gi\|... - gi\|37681016\|ref\|NP_935625.1\| signal peptidase I [Vibrio vulnificus YJ016], gi\|37199766\|dbj\|BAC95596....	321.0	[0..1]	[298..1]
gi\|85835839, gi\|... - gi\|86146360\|ref\|ZP_01064684.1\| Signal peptidase I [Vibrio sp. MED222], gi\|85835839\|gb\|EAQ53973.1\| Si...	320.0	[0..1]	[298..1]
gi\|149746519, gi... - gi\|153839960\|ref\|ZP_01992627.1\| signal peptidase I [Vibrio parahaemolyticus AQ3810], gi\|149746519\|gb... gi\|28899347, gi\|... - gi\|28899347\|ref\|NP_798952.1\| signal peptidase I [Vibrio parahaemolyticus RIMD 2210633], gi\|28807583\|... gi\|28807583 - gi\|28807583\|dbj\|BAC60836.1\| signal peptidase I [Vibrio parahaemolyticus RIMD 2210633]	316.0	[0..1]	[298..1]
gi\|194538393, gi... - gi\|75854071\|ref\|ZP_00761791.1\| COG0681: Signal peptidase I [Vibrio sp. Ex25], gi\|254230523\|ref\|ZP_04... gi\|91227853, gi\|... - gi\|91227853\|ref\|ZP_01262026.1\| signal peptidase I [Vibrio alginolyticus 12G01], gi\|91188363\|gb\|EAS74...	315.0	[0..1]	[298..1]
gi\|54310188, gi\|... - gi\|54310188\|ref\|YP_131208.1\| putative signal peptidase I [Photobacterium profundum SS9], gi\|46914629...	313.0	[0..1]	[298..1]
gi\|90412085, gi\|... - gi\|90412085\|ref\|ZP_01220092.1\| putative signal peptidase I [Photobacterium profundum 3TCK], gi\|90327...	310.0	[0..1]	[298..1]
gi\|89075089, gi\|... - gi\|89075089\|ref\|ZP_01161530.1\| putative signal peptidase I [Photobacterium sp. SKA34], gi\|89049176\|g...	308.0	[0..1]	[297..1]
gi\|90580324, gi\|... - gi\|90580324\|ref\|ZP_01236131.1\| putative signal peptidase I [Vibrio angustum S14], gi\|90438626\|gb\|EAS...	306.0	[0..1]	[297..1]

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Predicted Domain #1

Region A:
Residues: [1-298]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MANTFSLILV IVTLVTGIVW TLEKLVWAKK RQQKQAHLQA QTPDMPASAL DKVVAQPWWI  60
   61 ENSVSIFPVI AFVLVLRSFI YEPFQIPSGS MMPTLLVGDF ILVEKYAYGL KDPVWRTQLV 120
  121 ETGKPERGDI VVFKYPVNPE IDYIKRVVGM PGDTVRYSAG KELCIQHQGE SECQAVKLSN 180
  181 VQESEFYQNE IPLIQLNEQL GKVEHNILVN PLSIDNVANY RPRSGVNEWV VPQGHYFVMG 240
  241 DNRDNSADSR FWGFVPEQNL VGKAVAIWIS FEFERAEDSV LPRWIPTGVR FNRVGGIH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.522879
Match:	1t7dA
Description:	Crystal structure of Escherichia coli type I signal peptidase in complex with a lipopeptide inhibitor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	0.485843348899278	bayes_pls_golite062009
catalytic activity	0.415601732277814	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	0.237734983138449	bayes_pls_golite062009
hydrolase activity	0.188292586303013	bayes_pls_golite062009
protein binding	0.0579980138351139	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: