YRC Public Data Repository - Protein Structure Prediction

Protein:	DEOC_THEMA
Organism:	Thermotoga maritima MSB8
Length:	248 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DEOC_THEMA.

Description	E-value	Query Range	Subject Range
gi\|27574193, gi\|... - gi\|27574193\|pdb\|1O0Y\|B Chain B, Crystal Structure Of Deoxyribose-Phosphate Aldolase (Tm1559) From Th...	280.0	[0..1]	[248..13]
DEOC_PYRKO - Probable deoxyribose-phosphate aldolase OS=Pyrococcus kodakaraensis GN=deoC PE=3 SV=1 DEOC_THEKO - Deoxyribose-phosphate aldolase OS=Thermococcus kodakarensis (strain ATCC BAA-918 / JCM 12380 / KOD1)...	256.0	[0..29]	[241..4]
DEOC_CARHZ - Deoxyribose-phosphate aldolase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 ...	255.0	[0..30]	[242..6]
gi\|56421034, gi\|... - gi\|56421034\|ref\|YP_148352.1\| deoxyribose-phosphate aldolase [Geobacillus kaustophilus HTA426], gi\|56...	254.0	[0..31]	[246..55]
DEOC_THETN - Deoxyribose-phosphate aldolase OS=Thermoanaerobacter tengcongensis GN=deoC PE=3 SV=1 DEOC_CALS4 - Deoxyribose-phosphate aldolase OS=Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 152...	249.0	[0..24]	[248..4]
DEOC_MYCCT - Deoxyribose-phosphate aldolase OS=Mycoplasma capricolum subsp. capricolum (strain California kid / A...	246.0	[0..30]	[240..4]
gi\|80977211, gi\|... - gi\|81096736\|ref\|ZP_00875069.1\| Deoxyribose-phosphate aldolase [Streptococcus suis 89/1591], gi\|80977...	245.0	[0..30]	[241..2]
DEOC_STAHJ - Deoxyribose-phosphate aldolase OS=Staphylococcus haemolyticus (strain JCSC1435) GN=deoC PE=3 SV=1	244.0	[0..32]	[243..4]
DEOC_STAS1 - Deoxyribose-phosphate aldolase OS=Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 153...	244.0	[0..32]	[243..4]
gi\|42631419 - gi\|42631419\|ref\|ZP_00156957.1\| COG0274: Deoxyribose-phosphate aldolase [Haemophilus influenzae R2866...	243.0	[0..30]	[241..5]

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Predicted Domain #1

Region A:
Residues: [1-248]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIEYRIEEAV AKYREFYEFK PVRESAGIED VKSAIEHTNL KPFATPDDIK KLCLEARENR  60
   61 FHGVCVNPCY VKLAREELEG TDVKVVTVVG FPLGANETRT KAHEAIFAVE SGADEIDMVI 120
  121 NVGMLKAKEW EYVYEDIRSV VESVKGKVVK VIIETCYLDT EEKIAACVIS KLAGAHFVKT 180
  181 STGFGTGGAT AEDVHLMKWI VGDEMGVKAS GGIRTFEDAV KMIMYGADRI GTSSGVKIVQ 240
  241 GGEERYGG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.69897
Match:	1o0yA
Description:	Deoxyribose-phosphate aldolase DeoC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	3.04075198078553	bayes_pls_golite062009
deoxyribose-phosphate aldolase activity	2.53712494800381	bayes_pls_golite062009
transaldolase activity	0.657551083859431	bayes_pls_golite062009
lyase activity	0.437176828950096	bayes_pls_golite062009
aldehyde-lyase activity	0.41660515357045	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	0.270307871677629	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: