YRC Public Data Repository - Protein Structure Prediction

Protein:	RPPH_MANSM
Organism:	Mannheimia succiniciproducens MBEL55E
Length:	197 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPPH_MANSM.

Description	E-value	Query Range	Subject Range
gi\|229813037, gi... - gi\|229844043\|ref\|ZP_04464184.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae 6P18H1]... gi\|42631225 - gi\|42631225\|ref\|ZP_00156763.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|145641911, gi... - gi\|145641911\|ref\|ZP_01797485.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae R3021],... gi\|145641911 - gi\|145641911\|ref\|ZP_01797485.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae R3021] gi\|145636968, gi... - gi\|145636968\|ref\|ZP_01792632.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae PittHH]... gi\|145634069, gi... - gi\|145634069\|ref\|ZP_01789780.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae PittAA]... gi\|145632279, gi... - gi\|145632279\|ref\|ZP_01788014.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae 3655], ...	166.0	[0..1]	[192..1]

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Predicted Domain #1

Region A:
Residues: [1-197]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIDFDGYRPN VGIVICNRKG QVLWAKRYGQ NSWQYPQGGI NDGETPEQAM YRELYEEVGL  60
   61 TRRDVRIVYA SKQWLRYKLP KRLLRYDSKP MCIGQKQRWF LVQLMSDEKN INMNCSKSPE 120
  121 FDGWRWVSFW YPVRQVVSFK RDVYRKAMKE FACFLFDANK TVNPLSTNNN DEKKANYSAK 180
  181 KPYSPYRNQD KKRKTRV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	26.221849
Match:	1f3yA
Description:	Diadenosine tetraphosphate hydrolase (Ap4A hydrolase)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.86826130963189	bayes_pls_golite062009
catalytic activity	1.86119802438676	bayes_pls_golite062009
RNA pyrophosphohydrolase activity	0.681788425915311	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	0.544115189438	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	0.54377405132398	bayes_pls_golite062009
nucleic acid binding	0.468153646537656	bayes_pls_golite062009
binding	0.0581982566440131	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: