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View Structure Prediction Details

Protein: htp-2
Organism: Caenorhabditis elegans
Length: 352 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for htp-2.

Description E-value Query
Range
Subject
Range
htp-1 - status:Partially_confirmed UniProt:Q20305 protein_id:AAK29805.2
336.0 [0..1] [352..1]

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Predicted Domain #1
Region A:
Residues: [1-254]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAPLENNYNE SLNKSKDAID DKTWSKLFPS IVSDPDRSSN FMIRAIYVVF SAVLRQRNIL  60
   61 EKEYFSKNYI TENLSCMTLS FKNLRAHQIA QLLRAAGDAT KDGFLKEISL VVTEHDGDVE 120
  121 AIEVFSMKFI YFENGGVVAR LSTDNNDQED PHFAELAQLR YEGAESVRDQ MVTIVRSVQF 180
  181 LCTKVLEPLP AEFTANFRLK YTNDAPSNFR IDGFDDSSTF YTLPDGIQSV TIGHLRPGHH 240
  241 AAHMQCWSKS MSDS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 48.09691
Match: 1s2hA
Description: The Mad2 spindle checkpoint protein possesses two distinct natively folded states
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.656741006489351 bayes_pls_golite062009
protein binding 0.160528696920916 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [255-352]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YAAELTLKGH LDKVSDMYAF NPVNVLYKSF NSEDTDPGLS QDTTESANDQ GGNVTSPVDN  60
   61 ITDSLEKTQM SPIKMRPTTR RGADDSKTRS SPYSRSRK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


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Created and Maintained by: Michael Riffle