YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259288, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	344 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259288, gi|....

Description	E-value	Query Range	Subject Range
SYFA_AZOVD - Phenylalanine--tRNA ligase alpha subunit OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=ph... gi\|23104002, gi\|... - gi\|67157284\|ref\|ZP_00418586.1\| Phenylalanyl-tRNA synthetase, alpha subunit [Azotobacter vinelandii A...	0.0	[3..342]	[2..338]
gi\|19386912 - gi\|19386912\|gb\|AAL87034.1\|AF332624_5 phenylalanyl-tRNA-synthetase alpha subunit [Azotobacter vinelan...	0.0	[3..342]	[2..338]
SYFA_PSE14 - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas savastanoi pv. phaseolicola (strain 1448A / ... SYFA_PSEU2 - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas syringae pv. syringae (strain B728a) GN=pheS...	3.0E-99	[3..342]	[2..338]
SYFA_PSEE4 - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas entomophila (strain L48) GN=pheS PE=3 SV=1 gi\|95110097 - gi\|95110097\|emb\|CAK14802.1\| phenylalanyl-tRNA synthetase, alpha-subunit [Pseudomonas entomophila L48...	5.0E-99	[3..342]	[2..338]
SYFA_GEOKA - Phenylalanine--tRNA ligase alpha subunit OS=Geobacillus kaustophilus (strain HTA426) GN=pheS PE=3 SV... SYFA_GEOKA - Phenylalanyl-tRNA synthetase alpha chain OS=Geobacillus kaustophilus GN=pheS PE=3 SV=1	6.0E-99	[1..341]	[1..341]
SYFA_PSEF5 - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=...	1.0E-98	[3..342]	[2..338]
SYFA_PSESM - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=pheS ... gi\|213970491, gi... - gi\|213970491\|ref\|ZP_03398618.1\| phenylalanyl-tRNA synthetase, alpha subunit [Pseudomonas syringae pv... SYFA_PSESM - Phenylalanyl-tRNA synthetase alpha chain OS=Pseudomonas syringae pv. tomato GN=pheS PE=3 SV=1	1.0E-98	[3..342]	[2..338]
SYFA_PSEPG - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas putida (strain GB-1) GN=pheS PE=3 SV=1 tr\|E4R606\|E4R606... - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas putida (strain BIRD-1) GN=pheS PE=3 SV=1 tr\|I7BCH0\|I7BCH0... - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas putida (strain DOT-T1E) GN=pheS PE=3 SV=1 SYFA_PSEP1 - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas putida (strain F1 / ATCC 700007) GN=pheS PE=... SYFA_PSEPK - Phenylalanine--tRNA ligase alpha subunit OS=Pseudomonas putida (strain KT2440) GN=pheS PE=3 SV=1	2.0E-98	[3..342]	[2..338]
SYFA_BACCN - Phenylalanine--tRNA ligase alpha subunit OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 39...	3.0E-98	[1..344]	[1..344]
SYFA_BACSU - Phenylalanine--tRNA ligase alpha subunit OS=Bacillus subtilis (strain 168) GN=pheS PE=3 SV=2 gi\|221315130 - gi\|221315130\|ref\|ZP_03596935.1\| phenylalanyl-tRNA synthetase subunit alpha [Bacillus subtilis subsp.... gi\|221320048 - gi\|221320048\|ref\|ZP_03601342.1\| phenylalanyl-tRNA synthetase subunit alpha [Bacillus subtilis subsp.... gi\|221324330 - gi\|221324330\|ref\|ZP_03605624.1\| phenylalanyl-tRNA synthetase subunit alpha [Bacillus subtilis subsp.... SYFA_BACSU - Phenylalanine--tRNA ligase alpha chain OS=Bacillus subtilis GN=pheS PE=3 SV=2	3.0E-98	[1..344]	[1..344]

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Predicted Domain #1

Region A:
Residues: [1-344]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEARLKELKQ KALELIEEAK ELKGLNDVRV AYLGKKGPIT EVLRGMGKLS AEERPRMGAL  60
   61 VNEVREAIQT RLDDKISNLE KAVIEAKLAT ETIDVTLPGR PVETGCHHPL TAVVEQIEDV 120
  121 FIGMGYEVAE GTEVEKDYYN FEALNLPKDH PARDMQDTFY ITEETLLRTH TSSVQARTME 180
  181 NNKEKGPIKI ICPGKVYRRD DDDATHSHQF MQIEGLVIDK NIRMSDLKGT LQVFVKKMFG 240
  241 EDREIRLRPS FFPFTEPSVE MDISCMMCHG KGCGTCKGTG WIEILGAGMV HPNVLEMAGY 300
  301 DSKEYQGFAF GMGAERIAML KYGVDDIRHF YTNDVRFLQQ FKRA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.69897
Match:	1b70A
Description:	Phenyl-tRNA synthetase (PheRS) alpha subunit, PheS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phenylalanine-tRNA ligase activity	13.8919118344182	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	12.5698315343202	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	12.5698315343202	bayes_pls_golite062009
aminoacyl-tRNA ligase activity	12.5592545638101	bayes_pls_golite062009
ligase activity	6.92073480193262	bayes_pls_golite062009
glycine-tRNA ligase activity	2.61548498770105	bayes_pls_golite062009
threonine-tRNA ligase activity	2.18642354927	bayes_pls_golite062009
serine-tRNA ligase activity	2.07594942154162	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
alanine-tRNA ligase activity	1.82594054955281	bayes_pls_golite062009
lysine-tRNA ligase activity	1.72324031407565	bayes_pls_golite062009
histidine-tRNA ligase activity	1.72215103383322	bayes_pls_golite062009
asparagine-tRNA ligase activity	0.921492123574877	bayes_pls_golite062009
binding	0.311307565529325	bayes_pls_golite062009
aspartate-tRNA ligase activity	0.00572514744734753	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: