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View Structure Prediction Details

Protein: AL121_ARATH
Organism: Arabidopsis thaliana
Length: 556 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AL121_ARATH.

Description E-value Query
Range
Subject
Range
gi|73971844 - gi|73971844|ref|XP_538742.2| PREDICTED: similar to aldehyde dehydrogenase 1B1 precursor [Canis famil...
532.0 [0..1] [548..1]

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Predicted Domain #1
Region A:
Residues: [1-556]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYRVFASRAL RAKSLCDKSS TSLASLTLSR LNHSIPFATV DAEELSGAHP AEVQSFVQGK  60
   61 WIGSSNHNTL LDPLNGEPFI KVAEVDESGT QPFVDSLSQC PKHGLHNPFK SPERYLLYGD 120
  121 ISTKAAHMLA LPKVADFFAR LIQRVAPKSY QQAAGEVFVT RKFLENFCGD QVRFLARSFA 180
  181 IPGNHLGQQS HGYRWPYGPV TIVTPFNFPL EIPLLQLMGA LYMGNKPLLK VDSKVSIVME 240
  241 QMMRLLHYCG LPAEDVDFIN SDGKTMNKIL LEANPRMTLF TGSSRVAEKL ALDLKGRIRL 300
  301 EDAGFDWKVL GPDVQEVDYV AWQCDQDAYA CSGQKCSAQS MLFVHENWSK TPLVSKLKEL 360
  361 AERRKLEDLT IGPVLTFTTE AMLEHMENLL QIPGSKLLFG GKELKNHSIP SIYGALEPTA 420
  421 VYVPIEEILK DNKTYELVTK EIFGPFQIVT EYKKDQLPLV LEALERMHAH LTAAVVSNDP 480
  481 IFLQEVIGNS VNGTTYAGLR GRTTGAPQNH WFGPAGDPRG AGIGTPEAIK LVWSCHREVI 540
  541 YDYGPVPQGW ELPPST

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 146.0
Match: 1bxsA
Description: Aldehyde reductase (dehydrogenase), ALDH
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
oxidoreductase activity, acting on the aldehyde or oxo group of donors 5.09598561374689 bayes_pls_golite062009
oxidoreductase activity 4.47226217021998 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase [NAD(P)+] activity 3.64672165191647 bayes_pls_golite062009
1-pyrroline-5-carboxylate dehydrogenase activity 3.49281413016612 bayes_pls_golite062009
3-chloroallyl aldehyde dehydrogenase activity 3.37049090049734 bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor 3.2867555127991 bayes_pls_golite062009
aldehyde dehydrogenase (NAD) activity 2.81851373615334 bayes_pls_golite062009
catalytic activity 2.80804701752928 bayes_pls_golite062009
succinate-semialdehyde dehydrogenase activity 2.71501590413507 bayes_pls_golite062009
aldehyde dehydrogenase [NAD(P)+] activity 2.43250909158896 bayes_pls_golite062009
methylmalonate-semialdehyde dehydrogenase (acylating) activity 1.59279206536309 bayes_pls_golite062009
retinal dehydrogenase activity 1.42867174920845 bayes_pls_golite062009
glutamate-5-semialdehyde dehydrogenase activity 0.882678635212924 bayes_pls_golite062009
binding 0.438921852751754 bayes_pls_golite062009
benzaldehyde dehydrogenase activity 0.38785102096584 bayes_pls_golite062009
histidinol dehydrogenase activity 0.258030369394064 bayes_pls_golite062009
benzaldehyde dehydrogenase (NAD+) activity 0.23487570676521 bayes_pls_golite062009

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