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View Structure Prediction Details

Protein: gi|7445034
Organism: Thermotoga maritima
Length: 179 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7445034.

Description E-value Query
Range
Subject
Range
gi|251810916, gi... - gi|251810916|ref|ZP_04825389.1| ADP-ribose diphosphatase [Staphylococcus epidermidis BCM-HMP0060], g...
gi|57866974, gi|... - gi|57866974|ref|YP_188639.1| MutT/nudix family protein [Staphylococcus epidermidis RP62A], gi|576376...
gi|27468101, gi|... - gi|27468101|ref|NP_764738.1| ADP-ribose pyrophosphatase [Staphylococcus epidermidis ATCC 12228], gi|...
152.0 [0..1] [175..1]
gi|82498927, gi|... - gi|82498927|ref|ZP_00884381.1| ADP-ribose pyrophosphatase, putative [Caldicellulosiruptor saccharoly...
148.0 [0..1] [173..1]
gi|167040190, gi... - gi|167040190|ref|YP_001663175.1| NUDIX hydrolase [Thermoanaerobacter sp. X514], gi|166854430|gb|ABY9...
gi|241902783, gi... - gi|241902783|ref|ZP_04787514.1| NUDIX hydrolase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi...
gi|242258345, gi... - gi|242258345|ref|ZP_04803159.1| NUDIX hydrolase [Thermoanaerobacter sp. X513], gi|242230130|gb|EES32...
gi|76796749, gi|... - gi|76796749|ref|ZP_00779103.1| NUDIX hydrolase [Thermoanaerobacter ethanolicus ATCC 33223], gi|76587...
147.0 [0..1] [171..1]
gi|196251996, gi... - gi|196251996|ref|ZP_03150660.1| NUDIX hydrolase [Clostridium thermocellum DSM 4150], gi|196198585|gb...
gi|48858520, gi|... - gi|67916121|ref|ZP_00509842.1| NUDIX hydrolase [Clostridium thermocellum ATCC 27405], gi|67849923|gb...
147.0 [0..1] [179..1]
gi|88944793, gi|... - gi|88944793|ref|ZP_01148017.1| NTP pyrophosphohydrolases including oxidative damage repair enzymes [...
145.0 [0..5] [169..6]
gi|20807759, gi|... - gi|20807759|ref|NP_622930.1| NTP pyrophosphohydrolase including oxidative damage repair enzyme [Ther...
gi|20807759 - gi|20807759|ref|NP_622930.1| NTP pyrophosphohydrolase including oxidative damage repair enzyme [Ther...
145.0 [0..1] [171..1]
gi|70726418, gi|... - gi|70726418|ref|YP_253332.1| ADP-ribose pyrophosphatase [Staphylococcus haemolyticus JCSC1435], gi|6...
144.0 [0..1] [175..1]
gi|73662562, gi|... - gi|73662562|ref|YP_301343.1| putative ADP-ribose pyrophosphatase [Staphylococcus saprophyticus subsp...
141.0 [0..1] [175..1]
gi|89210665, gi|... - gi|89210665|ref|ZP_01189052.1| NUDIX hydrolase [Halothermothrix orenii H 168], gi|89159763|gb|EAR794...
140.0 [0..1] [173..1]
gi|49241878, gi|... - gi|49483749|ref|YP_040973.1| putative ADP-ribose pyrophosphatase [Staphylococcus aureus subsp. aureu...
gi|227557695, gi... - gi|227557695|ref|ZP_03987742.1| ADP-ribose pyrophosphatase [Staphylococcus aureus subsp. aureus MN8]...
gi|227899991, gi... - gi|227899991|ref|ZP_04017796.1| ADP-ribose pyrophosphatase [Staphylococcus aureus subsp. aureus TCH6...
140.0 [0..1] [175..1]

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Predicted Domain #1
Region A:
Residues: [1-179]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKFYEEKIDS KRVFEGKMIS VRVDRVRLPD GRESTREVVD HPGAVVIVPV LGGKILFVEQ  60
   61 YRYPIEQVLL ELPAGKLDPG ESPEECAKRE LEEETGYRAK KLSYLGKIFT TPGFTTEVIH 120
  121 IFAAEDLEKT SQNTDPDEFI EVKEVPIEEA LSLLKNAEIE DSKTICALTR FFFAKGVIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.154902
Match: 1mk1A
Description: Structure of the MT-ADPRase in complex with ADPR, a Nudix enzyme
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.49075808737475 bayes_pls_golite062009
hydrolase activity 0.914814648797509 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 0.60834739024706 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 0.608343780811364 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle