YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|33151875, gi\|...
Organism:	Haemophilus ducreyi 35000HP
Length:	244 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|33151875, gi|....

Description	E-value	Query Range	Subject Range
gi\|38488593 - gi\|38488593\|dbj\|BAD02311.1\| peroxiredoxin like protein [Actinobacillus actinomycetemcomitans]	188.0	[0..3]	[244..12]
gi\|32034501 - gi\|32034501\|ref\|ZP_00134673.1\| COG0678: Peroxiredoxin [Actinobacillus pleuropneumoniae serovar 1 str...	188.0	[0..1]	[244..1]
gi\|255744397\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholera CIRS 101] gi\|75827887 - gi\|75827887\|ref\|ZP_00757322.1\| COG0678: Peroxiredoxin [Vibrio cholerae O395] tr\|A0A085R3Z6\|A0... - Hybrid peroxiredoxin hyPrx5 OS=Vibrio cholerae GN=DN30_1754 PE=4 SV=1 gi\|75830057, gi\|... - gi\|75830057\|ref\|ZP_00759342.1\| COG0678: Peroxiredoxin [Vibrio cholerae MO10], gi\|116190632\|ref\|ZP_01... gi\|116219574, gi... - gi\|75818991\|ref\|ZP_00749098.1\| COG0678: Peroxiredoxin [Vibrio cholerae V51], gi\|116219574\|ref\|ZP_014... gi\|262158493\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholerae INDRE 91/1] gi\|75822900, gi\|... - gi\|75822900\|ref\|ZP_00752452.1\| COG0678: Peroxiredoxin [Vibrio cholerae RC385], gi\|116216129\|ref\|ZP_0... gi\|75816566 - gi\|75816566\|ref\|ZP_00747032.1\| COG0678: Peroxiredoxin [Vibrio cholerae V52] gi\|262170114\|ref... - peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC27]	186.0	[0..4]	[244..3]
gi\|145642264, gi... - gi\|145642264\|ref\|ZP_01797829.1\| DNA-binding transcriptional regulator OxyR [Haemophilus influenzae R... gi\|145638519, gi... - gi\|145638519\|ref\|ZP_01794128.1\| hypothetical protein CGSHiII_07391 [Haemophilus influenzae PittII], ... gi\|145642264, gi... - gi\|145642264\|ref\|ZP_01797829.1\| DNA-binding transcriptional regulator OxyR [Haemophilus influenzae R... gi\|144979425, gi... - gi\|145628955\|ref\|ZP_01784755.1\| DNA-binding transcriptional regulator OxyR [Haemophilus influenzae 2... gi\|42630851 - gi\|42630851\|ref\|ZP_00156390.1\| COG0678: Peroxiredoxin [Haemophilus influenzae R2866] gi\|68057371, gi\|... - gi\|68249172\|ref\|YP_248284.1\| peroxiredoxin/glutaredoxin [Haemophilus influenzae 86-028NP], gi\|680573...	186.0	[0..3]	[243..1]
PRX5_HAEIN, Y572... - (P44758) Protein HI0572, Hybrid peroxiredoxin hyPrx5 OS=Haemophilus influenzae GN=HI_0572 PE=1 SV=1 gi\|260581018\|ref... - peroxiredoxin hybrid Prx5 [Haemophilus influenzae RdAW] PRX5_HAEIN - Hybrid peroxiredoxin hyPrx5 OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) GN...	186.0	[0..3]	[243..1]
gi\|153213977, gi... - gi\|153213977\|ref\|ZP_01949170.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae 1587], gi... gi\|121630083, gi... - gi\|121727592\|ref\|ZP_01680700.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae V52], gi\|... gi\|254846881, gi... - gi\|254851176\|ref\|ZP_05240526.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MO10], gi... gi\|229345953, gi... - gi\|229516890\|ref\|ZP_04406336.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC9], gi\|... gi\|153224207, gi... - gi\|153224207\|ref\|ZP_01954293.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MAK 757],... gi\|229369472, gi... - gi\|229606817\|ref\|YP_002877465.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MJ-1236]... gi\|126510002, gi... - gi\|153819461\|ref\|ZP_01972128.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae NCTC 8457... gi\|194537404, gi... - gi\|254225383\|ref\|ZP_04918994.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae V51], gi\|... gi\|229509765, gi... - gi\|229509765\|ref\|ZP_04399246.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae B33], gi\|... gi\|254285832, gi... - gi\|254285832\|ref\|ZP_04960794.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae AM-19226]... gi\|194536460, gi... - gi\|254222313\|ref\|ZP_04916185.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae RC385], g... gi\|153825079, gi... - gi\|153825079\|ref\|ZP_01977746.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae MZO-2], g... gi\|227119075, gi... - gi\|227119075\|ref\|YP_002820971.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae O395], g... gi\|227082753, gi... - gi\|227082753\|ref\|YP_002811304.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae M66-2], ... gi\|9657228, gi\|1... - gi\|9657228\|gb\|AAF95778.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae O1 biovar El To... gi\|229507311, gi... - gi\|229507311\|ref\|ZP_04396816.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae BX 330286... gi\|11355792 - pir\|\|D82051 peroxiredoxin family protein/glutaredoxin VC2637 [imported] - Vibrio cholerae (strain N1... gi\|121587911, gi... - gi\|121587911\|ref\|ZP_01677666.1\| peroxiredoxin family protein/glutaredoxin [Vibrio cholerae 2740-80],...	186.0	[0..4]	[244..7]
gi\|145268872, gi... - gi\|145637932\|ref\|ZP_01793574.1\| DNA-binding transcriptional regulator OxyR [Haemophilus influenzae P... gi\|144985841, gi... - gi\|145633472\|ref\|ZP_01789201.1\| hypothetical protein CGSHi3655_05114 [Haemophilus influenzae 3655], ... gi\|42630019 - gi\|42630019\|ref\|ZP_00155564.1\| COG0678: Peroxiredoxin [Haemophilus influenzae R2846]	186.0	[0..3]	[243..1]
gi\|11353834 - pir\|\|G81140 peroxiredoxin 2 family protein/glutaredoxin NMB0946 [imported] - Neisseria meningitidis ... gi\|121052038, gi... - gi\|7379834\|emb\|CAB84403.1\| putative redoxin [Neisseria meningitidis Z2491], gi\|218768030\|ref\|YP_0023... gi\|15676839, gi\|... - gi\|7226184\|gb\|AAF41352.1\| peroxiredoxin 2 family protein/glutaredoxin [Neisseria meningitidis MC58],... gi\|254671332 - gi\|254671332\|emb\|CBA08742.1\| putative peroxiredoxin/glutaredoxin family protein [Neisseria meningiti...	185.0	[0..1]	[244..1]
gi\|91188685, gi\|... - gi\|91227291\|ref\|ZP_01261716.1\| peroxiredoxin family protein/glutaredoxin [Vibrio alginolyticus 12G01...	184.0	[0..6]	[241..5]
gi\|46156414, gi\|... - gi\|46156414\|ref\|ZP_00132875.2\| COG0678: Peroxiredoxin [Haemophilus somnus 2336], gi\|170718219\|ref\|YP... gi\|23467482 - gi\|23467482\|ref\|ZP_00123063.1\| COG0678: Peroxiredoxin [Haemophilus somnus 129PT]	184.0	[0..1]	[243..1]

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Predicted Domain #1

Region A:
Residues: [1-244]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKDMTGQK VPNVTFHTRQ GDAWVDVTTS ELFDNKTVVV FSLPGAFTPT CSSTHLPRYN  60
   61 ELACEFKAAG VDSILCVSVN DTFVMNAWKA DQESENVMVI PDGNGEFTEG MGMLVGKEDL 120
  121 GFGNRSWRYS MLVKNGVVEK MFVEPQEPGD PFKVSDADTM MKYLVAGWQA KESVSIITKP 180
  181 GCPFCAKAKE TLKAKGYAFE EIVLGRDAST ISVRAITGKT AVPQVFIGGK HIGGSDELTA 240
  241 YFAK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.30103
Match:	1nm3A
Description:	C-terminal, Grx domain of Hybrid-Prx5; N-terminal, Prx domain of Hybrid-Prx5
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
antioxidant activity	3.66884588063322	bayes_pls_golite062009
peroxidase activity	3.43831566988273	bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor	3.43831566988273	bayes_pls_golite062009
glutathione peroxidase activity	2.56524997297011	bayes_pls_golite062009
peroxiredoxin activity	2.12777217096121	bayes_pls_golite062009
thioredoxin peroxidase activity	1.96134566495756	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	1.8187537496904	bayes_pls_golite062009
protein disulfide oxidoreductase activity	1.47769936616412	bayes_pls_golite062009
disulfide oxidoreductase activity	1.32811008894503	bayes_pls_golite062009
binding	1.25802922431343	bayes_pls_golite062009
selenium binding	1.1082524159827	bayes_pls_golite062009
catalytic activity	0.672192331361968	bayes_pls_golite062009
transcription regulator activity	0.52671047749426	bayes_pls_golite062009
protein binding	0.134341907247724	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: