YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30258797, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	116 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30258797, gi|....

Description	E-value	Query Range	Subject Range
gi\|15895575, gi\|... - gi\|15895575\|ref\|NP_348924.1\| anti-anti-sigma factor (antagonist of SpoIIAB) [Clostridium acetobutyli... gi\|25299040 - pir\|\|E97184 anti-anti-sigma factor (antagonist of SpoIIAB) [imported] - Clostridium acetobutylicum	7.0E-24	[3..113]	[1..111]
SP2AA_BACME - Anti-sigma F factor antagonist OS=Bacillus megaterium GN=spoIIAA PE=3 SV=1	8.0E-24	[1..116]	[1..116]
gi\|220931544, gi... - gi\|89210648\|ref\|ZP_01189035.1\| Anti-sigma factor antagonist [Halothermothrix orenii H 168], gi\|89159...	4.0E-23	[3..113]	[1..111]
gi\|50513738, gi\|... - gi\|50513742\|pdb\|1THN\|D Chain D, Crystal Structures Of The Adp And Atp Bound Forms Of The Bacillus An... gi\|229497585, gi... - gi\|229497585\|ref\|ZP_04391285.1\| anti-sigma-factor antagonist [Geobacillus sp. Y412MC52], gi\|22933146... gi\|56420845, gi\|... - gi\|56420845\|ref\|YP_148163.1\| anti-sigma F factor antagonist (stage II sporulation protein AA) [Geoba... gi\|220708932, gi... - gi\|221087282\|ref\|ZP_03556821.1\| anti-sigma-factor antagonist [Geobacillus sp. Y412MC61], gi\|22070893...	6.0E-23	[1..116]	[1..116]
gi\|10174153, gi\|... - gi\|15614099\|ref\|NP_242402.1\| anti-sigma F factor antagonist (stage II sporulation protein AA) [Bacil... gi\|25299039 - pir\|\|H83841 anti-sigma F factor antagonist (stage II sporulation protein AA) spoIIAA [imported] - Ba...	7.0E-23	[1..116]	[1..116]
SP2AA_BACCO - Anti-sigma F factor antagonist OS=Bacillus coagulans GN=spoIIAA PE=3 SV=2 gi\|229325084, gi... - gi\|229543945\|ref\|ZP_04433004.1\| anti-sigma-factor antagonist [Bacillus coagulans 36D1], gi\|229325084...	8.0E-23	[1..116]	[1..116]
gi\|154686589, gi... - gi\|63146680\|emb\|CAG28931.1\| anti-sigma F factor antagonist [Bacillus amyloliquefaciens FZB42], gi\|15...	1.0E-22	[1..116]	[1..116]
gi\|50513749, gi\|... - gi\|50513753\|pdb\|1TIL\|F Chain F, Crystal Structures Of The Adp And Atp Bound Forms Of The Bacillus An...	1.0E-22	[1..116]	[4..119]
gi\|89086183, gi\|... - gi\|89099053\|ref\|ZP_01171932.1\| anti-sigma F factor antagonist (stage II sporulation protein AA) [Bac...	2.0E-22	[1..116]	[1..116]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLSMQLEVK RDVLCVRLAG ELDHHTAEEL RTKVTDMIET HGVHHIVLSL ENLSFMDSSG  60
   61 LGVILGRYKH VKGLGGEMVV CAISPPVKRL FEMSGLFKIV RLEESEAHAL ATLGVA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	24.522879
Match:	1th8B
Description:	Crystal Structures of the ADP and ATP bound forms of the Bacillus Anti-sigma factor SpoIIAB in complex with the Anti-anti-sigma SpoIIAA: inhibitory complex with ADP, crystal form II
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.51984028488182	bayes_pls_golite062009
protein binding	0.99113615143823	bayes_pls_golite062009
transcription regulator activity	0.893093767470901	bayes_pls_golite062009
antisigma factor binding	0.52065892308738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: