YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7434229
Organism:	Thermotoga maritima
Length:	299 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7434229.

Description	E-value	Query Range	Subject Range
gi\|55670460, gi\|... - gi\|55670461\|pdb\|1VM7\|B Chain B, Crystal Structure Of Ribokinase (Tm0960) From Thermotoga Maritima At...	273.0	[0..1]	[299..13]
gi\|28203058, gi\|... - gi\|28210620\|ref\|NP_781564.1\| ribokinase [Clostridium tetani E88], gi\|28203058\|gb\|AAO35501.1\| ribokin...	260.0	[0..1]	[298..1]
gi\|20515184, gi\|... - gi\|20806728\|ref\|NP_621899.1\| ribokinase family sugar kinase [Thermoanaerobacter tengcongensis MB4], ... gi\|20806728 - gi\|20806728\|ref\|NP_621899.1\| Sugar kinase, ribokinase family [Thermoanaerobacter tengcongensis MB4] gi\|254478103, gi... - gi\|254478103\|ref\|ZP_05091486.1\| ribokinase [Carboxydibrachium pacificum DSM 12653], gi\|223490092\|ref...	253.0	[0..2]	[298..1]
gi\|106882307, gi... - gi\|119944129\|ref\|YP_941809.1\| ribokinase [Psychromonas ingrahamii 37], gi\|119862733\|gb\|ABM02210.1\| r...	252.0	[0..2]	[299..1]
gi\|28809384, gi\|... - gi\|28900938\|ref\|NP_800593.1\| ribokinase [Vibrio parahaemolyticus RIMD 2210633], gi\|28809384\|dbj\|BAC6... gi\|28809384 - gi\|28809384\|dbj\|BAC62426.1\| ribokinase [Vibrio parahaemolyticus RIMD 2210633] gi\|149750024, gi... - gi\|153836675\|ref\|ZP_01989342.1\| ribokinase [Vibrio parahaemolyticus AQ3810], gi\|149750024\|gb\|EDM6076...	246.0	[0..2]	[298..1]
gi\|91224727, gi\|... - gi\|91224727\|ref\|ZP_01259987.1\| ribokinase [Vibrio alginolyticus 12G01], gi\|91190273\|gb\|EAS76542.1\| r...	246.0	[0..2]	[298..1]
gi\|242258203, gi... - gi\|242258203\|ref\|ZP_04803029.1\| ribokinase [Thermoanaerobacter sp. X513], gi\|242230274\|gb\|EES32659.1... gi\|241904638, gi... - gi\|241904638\|ref\|ZP_04789317.1\| ribokinase [Thermoanaerobacter brockii subsp. finnii Ako-1], gi\|2418... gi\|167038425, gi... - gi\|76797420\|ref\|ZP_00779739.1\| Ribokinase, bacterial [Thermoanaerobacter ethanolicus ATCC 33223], gi... gi\|167038832, gi... - gi\|167038832\|ref\|YP_001661817.1\| ribokinase [Thermoanaerobacter sp. X514], gi\|166853072\|gb\|ABY91481....	246.0	[0..2]	[298..1]
gi\|52424338, gi\|... - gi\|52424338\|ref\|YP_087475.1\| RbsK protein [Mannheimia succiniciproducens MBEL55E], gi\|52306390\|gb\|AA...	245.0	[0..2]	[298..5]
gi\|37200773, gi\|... - gi\|37676232\|ref\|NP_936628.1\| sugar kinase [Vibrio vulnificus YJ016], gi\|37200773\|dbj\|BAC96598.1\| sug...	243.0	[0..2]	[297..13]
gi\|254227589, gi... - gi\|75855471\|ref\|ZP_00763121.1\| COG0524: Sugar kinases, ribokinase family [Vibrio sp. Ex25], gi\|25422...	243.0	[0..2]	[297..1]

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Predicted Domain #1

Region A:
Residues: [1-299]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLVISVVGS SNIDIVLKVD HFTKPGETQK AIEMNVFPGG KGANQAVTVA KIGEKGCRFV  60
   61 TCIGNDDYSD LLIENYEKLG ITGYIRVSLP TGRAFIEVDK TGQNRIIIFP GANAELKKEL 120
  121 IDWNTLSESD ILLLQNEIPF ETTLECAKRF NGIVIFDPAP AQGINEEIFQ YLDYLTPNEK 180
  181 EIEALSKDFF GEFLTVEKAA EKFLELGVKN VIVKLGDKGV LLVNKNEKKH FPTFKVKAVD 240
  241 TTAAGDVFNG AFAVALSEGK NPEEAVIFGT AAAAISVTRL GAQSSIPARE EVEAFLKNL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	73.39794
Match:	1vm7A
Description:	Crystal structure of Ribokinase (TM0960) from Thermotoga maritima at 2.15 A resolution
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ribokinase activity	4.13972810632318	bayes_pls_golite062009
carbohydrate kinase activity	3.53872211951287	bayes_pls_golite062009
kinase activity	2.44230326483029	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	2.43969902311075	bayes_pls_golite062009
transferase activity	2.15883296431019	bayes_pls_golite062009
phosphofructokinase activity	2.05034657907701	bayes_pls_golite062009
catalytic activity	1.74474587246986	bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor	1.01768986812996	bayes_pls_golite062009
binding	0.750579388499649	bayes_pls_golite062009
nucleic acid binding	0.43271347210671	bayes_pls_golite062009
DNA binding	0.0886731070705062	bayes_pls_golite062009
transcription regulator activity	0.0561488099067549	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: