YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259536, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	157 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259536, gi|....

Description	E-value	Query Range	Subject Range
LUXS_NEIMA - S-ribosylhomocysteine lyase OS=Neisseria meningitidis serogroup A GN=luxS PE=3 SV=1 gi\|11279868 - pir\|\|G81963 conserved hypothetical protein NMA0463 [imported] - Neisseria meningitidis (strain Z2491... gi\|254670865 - gi\|254670865\|emb\|CBA07346.1\| autoinducer-2 production protein [Neisseria meningitidis alpha153] LUXS_NEIMA - S-ribosylhomocysteine lyase OS=Neisseria meningitidis serogroup A / serotype 4A (strain Z2491) GN=lu...	3.0E-70	[1..147]	[1..149]
gi\|240114772 - gi\|240114772\|ref\|ZP_04728834.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae PID18] gi\|240112025 - gi\|240112025\|ref\|ZP_04726515.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae MS11] gi\|240079817 - gi\|240079817\|ref\|ZP_04724360.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae FA19] gi\|240015681 - gi\|240015681\|ref\|ZP_04722221.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae FA6140] gi\|240124798 - gi\|240124798\|ref\|ZP_04737684.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae SK-92-679] gi\|240122610 - gi\|240122610\|ref\|ZP_04735566.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae PID332] gi\|240120306 - gi\|240120306\|ref\|ZP_04733268.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae PID24-1] gi\|240116972 - gi\|240116972\|ref\|ZP_04731034.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae PID1] LUXS_NEIG1 - S-ribosylhomocysteine lyase OS=Neisseria gonorrhoeae (strain ATCC 700825 / FA 1090) GN=luxS PE=3 SV=... gi\|254492831, gi... - gi\|254492831\|ref\|ZP_05106002.1\| S-ribosylhomocysteine lyase [Neisseria gonorrhoeae 1291], gi\|2265118... gi\|240127316 - gi\|240127316\|ref\|ZP_04739977.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae SK-93-1035] LUXS_NEIG2 - S-ribosylhomocysteine lyase OS=Neisseria gonorrhoeae (strain NCCP11945) GN=luxS PE=3 SV=1 gi\|240013235 - gi\|240013235\|ref\|ZP_04720148.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae DGI18] gi\|239998053 - gi\|239998053\|ref\|ZP_04717977.1\| S-ribosylhomocysteinase [Neisseria gonorrhoeae 35/02]	4.0E-70	[1..147]	[1..149]
LUXS_VIBPA - S-ribosylhomocysteine lyase OS=Vibrio parahaemolyticus GN=luxS PE=3 SV=1 LUXS_VIBPA - S-ribosylhomocysteine lyase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=luxS ... gi\|153838707, gi... - gi\|153838707\|ref\|ZP_01991374.1\| S-Ribosylhomocysteinase (LuxS) [Vibrio parahaemolyticus AQ3810], gi\|...	4.0E-70	[1..148]	[1..150]
LUXS_NEIMB - S-ribosylhomocysteine lyase OS=Neisseria meningitidis serogroup B GN=luxS PE=3 SV=1 gi\|11279869 - pir\|\|F81020 conserved hypothetical protein NMB1981 [imported] - Neisseria meningitidis (strain MC58 ... LUXS_NEIMB - S-ribosylhomocysteine lyase OS=Neisseria meningitidis serogroup B (strain MC58) GN=luxS PE=3 SV=1	1.0E-69	[1..147]	[1..149]
LUXS_VIBAL - S-ribosylhomocysteine lyase OS=Vibrio alginolyticus GN=luxS PE=3 SV=1	2.0E-69	[1..148]	[1..150]
LUXS_ECOL5 - S-ribosylhomocysteine lyase OS=Escherichia coli O6:K15:H31 (strain 536 / UPEC) GN=luxS PE=3 SV=1 gi\|227834865, gi... - gi\|227888225\|ref\|ZP_04006030.1\| S-ribosylhomocysteine lyase [Escherichia coli 83972], gi\|227834865\|g... LUXS_ECOL6 - S-ribosylhomocysteine lyase OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) GN=luxS P... LUXS_ECOL6 - S-ribosylhomocysteine lyase OS=Escherichia coli O6 GN=luxS PE=3 SV=3 LUXS_ECOSM - S-ribosylhomocysteine lyase OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=luxS PE=3 SV=1 gi\|190908361, gi... - gi\|75241635\|ref\|ZP_00725472.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric... LUXS_ECO81 - S-ribosylhomocysteine lyase OS=Escherichia coli O81 (strain ED1a) GN=luxS PE=3 SV=1	3.0E-69	[1..148]	[1..150]
gi\|116183744, gi... - gi\|75854253\|ref\|ZP_00761958.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Vibrio s...	3.0E-69	[1..148]	[1..150]
LUXS_VIBCB - S-ribosylhomocysteine lyase OS=Vibrio campbellii (strain ATCC BAA-1116 / BB120) GN=luxS PE=3 SV=3 LUXS_VIBHA - S-ribosylhomocysteine lyase - Vibrio harveyi	3.0E-69	[1..148]	[1..150]
LUXS_ECODH - S-ribosylhomocysteine lyase OS=Escherichia coli (strain K12 / DH10B) GN=luxS PE=3 SV=1 LUXS_ESCF3 - S-ribosylhomocysteine lyase OS=Escherichia fergusonii (strain ATCC 35469 / DSM 13698 / CDC 0568-73) ... LUXS_ECO27 - S-ribosylhomocysteine lyase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=luxS PE=3 SV=1 EG12712 - S-ribosylhomocysteine lyase / S-ribosylhomocysteine lyase, autoinducer 2 (AI-2) synthesis; functions... LUXS_ECOLU - S-ribosylhomocysteine lyase OS=Escherichia coli O17:K52:H18 (strain UMN026 / ExPEC) GN=luxS PE=3 SV=... LUXS_ECO45 - S-ribosylhomocysteine lyase OS=Escherichia coli O45:K1 (strain S88 / ExPEC) GN=luxS PE=3 SV=1 sp\|B7UHB0\|LUXS_ECO27 - S-ribosylhomocysteine lyase OS=Escherichia coli O127:H6 (strain E2348/69 / EPEC) GN=luxS PE=3 SV=1 LUXS_ECOLC - S-ribosylhomocysteine lyase OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks) GN=luxS PE=3 ... gi\|237706689, gi... - gi\|237706689\|ref\|ZP_04537170.1\| S-ribosylhomocysteine lyase [Escherichia sp. 3_2_53FAA], gi\|22689972... LUXS_ECOBW - S-ribosylhomocysteine lyase OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=luxS PE=3 SV=1 gi\|251785976, gi... - gi\|251785976\|ref\|YP_003000280.1\| hypothetical protein B21_02507 [Escherichia coli BL21], gi\|24237824... gi\|253978691, gi... - gi\|254289384\|ref\|YP_003055132.1\| S-ribosylhomocysteinase [Escherichia coli BL21(DE3)], gi\|253978691\|... gi\|226839354, gi... - gi\|254037730\|ref\|ZP_04871788.1\| quorum-sensing autoinducer 2 [Escherichia sp. 1_1_43], gi\|226839354\|... gi\|253974524, gi... - gi\|254162623\|ref\|YP_003045731.1\| S-ribosylhomocysteinase [Escherichia coli B str. REL606], gi\|253974... gi\|193071009, gi... - gi\|75234097\|ref\|ZP_00718508.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric... LUXS_SHISS - S-ribosylhomocysteine lyase OS=Shigella sonnei (strain Ss046) GN=luxS PE=3 SV=1 LUXS_ECOLI - S-ribosylhomocysteine lyase (EC 4.4.1.21) (Autoinducer-2 production protein luxS) (AI-2 synthesis pr... LUXS_ECO24 - S-ribosylhomocysteine lyase OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=luxS PE=3 SV=1 EG12712 - S-ribosylhomocysteine lyase / S-ribosylhomocysteine lyase, autoinducer 2 (AI-2) synthesis; functions... LUXS_ECOHS - S-ribosylhomocysteine lyase OS=Escherichia coli O9:H4 (strain HS) GN=luxS PE=3 SV=1 LUXS_ECOK1 - S-ribosylhomocysteine lyase OS=Escherichia coli O1:K1 / APEC GN=luxS PE=3 SV=1 gi\|124500950, gi... - gi\|124528058\|ref\|ZP_01699411.1\| quorum-sensing autoinducer 2 (AI-2), LuxS [Escherichia coli B], gi\|1... LUXS_SHIDS - S-ribosylhomocysteine lyase OS=Shigella dysenteriae serotype 1 (strain Sd197) GN=luxS PE=3 SV=1 gi\|1800072, gi\|8... - gi\|89109479\|ref\|AP_003259.1\| S-ribosylhomocysteinase [Escherichia coli str. K-12 substr. W3110], gi\|... LUXS_ECOUT - S-ribosylhomocysteine lyase OS=Escherichia coli (strain UTI89 / UPEC) GN=luxS PE=3 SV=1 gi\|194418757, gi... - gi\|83569952\|ref\|ZP_00921400.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Shigella... gi\|83585147, gi\|... - gi\|83585147\|ref\|ZP_00923798.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric...	5.0E-69	[1..148]	[1..150]
LUXS_ECOSE - S-ribosylhomocysteine lyase OS=Escherichia coli (strain SE11) GN=luxS PE=3 SV=1 LUXS_ECO8A - S-ribosylhomocysteine lyase OS=Escherichia coli O8 (strain IAI1) GN=luxS PE=3 SV=1 gi\|75255951, gi\|... - gi\|75255951\|ref\|ZP_00727675.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric... gi\|191167092, gi... - gi\|75229767\|ref\|ZP_00716297.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric... gi\|194414149, gi... - gi\|75210891\|ref\|ZP_00711015.1\| COG1854: LuxS protein involved in autoinducer AI2 synthesis [Escheric... LUXS_ECO55 - S-ribosylhomocysteine lyase OS=Escherichia coli (strain 55989 / EAEC) GN=luxS PE=3 SV=1	7.0E-69	[1..148]	[1..150]

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Predicted Domain #1

Region A:
Residues: [1-157]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPSVESFELD HTIVKAPYVR HCGVHNVGSD GIVNKFDIRF CQPNKQAMKP DVIHTLEHLL  60
   61 AFNLRKYIDR YPHFDIIDIS PMGCQTGYYL VVSGTPTVRE IIDLLELTLK DAVQITEIPA 120
  121 ANETQCGQAK LHDLEGAKRL MNFWLSQDKD ELEKVFG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	65.69897
Match:	1ie0A
Description:	Autoinducer-2 production protein LuxS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-ribosylhomocysteine lyase activity	1.74759627448878	bayes_pls_golite062009
quorum sensing signal generator activity	1.39649645139585	bayes_pls_golite062009
quorum sensing response regulator activity	1.39649645139585	bayes_pls_golite062009
catalytic activity	0.00996887145100289	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: