YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7435078
Organism:	Thermotoga maritima
Length:	254 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7435078.

Description	E-value	Query Range	Subject Range
gi\|134051133, gi... - gi\|88945747\|ref\|ZP_01148913.1\| Protein of unknown function UPF0025 [Desulfotomaculum reducens MI-1],...	178.0	[0..1]	[239..1]
PP11_ACEPE - Serine/threonine-protein phosphatase PP1 isozyme 1 OS=Acetabularia peniculus PE=3 SV=1	163.0	[0..3]	[201..56]
gi\|7435129, gi\|3... - pir\|\|T09544 phosphoprotein phosphatase (EC 3.1.3.16), catalytic beta chain - alfalfa, gi\|3176072\|emb...	162.0	[0..3]	[201..55]
gi\|109105418 - gi\|109105418\|ref\|XP_001117941.1\| PREDICTED: similar to protein phosphatase 1, catalytic subunit, alp...	161.0	[0..3]	[201..156]
gi\|91084329 - gi\|91084329\|ref\|XP_972528.1\| PREDICTED: similar to Serine/threonine-protein phosphatase alpha-1 isof...	161.0	[0..3]	[201..8544]
gi\|114638772 - gi\|114638772\|ref\|XP_001151893.1\| PREDICTED: hypothetical protein [Pan troglodytes]	161.0	[0..3]	[201..55]
PP13_ARATH - Serine/threonine-protein phosphatase PP1 isozyme 3 OS=Arabidopsis thaliana GN=TOPP3 PE=2 SV=1	161.0	[0..3]	[201..56]
gi\|1535 - gi\|1535\|emb\|CAA30645.1\| unnamed protein product [Oryctolagus cuniculus]	160.0	[0..3]	[201..59]

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Predicted Domain #1

Region A:
Residues: [1-254]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRLAFFGDVH GNFEALKAVL EDMENKGVDE VFCLGDLVGY GPDPEAVVQT IMEKNIKTIM  60
   61 GNYDDAVGYS KESCGCSYAP GRETEVGDIS LKWSIENTSE KTREFLRNLP KKLSFEVEGV 120
  121 RFLLVHGSPL NELLEYVKPN TPPDRLKKIV ESVEENVVVN GHTHLPMVKW VMGKLVLNPG 180
  181 SAGRPKDGDP RASYMIVDVE NGTVSFEIVR VRYDVKTTVE KIARNGLPVE LATVLALGQT 240
  241 FDMGPGKVTF TLGR

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	23.09691
Match:	1nnwA
Description:	Hypothetical protein PF1291
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphoprotein phosphatase activity	6.45938850813828	bayes_pls_golite062009
phosphatase activity	6.05839828647676	bayes_pls_golite062009
phosphoric ester hydrolase activity	6.05508122107559	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	5.46891274080274	bayes_pls_golite062009
protein serine/threonine phosphatase activity	4.55926485636214	bayes_pls_golite062009
hydrolase activity	4.19812575932308	bayes_pls_golite062009
catalytic activity	1.76896578956606	bayes_pls_golite062009
calcium-dependent protein serine/threonine phosphatase activity	0.0863772620665402	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: