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View Structure Prediction Details

Protein: gi|7470838
Organism: Synechocystis sp.
Length: 998 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7470838.

Description E-value Query
Range
Subject
Range
gi|117607304, gi... - gi|69262014|ref|ZP_00608635.1| PAS [Magnetococcus sp. MC-1], gi|68244815|gb|EAN26965.1| PAS [Magneto...
396.0 [0..1] [981..89]
gi|68214395, gi|... - gi|91776115|ref|YP_545871.1| periplasmic sensor hybrid histidine kinase [Methylobacillus flagellatus...
363.0 [0..20] [974..125]
gi|90022618, gi|... - gi|90022618|ref|YP_528445.1| two-component hybrid sensor and regulator [Saccharophagus degradans 2-4...
356.0 [0..20] [989..108]
gi|106881934, gi... - gi|119946606|ref|YP_944286.1| fused histidine kinase sensor/response regulator [Psychromonas ingraha...
352.0 [0..20] [988..108]
gi|89082125, gi|... - gi|89093729|ref|ZP_01166676.1| sensor histidine kinase with a response regulator receiver domain [Oc...
344.0 [0..20] [979..108]
gi|42521923, gi|... - gi|42521923|ref|NP_967303.1| sensory transduction histidine kinase [Bdellovibrio bacteriovorus HD100...
342.0 [0..497] [980..647]
gi|39997412, gi|... - gi|39997412|ref|NP_953363.1| sensory box histidine kinase/response regulator [Geobacter sulfurreduce...
342.0 [0..293] [996..163]
gi|114566853, gi... - gi|71541312|ref|ZP_00663086.1| PAS [Syntrophomonas wolfei str. Goettingen], gi|71492116|gb|EAO24426....
341.0 [0..343] [973..25]
gi|125973324, gi... - gi|67876007|ref|ZP_00505065.1| PAS [Clostridium thermocellum ATCC 27405], gi|67850331|gb|EAM45912.1|...
340.0 [0..400] [979..214]
gi|118502571, gi... - gi|71836691|ref|ZP_00676459.1| PAS [Pelobacter propionicus DSM 2379], gi|71742903|gb|EAO38053.1| PAS...
340.0 [0..159] [989..8]

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Predicted Domain #1
Region A:
Residues: [1-174]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKFLDLLQK YWLLPCLLLA GYGGNYFKLH IFFGVDFLFG SIATLLVLVC YSLPWGLVSA  60
   61 AIAGSHTLII WRHGYGILII ILEALVVGLM LRRRQTNLVL INSLFWLLIG IPLVYIFYRW 120
  121 GLNMTSVTTS LITLKQATNG IFNSLIASFL ITGFGLSKQK FSPSTNPAFF PWKK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [175-463]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LSFEQTLFNL LVAFVFFPLF FITVVNGQEA FVQMEKQTVQ ELTALSIPIQ NSVEDWYQSH  60
   61 LEGAEVFATE ILPLVAAINQ GNGAQLPALS LMTHTIQTAF TGFSNIYVGD RQGQIIASSP 120
  121 EFNEVGESRL GLIQAEKIAG FSIPSQIQVS PLHRTNVNVD PHVAITIPLV ANNSFEGFIN 180
  181 ASLNLAKMKD LLYANRVSKE LNITLINGQN QVVASTIANV LPLEIYQPFE GGDPRDLGSS 240
  241 NYHWYPDTPA NPTIRWRDSY YYHILPLDKI NDWQLVLGLP ARESIEKLQ

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.16
Match: 2p7jA
Description: No description for 2p7jA was found.

Predicted functions:

Term Confidence Notes
catalytic activity 0.0704240813903547 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [464-576]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQSVQKLGLL LFLSLVGLVV AIGVSKRVAN PLLTLAKITT DIPTKMQYQG LTPIALRSEV  60
   61 SEVITLNENF NEMLITLQNQ FKIIKQAKDN LEMRVAERTH TLIVINKQLA GEI

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 3.03
Match: 2f95B
Description: M intermediate structure of sensory rhodopsin II/transducer complex in combination with the ground state structure
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [577-843]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EERQRIEIKL REAKESAELA NRVKSEFLAN ISHEIRTPMN AILGFCDLLL QKDLSLSQTK  60
   61 KYLNAIGSSS KILLALIDDI LDISKIEAGK LVIHLEPVDL RVIIREIKQI FDYKAESKSL 120
  121 LLTIQIDETL NQAIYFDAVR LRQILFNLVG NALKFTEEGQ VFIYIGVEGI QVRSQGTYIS 180
  181 LAIEVTDTGI GIAPEDQAKI FDVFTQSQGQ STRKYGGTGL GLTITRRLTA LLGGEISLSS 240
  241 RLGEGSTFIL HFPAVRLVEN SLKSDLT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 2c2aA
Description: Structure of the entire cytoplasmic portion of a sensor histidine kinase protein
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [844-998]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NGDGGNLTDR LGSMSSSSAN TTEKLLPTRV GNMAPDNNSL GNHNGPSQGF PRAVPLIDQA  60
   61 QRQQLISLLE QEETNVWNKL RHTLISRQIR NFGDRLSSWG NEYGWEDLHT YGQSIIKALE 120
  121 NFDSRRLEQL MGQFPQYRAS LTEVSAGVDG KHASE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 19.522879
Match: 1mvoA
Description: PhoP receiver domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
signal transducer activity 2.07885074402355 bayes_pls_golite062009
molecular transducer activity 2.07885074402355 bayes_pls_golite062009
transcription regulator activity 1.72455852503325 bayes_pls_golite062009
two-component response regulator activity 1.53373140048441 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle