YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|30259865, gi\|...
Organism:	Bacillus anthracis str. Ames
Length:	309 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|30259865, gi|....

Description	E-value	Query Range	Subject Range
gi\|47569263, gi\|... - gi\|47569263\|ref\|ZP_00239948.1\| Hpr(ser) kinase/phosphatase [Bacillus cereus G9241], gi\|47554034\|gb\|E...	0.0	[1..309]	[46..354]
gi\|42740244, gi\|... - gi\|42784313\|ref\|NP_981560.1\| HPr kinase/phosphorylase [Bacillus cereus ATCC 10987], gi\|42740244\|gb\|A...	0.0	[1..309]	[44..352]
gi\|75759648, gi\|... - gi\|75759648\|ref\|ZP_00739732.1\| HPR(SER) KINASE / PHOSPHATASE [Bacillus thuringiensis serovar israel...	0.0	[1..309]	[44..352]
gi\|228930162, gi... - gi\|228930162\|ref\|ZP_04093171.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar pondicherie... gi\|228917766, gi... - gi\|228917766\|ref\|ZP_04081306.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar pulsiensis ... gi\|228948879, gi... - gi\|228948879\|ref\|ZP_04111154.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar monterrey B... gi\|228936446, gi... - gi\|228936446\|ref\|ZP_04099244.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar andalousien... gi\|228596075, gi... - gi\|229187371\|ref\|ZP_04314514.1\| HPr kinase/phosphorylase [Bacillus cereus BGSC 6E1], gi\|228596075\|gb... gi\|228658762, gi... - gi\|229124667\|ref\|ZP_04253848.1\| HPr kinase/phosphorylase [Bacillus cereus 95/8201], gi\|228658762\|gb\|... gi\|65317134 - gi\|65317134\|ref\|ZP_00390093.1\| COG1493: Serine kinase of the HPr protein, regulates carbohydrate met...	0.0	[1..309]	[26..334]
gi\|228635701, gi... - gi\|229147688\|ref\|ZP_04276031.1\| HPr kinase/phosphorylase [Bacillus cereus BDRD-ST24], gi\|228635701\|g... gi\|228629921, gi... - gi\|229153317\|ref\|ZP_04281495.1\| HPr kinase/phosphorylase [Bacillus cereus m1550], gi\|228629921\|gb\|EE... gi\|229082368, gi... - gi\|229082368\|ref\|ZP_04214831.1\| HPr kinase/phosphorylase [Bacillus cereus Rock4-2], gi\|228700800\|gb\|... gi\|229112569, gi... - gi\|229112569\|ref\|ZP_04242106.1\| HPr kinase/phosphorylase [Bacillus cereus Rock1-15], gi\|228670949\|gb... gi\|229181417, gi... - gi\|229181417\|ref\|ZP_04308745.1\| HPr kinase/phosphorylase [Bacillus cereus 172560W], gi\|228601992\|gb\|... gi\|229193403, gi... - gi\|229193403\|ref\|ZP_04320351.1\| HPr kinase/phosphorylase [Bacillus cereus ATCC 10876], gi\|228590058\|... HPRK_BACCR - HPr kinase/phosphorylase OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBRC 15305 / NC... HPRK_BACCQ - HPr kinase/phosphorylase OS=Bacillus cereus (strain Q1) GN=hprK PE=3 SV=1 gi\|206970366, gi... - gi\|206970366\|ref\|ZP_03231319.1\| HPr(Ser) kinase/phosphatase [Bacillus cereus AH1134], gi\|206734943\|g... gi\|161511017 - gi\|161511017\|ref\|NP_981560.2\| HPr kinase/phosphorylase [Bacillus cereus ATCC 10987] HPRK_BACC4 - HPr kinase/phosphorylase OS=Bacillus cereus (strain B4264) GN=hprK PE=3 SV=1 HPRK_BACC7 - HPr kinase/phosphorylase OS=Bacillus cereus (strain AH187) GN=hprK PE=3 SV=1 gi\|228798274, gi... - gi\|228961389\|ref\|ZP_04123003.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar pakistani s... gi\|229050823, gi... - gi\|229050823\|ref\|ZP_04194375.1\| HPr kinase/phosphorylase [Bacillus cereus AH676], gi\|228722479\|gb\|EE... gi\|228804192, gi... - gi\|228955400\|ref\|ZP_04117405.1\| HPr kinase/phosphorylase [Bacillus thuringiensis serovar kurstaki st...	0.0	[1..309]	[1..309]
HPRK_BACWK - HPr kinase/phosphorylase OS=Bacillus weihenstephanensis (strain KBAB4) GN=hprK PE=3 SV=1 gi\|229063809, gi... - gi\|229063809\|ref\|ZP_04200113.1\| HPr kinase/phosphorylase [Bacillus cereus AH603], gi\|228716446\|gb\|EE... gi\|228613578, gi... - gi\|229169864\|ref\|ZP_04297560.1\| HPr kinase/phosphorylase [Bacillus cereus AH621], gi\|228613578\|gb\|EE...	0.0	[1..309]	[1..309]
HPRK_BACCN - HPr kinase/phosphorylase OS=Bacillus cytotoxicus (strain DSM 22905 / CIP 110041 / 391-98 / NVH 391-9...	0.0	[1..309]	[1..309]
HPRK_BACHD - HPr kinase/phosphorylase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9... HPRK_BACHD - HPr kinase/phosphorylase OS=Bacillus halodurans GN=hprK PE=3 SV=1	0.0	[1..309]	[1..309]
HPRK_LISMO - HPr kinase/phosphorylase OS=Listeria monocytogenes GN=hprK PE=3 SV=1 gi\|47015536, gi\|... - gi\|47096075\|ref\|ZP_00233676.1\| HPr(Ser) kinase/phosphatase [Listeria monocytogenes str. 1/2a F6854],... gi\|224503276 - gi\|224503276\|ref\|ZP_03671583.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL R2-561] gi\|47018857, gi\|... - gi\|47092769\|ref\|ZP_00230554.1\| HPr(Ser) kinase/phosphatase [Listeria monocytogenes str. 4b H7858], g... gi\|224499840 - gi\|224499840\|ref\|ZP_03668189.1\| HPr kinase/phosphorylase [Listeria monocytogenes Finland 1988] HPRK_LISMF - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=hprK PE=3 SV=1 HPRK_LISMO - HPr kinase/phosphorylase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-e) GN=hpr... gi\|126942452, gi... - gi\|254900379\|ref\|ZP_05260303.1\| HPr kinase/phosphorylase [Listeria monocytogenes J0161], gi\|15318494... gi\|153197211, gi... - gi\|254831094\|ref\|ZP_05235749.1\| HPr kinase/phosphorylase [Listeria monocytogenes 10403S], gi\|1531972... gi\|254913382, gi... - gi\|254913382\|ref\|ZP_05263394.1\| HPr kinase/phosphorylase [Listeria monocytogenes J2818], gi\|15319214... gi\|153168591, gi... - gi\|254872173\|ref\|ZP_05244883.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL N1-017], gi\|153... gi\|153175735, gi... - gi\|254828058\|ref\|ZP_05232745.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL N3-165], gi\|153... gi\|254937763, gi... - gi\|254937763\|ref\|ZP_05269460.1\| HPr kinase/phosphorylase [Listeria monocytogenes F6900], gi\|15318057... HPRK_LISMH - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4a (strain HCC23) GN=hprK PE=3 SV=1 gi\|153204054, gi... - gi\|254932276\|ref\|ZP_05265635.1\| HPr kinase/phosphorylase [Listeria monocytogenes HPB2262], gi\|153204... HPRK_LISMC - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4b (strain Clip81459) GN=hprK PE=3 SV=1 gi\|254853515 - gi\|254853515\|ref\|ZP_05242863.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL R2-503] gi\|254879191 - gi\|254879191\|ref\|ZP_05251901.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J2-071] gi\|254992085 - gi\|254992085\|ref\|ZP_05274275.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J2-064] gi\|255027005 - gi\|255027005\|ref\|ZP_05298991.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J2-003] HPRK_LISMC - HPr kinase/phosphorylase OS=Listeria monocytogenes serotype 4b (strain CLIP80459) GN=hprK PE=3 SV=1 gi\|255521862 - gi\|255521862\|ref\|ZP_05389099.1\| HPr kinase/phosphorylase [Listeria monocytogenes FSL J1-175]	0.0	[2..307]	[3..308]

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Predicted Domain #1

Region A:
Residues: [1-309]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPKVRTKDLI EQFQLELISG EEGIHRPIDT SDLSRPGIEM AGFFTYYPAD RVQLLGKTEL  60
   61 TFFDTLTSDQ KQERMKALCT EETPCIIVTR NQDVPDELLQ ASRESGMPLL RSSQTTTRLS 120
  121 SRLTNYLEGK LAPTTAVHGV LVDIYGVGVL ITGQSGVGKS ETALELVKRG HRLVADDSVE 180
  181 IRQEDEDMLV GSSPDLIEHL LEIRGLGIIN VMTLFGAGAV RNYKRITLVI NLEIWDQKKN 240
  241 YDRLGLDEEK MKIIDTELTK ITLPVRPGRN LAVIIEVAAM NFRLKRMGVN AAQQFSERLM 300
  301 SAIELGNQE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	107.0
Match:	1ko7A
Description:	HPr kinase/phoshatase HprK N-terminal domain; HPr kinase HprK C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.96595957357027	bayes_pls_golite062009
phosphoenolpyruvate carboxykinase activity	0.895807668315489	bayes_pls_golite062009
carbon-carbon lyase activity	0.626079896377643	bayes_pls_golite062009
lyase activity	0.600389586904626	bayes_pls_golite062009
carboxy-lyase activity	0.593189334075365	bayes_pls_golite062009
binding	0.456582751079595	bayes_pls_golite062009
phosphoenolpyruvate carboxykinase (ATP) activity	0.0272102212862302	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: