YRC Public Data Repository - Protein Structure Prediction

Protein:	UPP_STRPN
Organism:	Streptococcus pneumoniae TIGR4
Length:	209 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for UPP_STRPN.

Description	E-value	Query Range	Subject Range
UPP_STRSL - Uracil phosphoribosyltransferase OS=Streptococcus salivarius GN=upp PE=3 SV=1 gi\|228476631, gi... - gi\|228476631\|ref\|ZP_04061313.1\| uracil phosphoribosyltransferase [Streptococcus salivarius SK126], g...	248.0	[0..1]	[209..1]
gi\|55736433, gi\|... - gb\|AAV61958.1\| uracil phosphoribosyltransferase [Streptococcus thermophilus CNRZ1066], gb\|AAV60075.... UPP_STRT2 - Uracil phosphoribosyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) GN=... UPP_STRTD - Uracil phosphoribosyltransferase OS=Streptococcus thermophilus (strain ATCC BAA-491 / LMD-9) GN=upp ... UPP_STRT1 - Uracil phosphoribosyltransferase OS=Streptococcus thermophilus (strain CNRZ 1066) GN=upp PE=3 SV=1	247.0	[0..1]	[209..1]
gi\|89210214, gi\|... - gi\|89210214\|ref\|ZP_01188606.1\| Uracil phosphoribosyl transferase [Halothermothrix orenii H 168], gi\|...	246.0	[0..1]	[209..1]
UPP_STRMU - Uracil phosphoribosyltransferase OS=Streptococcus mutans serotype c (strain ATCC 700610 / UA159) GN=... gi\|254996869 - gi\|254996869\|dbj\|BAH87470.1\| uracil phosphoribosyltransferase [Streptococcus mutans NN2025] UPP_STRMU - Uracil phosphoribosyltransferase OS=Streptococcus mutans GN=upp PE=3 SV=1	245.0	[0..1]	[209..1]
UPP_STRA3 - Uracil phosphoribosyltransferase OS=Streptococcus agalactiae serotype III (strain NEM316) GN=upp PE=... UPP_STRA5 - Uracil phosphoribosyltransferase OS=Streptococcus agalactiae serotype V (strain ATCC BAA-611 / 2603 ... UPP_STRA1 - Uracil phosphoribosyltransferase OS=Streptococcus agalactiae serotype Ia GN=upp PE=3 SV=1 UPP_STRA5 - Uracil phosphoribosyltransferase OS=Streptococcus agalactiae serotype V GN=upp PE=3 SV=1 UPP_STRA1 - Uracil phosphoribosyltransferase OS=Streptococcus agalactiae serotype Ia (strain ATCC 27591 / A909 /... gi\|77414902, gi\|... - gi\|77414902\|ref\|ZP_00791007.1\| uracil phosphoribosyltransferase [Streptococcus agalactiae 515], gi\|7... gi\|77409460, gi\|... - gi\|77409460\|ref\|ZP_00786153.1\| uracil phosphoribosyltransferase [Streptococcus agalactiae COH1], gi\|... gi\|77174294, gi\|... - gi\|77407099\|ref\|ZP_00784099.1\| uracil phosphoribosyltransferase [Streptococcus agalactiae H36B], gi\|... UPP_STRA3 - Uracil phosphoribosyltransferase OS=Streptococcus agalactiae serotype III GN=upp PE=3 SV=1	245.0	[0..1]	[209..1]
gi\|229331222, gi... - gi\|229497796\|ref\|ZP_04391495.1\| uracil phosphoribosyltransferase [Geobacillus sp. Y412MC52], gi\|2293... gi\|1765902, gi\|2... - gi\|21465611\|pdb\|1I5E\|B Chain B, Crystal Structure Of Bacillus Caldolyticus Uracil Phosphoribosyltran... UPP_GEOKA - Uracil phosphoribosyltransferase OS=Geobacillus kaustophilus GN=upp PE=3 SV=1 gi\|220709118, gi... - gi\|221087065\|ref\|ZP_03556605.1\| uracil phosphoribosyltransferase [Geobacillus sp. Y412MC61], gi\|2207... UPP_GEOKA - Uracil phosphoribosyltransferase OS=Geobacillus kaustophilus (strain HTA426) GN=upp PE=3 SV=1	245.0	[0..1]	[209..1]
gi\|223933329, gi... - gi\|81097024\|ref\|ZP_00875340.1\| Uracil phosphoribosyl transferase [Streptococcus suis 89/1591], gi\|80...	244.0	[0..1]	[209..1]
gi\|148997180, gi... - gi\|148997180\|ref\|ZP_01824834.1\| uracil phosphoribosyltransferase [Streptococcus pneumoniae SP11-BS70... gi\|147928723, gi... - gi\|148992406\|ref\|ZP_01822101.1\| uracil phosphoribosyltransferase [Streptococcus pneumoniae SP9-BS68]... UPP_STRR6 - Uracil phosphoribosyltransferase OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R6) GN=upp PE=3 ... gi\|147930687, gi... - gi\|149020385\|ref\|ZP_01835277.1\| uracil phosphoribosyltransferase [Streptococcus pneumoniae SP23-BS72... gi\|147760778, gi... - gi\|149007623\|ref\|ZP_01831240.1\| uracil phosphoribosyltransferase [Streptococcus pneumoniae SP18-BS74... gi\|149003357, gi... - gi\|149003357\|ref\|ZP_01828246.1\| uracil phosphoribosyltransferase [Streptococcus pneumoniae SP14-BS69... gi\|168488413, gi... - gi\|183572892\|gb\|EDT93420.1\| uracil phosphoribosyltransferase [Streptococcus pneumoniae SP195], gi\|16...	244.0	[0..1]	[209..1]
UPP_PEDPA - Uracil phosphoribosyltransferase OS=Pediococcus pentosaceus (strain ATCC 25745 / 183-1w) GN=upp PE=3...	243.0	[0..1]	[209..1]

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Predicted Domain #1

Region A:
Residues: [1-209]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGKIEVINHP LIQHKLSILR RTDTSTKAFR ELVDEIAMLM GYEVLRDLPL EDVEIETPIT  60
   61 KTVQKQLAGK KLAIVPILRA GIGMVDGLLN LVPAAKVGHI GMYRDEETLQ PVEYLVKLPE 120
  121 DIDQRQIFVV DPMLATGGSA ILAVDSLKKR GASNIKFVCL VSAPEGVKAL QEAHPDVEIF 180
  181 TAALDERLNE HGYIVPGLGD AGDRLFGTK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.045757
Match:	1i5eA
Description:	Uracil PRTase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
uracil phosphoribosyltransferase activity	3.97944228585882	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.91023158228049	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	3.07502596276449	bayes_pls_golite062009
transferase activity	2.73727660668741	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	2.67945744445872	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.53679639481311	bayes_pls_golite062009
catalytic activity	2.30431811394775	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	0.947697983706416	bayes_pls_golite062009
diphosphotransferase activity	0.749909396904601	bayes_pls_golite062009
binding	0.730385736169604	bayes_pls_golite062009
nucleic acid binding	0.552133387792911	bayes_pls_golite062009
DNA binding	0.439741935655503	bayes_pls_golite062009
transcription regulator activity	0.396538943915776	bayes_pls_golite062009
amidophosphoribosyltransferase activity	0.360901350940423	bayes_pls_golite062009
purine binding	0.358545436706029	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	0.148898393751978	bayes_pls_golite062009
nucleobase binding	0.0803493215714011	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: