YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|2143464, gi\|9...
Organism:	Mus sp.
Length:	181 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|2143464, gi|9....

Description	E-value	Query Range	Subject Range
VHL_RAT - Von Hippel-Lindau disease tumor suppressor OS=Rattus norvegicus GN=Vhl PE=1 SV=1 gi\|1245912 - gi\|1245912\|gb\|AAB35675.1\| von Hippel-Lindau tumor suppressor gene homolog [Rattus sp.]	302.0	[0..1]	[181..1]
gi\|21730827 - gi\|21730827\|pdb\|1LQB\|C Chain C, Crystal Structure Of A Hydroxylated Hif-1 Alpha Peptide Bound To The...	281.0	[0..20]	[179..3]
gi\|197102444 - gi\|197102444\|ref\|NP_001126390.1\| von Hippel-Lindau tumor suppressor [Pongo abelii] gi\|55731296 - gi\|55731296\|emb\|CAH92362.1\| hypothetical protein [Pongo abelii]	279.0	[0..6]	[179..38]
gi\|76648503 - gi\|76648503\|ref\|XP_613870.2\| PREDICTED: similar to Von Hippel-Lindau disease tumor suppressor (pVHL)...	278.0	[0..15]	[177..24]
VHL_CANLF - Von Hippel-Lindau disease tumor suppressor OS=Canis lupus familiaris GN=VHL PE=2 SV=1	278.0	[0..6]	[180..38]
gi\|30387874 - gi\|30387874\|gb\|AAP32238.1\| von Hippel-Lindau tumor suppressor gene [Rattus sp.]	217.0	[0..31]	[153..1]
gi\|163916476, gi... - gi\|62858543\|ref\|NP_001016367.1\| von Hippel-Lindau tumor suppressor [Xenopus (Silurana) tropicalis], ...	193.0	[0..27]	[168..12]
gi\|109034764 - gi\|109034764\|ref\|XP_001090152.1\| PREDICTED: similar to Von Hippel-Lindau disease tumor suppressor (p...	190.0	[0..79]	[179..29]

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Predicted Domain #1

Region A:
Residues: [1-181]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPRKAASPEE AAGEPGPEEM EAGRPRPVLR SVNSREPSQV IFCNRSPRVV LPLWLNFDGE  60
   61 PQPYPILPPG TGRRIHSYRG HLWLFRDAGT HDGLLVNQTE LFVPSLNVDG QPIFANITLP 120
  121 VYTLKERCLQ VVRSLVKPEN YRRLDIVRSL YEDLEDYPSV RKDIQRLSQE HLESQHLEEE 180
  181 P

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	76.045757
Match:	1lqbC
Description:	VHL
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits