YRC Public Data Repository - Protein Structure Prediction

Protein:	FABZ_VIBCH
Organism:	Vibrio cholerae O1 biovar El Tor str. N16961
Length:	153 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FABZ_VIBCH.

Description	E-value	Query Range	Subject Range
gi\|254225762, gi... - gi\|75820858\|ref\|ZP_00750896.1\| COG0764: 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) ... FABZ_VIBCM - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae serotype O1 (strain M66-2) ... FABZ_VIBC3 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae serotype O1 (strain ATCC 39... gi\|229349072, gi... - gi\|229513891\|ref\|ZP_04403353.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229355182, gi... - gi\|229507677\|ref\|ZP_04397182.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229524251, gi... - gi\|229524251\|ref\|ZP_04413656.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229522195, gi... - gi\|229522195\|ref\|ZP_04411612.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|229332522, gi... - gi\|229528748\|ref\|ZP_04418138.1\| (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase [Vibrio cho... gi\|121549521, gi... - gi\|121586255\|ref\|ZP_01676045.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|124119779, gi... - gi\|153221250\|ref\|ZP_01952265.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|183012862, gi... - gi\|183179451\|ref\|ZP_02957662.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|153213814, gi... - gi\|153213814\|ref\|ZP_01949022.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|126512347, gi... - gi\|153817079\|ref\|ZP_01969746.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... gi\|153825348, gi... - gi\|153825348\|ref\|ZP_01978015.1\| (3R)-hydroxymyristoyl-(acyl-carrier-protein) dehydratase [Vibrio cho... tr\|B2D710\|B2D710... - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio cholerae MZO-3 GN=fabZ PE=3 SV=1, 3-...	205.0	[0..1]	[153..1]
FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum GN=fabZ PE=3 SV=1 FABZ_PHOPR - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Photobacterium profundum (strain SS9) GN=fa...	205.0	[0..4]	[153..1]
gi\|90413540, gi\|... - gi\|90413540\|ref\|ZP_01221531.1\| (3R)-hydroxymyristoyl ACP dehydratase [Photobacterium profundum 3TCK]...	205.0	[0..4]	[153..1]
gi\|91191570, gi\|... - gi\|91223484\|ref\|ZP_01258749.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio alginolyticus 12G01], g...	203.0	[0..4]	[153..1]
FABZ_VIBFM - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio fischeri (strain MJ11) GN=fabZ PE=3 ... FABZ_VIBF1 - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio fischeri (strain ATCC 700601 / ES114...	202.0	[0..4]	[153..1]
FABZ_VIBPA - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Vibrio parahaemolyticus GN=fabZ PE=3 SV=... FABZ_VIBPA - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio parahaemolyticus serotype O3:K6 (str... gi\|153839484, gi... - gi\|153839484\|ref\|ZP_01992151.1\| beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ [Vibrio par...	201.0	[0..4]	[153..1]
FABZ_VIBVU - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio vulnificus (strain CMCP6) GN=fabZ PE... FABZ_VIBVY - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio vulnificus (strain YJ016) GN=fabZ PE... FABZ_VIBVU - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase OS=Vibrio vulnificus GN=fabZ PE=3 SV=2	201.0	[0..4]	[153..1]
FABZ_PSEHT - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Pseudoalteromonas haloplanktis (strain TAC ...	200.0	[0..4]	[153..1]
FABZ_VIBTL - 3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ OS=Vibrio tasmaniensis (strain LGP32) GN=fabZ ... gi\|86146878, gi\|... - gi\|86146878\|ref\|ZP_01065197.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio sp. MED222], gi\|8583533...	200.0	[0..4]	[153..1]
gi\|84376882, gi\|... - gi\|84389781\|ref\|ZP_00991333.1\| (3R)-hydroxymyristoyl ACP dehydratase [Vibrio splendidus 12B01], gi\|8...	200.0	[0..4]	[153..1]

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Predicted Domain #1

Region A:
Residues: [1-153]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMTLTTDKKT MNITEIQSLL PHRYPFLLID RVTDYEEGKY LIGLKNVSVN EPQFTGHFPQ  60
   61 LPVFPGVLIL EAMAQATGLL AFKTFGAPKE NELYYFASID EAKFRKPVTP GDQLMVEVEF 120
  121 LKERRGIALF NGVAKVDGDV VCSAQLKCAR REF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.0
Match:	1u1zA
Description:	The Structure of (3R)-hydroxyacyl-ACP dehydratase (FabZ)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
CoA hydrolase activity	1.75530090056705	bayes_pls_golite062009
catalytic activity	1.11649534052993	bayes_pls_golite062009
thiolester hydrolase activity	0.65794221902015	bayes_pls_golite062009
3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
3-hydroxyacyl-[acyl-carrier-protein] dehydratase activity	0.57527342054578	bayes_pls_golite062009
acyl-CoA thioesterase activity	0.24094527143225	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: