YRC Public Data Repository - Protein Structure Prediction

Protein:	LIPB_HAEDU
Organism:	Haemophilus ducreyi 35000HP
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LIPB_HAEDU.

Description	E-value	Query Range	Subject Range
LIPB_ACTP7 - Octanoyltransferase OS=Actinobacillus pleuropneumoniae serotype 7 (strain AP76) GN=lipB PE=3 SV=1 gi\|53729241 - gi\|53729241\|ref\|ZP_00348354.1\| COG0321: Lipoate-protein ligase B [Actinobacillus pleuropneumoniae se... LIPB_ACTP2 - Octanoyltransferase OS=Actinobacillus pleuropneumoniae serotype 5b (strain L20) GN=lipB PE=3 SV=1	320.0	[0..1]	[218..1]
LIPB_HAES1 - Octanoyltransferase OS=Haemophilus somnus (strain 129Pt) GN=lipB PE=3 SV=1	316.0	[0..3]	[215..5]
LIPB_ACTSZ - Octanoyltransferase OS=Actinobacillus succinogenes (strain ATCC 55618 / 130Z) GN=lipB PE=3 SV=1	315.0	[0..1]	[215..1]
gi\|46133661 - gi\|46133661\|ref\|ZP_00157534.2\| COG0321: Lipoate-protein ligase B [Haemophilus influenzae R2866] gi\|145271241, gi... - gi\|145639684\|ref\|ZP_01795287.1\| lipoyltransferase [Haemophilus influenzae PittII], gi\|145271241\|gb\|E...	314.0	[0..2]	[211..3]
gi\|229810030, gi... - gi\|229846946\|ref\|ZP_04467052.1\| lipoyltransferase [Haemophilus influenzae 7P49H1], gi\|229810030\|gb\|E... gi\|144983807 - gi\|144983807\|gb\|EDJ91257.1\| lipoyltransferase [Haemophilus influenzae R3021] LIPB_HAEIE - Octanoyltransferase OS=Haemophilus influenzae (strain PittEE) GN=lipB PE=3 SV=1 gi\|145636769, gi... - gi\|145636769\|ref\|ZP_01792435.1\| lipoyltransferase [Haemophilus influenzae PittHH], gi\|145270067\|gb\|E... gi\|145630681 - gi\|145630681\|ref\|ZP_01786460.1\| lipoyltransferase [Haemophilus influenzae 22.4-21] gi\|144978619, gi... - gi\|145629116\|ref\|ZP_01784915.1\| lipoyltransferase [Haemophilus influenzae 22.1-21], gi\|144978619\|gb\|... LIPB_HAEI8 - Octanoyltransferase OS=Haemophilus influenzae (strain 86-028NP) GN=lipB PE=3 SV=1 gi\|53732584 - gi\|53732584\|ref\|ZP_00154758.2\| COG0321: Lipoate-protein ligase B [Haemophilus influenzae R2846]	313.0	[0..2]	[211..3]
LIPB_HISS2 - Octanoyltransferase OS=Histophilus somni (strain 2336) GN=lipB PE=3 SV=1	313.0	[0..3]	[215..5]
LIPB_VIBVY - Octanoyltransferase OS=Vibrio vulnificus (strain YJ016) GN=lipB PE=3 SV=1	313.0	[0..2]	[222..3]
LIPB_VIBVU - Octanoyltransferase OS=Vibrio vulnificus GN=lipB PE=3 SV=1 LIPB_VIBVU - Octanoyltransferase OS=Vibrio vulnificus (strain CMCP6) GN=lipB PE=3 SV=1	312.0	[0..2]	[222..3]
LIPB_PASMU - Octanoyltransferase OS=Pasteurella multocida GN=lipB PE=3 SV=1 LIPB_PASMU - Octanoyltransferase OS=Pasteurella multocida (strain Pm70) GN=lipB PE=3 SV=1	311.0	[0..1]	[215..4]
LIPB_VIBPA - Octanoyltransferase OS=Vibrio parahaemolyticus GN=lipB PE=3 SV=1 LIPB_VIBPA - Octanoyltransferase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=lipB PE=3 SV=...	310.0	[0..2]	[222..3]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHLIIRQLG IQPYERIWHQ MQDFTDQRDE HSADEIWLVQ HPAVFTQGSA GKSEHLLTSS  60
   61 HIPVVQTDRG GQITYHGEGQ QIMYVLIDIK RLKAQGKDIS VRELVTALEQ CVVRTLEDYG 120
  121 IDGYPKPDAP GVYIEGKKIC SLGLRIRKGC SFHGLAFNVN MDLTPFSHIN PCGYAGLEMT 180
  181 QLKDYISEDN AQCKLVASKL VAHFCNILGY NSQKITNKSE IQAV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	63.0
Match:	1w66A
Description:	Title withheld
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
aminoacyl-tRNA ligase activity	4.025601351766	bayes_pls_golite062009
ligase activity, forming carbon-oxygen bonds	4.02412423650651	bayes_pls_golite062009
ligase activity, forming aminoacyl-tRNA and related compounds	4.02412423650651	bayes_pls_golite062009
ligase activity	3.51191116674556	bayes_pls_golite062009
catalytic activity	1.99372273395202	bayes_pls_golite062009
phenylalanine-tRNA ligase activity	0.91205340076545	bayes_pls_golite062009
binding	0.521863822270226	bayes_pls_golite062009
serine-tRNA ligase activity	0.410923263101581	bayes_pls_golite062009
glycine-tRNA ligase activity	0.25613083187245	bayes_pls_golite062009
ATP binding	0.18403217430648	bayes_pls_golite062009
adenyl ribonucleotide binding	0.145955341735342	bayes_pls_golite062009
threonine-tRNA ligase activity	0.133891091298639	bayes_pls_golite062009
adenyl nucleotide binding	0.127823774098159	bayes_pls_golite062009
protein binding	0.0101455326199739	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: