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View Structure Prediction Details

Protein: RNH2_MANSM
Organism: Mannheimia succiniciproducens MBEL55E
Length: 198 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNH2_MANSM.

Description E-value Query
Range
Subject
Range
gi|91223487, gi|... - gi|91223487|ref|ZP_01258752.1| ribonuclease HII [Vibrio alginolyticus 12G01], gi|91191573|gb|EAS7783...
294.0 [0..3] [198..16]

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Predicted Domain #1
Region A:
Residues: [1-198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAEFEYPQGF ELIAGVDEVG RGPLVGAVVT AAVILDPNNP IDGLTDSKKL SEKKREKLAE  60
   61 EIKQKALAWA LGRAEPEEID ALNILQATML AMQRAIKNLK IQPHFVLIDG NRIPQLAIPA 120
  121 QAVVKGDSLV AEISAASIIA KVSRDHEMEV LDKQYPQYEF AKHKGYPTKV HLAKLAEFGV 180
  181 LPQHRRSFSP VRKLLENE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 59.0
Match: 2etjA
Description: Crystal structure of Ribonuclease HII (EC 3.1.26.4) (RNase HII) (tm0915) from THERMOTOGA MARITIMA at 1.74 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
ribonuclease activity 3.91517707500372 bayes_pls_golite062009
endoribonuclease activity 3.00008907756136 bayes_pls_golite062009
ribonuclease H activity 2.37346218921366 bayes_pls_golite062009
hydrolase activity 2.30893115816458 bayes_pls_golite062009
hydrolase activity, acting on ester bonds 2.26022264830742 bayes_pls_golite062009
nuclease activity 1.81796593394339 bayes_pls_golite062009
endonuclease activity 1.79009816048707 bayes_pls_golite062009
catalytic activity 1.62277843225829 bayes_pls_golite062009
exoribonuclease activity 1.48827607538468 bayes_pls_golite062009
exoribonuclease activity, producing 5'-phosphomonoesters 1.34153791988846 bayes_pls_golite062009
3'-5'-exoribonuclease activity 0.8085201347205 bayes_pls_golite062009
exonuclease activity 0.39213900591465 bayes_pls_golite062009
endoribonuclease activity, producing 5'-phosphomonoesters 0.13187450705887 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle