YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|33237725, gi\|...
Organism:	Prochlorococcus marinus subsp. marinus str. CCMP1375
Length:	418 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|33237725, gi|....

Description	E-value	Query Range	Subject Range
gi\|7469455 - pir\|\|S76163 hypothetical protein - Synechocystis sp. (strain PCC 6803) Y955_SYNY3 - Uncharacterized tRNA/rRNA methyltransferase slr0955 OS=Synechocystis sp. (strain ATCC 27184 / PCC 68... Y955_SYNY3 - Uncharacterized tRNA/rRNA methyltransferase slr0955 OS=Synechocystis sp. (strain PCC 6803 / Kazusa) ...	258.0	[0..33]	[409..7]
gi\|48892550, gi\|... - gi\|71674113\|ref\|ZP_00671860.1\| RNA methyltransferase TrmH, group 3 [Trichodesmium erythraeum IMS101]...	257.0	[0..116]	[396..6]
gi\|33862923, gi\|... - gi\|33862923\|ref\|NP_894483.1\| tRNA/rRNA methyltransferase (SpoU):RNA methyltransferase TrmH... [Proch...	251.0	[0..33]	[407..60]
gi\|75910610, gi\|... - gi\|75910610\|ref\|YP_324906.1\| RNA methyltransferase TrmH, group 3 [Anabaena variabilis ATCC 29413], g...	249.0	[0..85]	[399..3]
gi\|106895728, gi... - gi\|158319524\|ref\|YP_001512031.1\| RNA methyltransferase [Alkaliphilus oremlandii OhILAs], gi\|15813972...	248.0	[0..148]	[391..1]
gi\|25316695 - pir\|\|A83664 tRNA/rRNA methyltransferase BH0113 [imported] - Bacillus halodurans (strain C-125) gi\|15612676, gi\|... - gi\|15612676\|ref\|NP_240979.1\| tRNA/rRNA methyltransferase [Bacillus halodurans C-125], gi\|10172725\|db...	248.0	[0..148]	[392..1]
gi\|48859457, gi\|... - gi\|67875040\|ref\|ZP_00504559.1\| RNA methyltransferase TrmH, group 3 [Clostridium thermocellum ATCC 27... gi\|196198671, gi... - gi\|196251913\|ref\|ZP_03150578.1\| RNA methyltransferase, TrmH family, group 3 [Clostridium thermocellu...	247.0	[0..116]	[393..1]
gi\|25325048 - pir\|\|AD1951 tRNA/rRNA methyltransferase [imported] - Nostoc sp. (strain PCC 7120) gi\|17130505, gi\|... - gi\|17228654\|ref\|NP_485202.1\| tRNA/rRNA methyltransferase [Nostoc sp. PCC 7120], gi\|17130505\|dbj\|BAB7...	247.0	[0..102]	[399..33]
gi\|206732774, gi... - gi\|206972200\|ref\|ZP_03233147.1\| RNA methyltransferase, TrmH family, group 3 [Bacillus cereus AH1134]... gi\|218160251, gi... - gi\|218232294\|ref\|YP_002364941.1\| RNA methyltransferase, TrmH family, group 3 [Bacillus cereus B4264]... gi\|30018362, gi\|... - gi\|30018362\|ref\|NP_829993.1\| 23S rRNA methyltransferase [Bacillus cereus ATCC 14579], gi\|29893902\|gb...	241.0	[0..148]	[395..1]
gi\|20808679 - gi\|20808679\|ref\|NP_623850.1\| rRNA methylase [Thermoanaerobacter tengcongensis MB4] gi\|20517315, gi\|... - gi\|20808679\|ref\|NP_623850.1\| rRNA methylase [Thermoanaerobacter tengcongensis MB4], gi\|20517315\|gb\|A...	240.0	[0..147]	[395..1]

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Predicted Domain #1

Region A:
Residues: [1-143]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSNDRRGGN FSRDFSSKER KNNKRGSSAS MRWKKGNKSE WNQSDHKKDS PYRRDTEKVN  60
   61 FDRGNQKKRN FDNARDSSAS NKASFNSKRA WRSINSEETQ NRSSSNKRQP NLVQSRRFTS 120
  121 FSRNNQNDFS QSTQEIEKPK QNF

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [144-418]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VFESESNDIF WGRHSTQAIL ESGRAIHRIW CTSEIRSSPR FFQLLKDAKA LGVLVEEVSW  60
   61 ARLGHVTTGG VHQGIALQTA ASETFDLKTL IEGCQSIDES PVLIALDGLT DPQNLGAIVR 120
  121 SAEALGAHGL ILPQRRSAGL TGSVAKVAAG ALEHLPVARV VNLNRSLEEL KKSGYTIIGL 180
  181 AGEGDKTINE ITFDGPLVLA IGSEEKGLSL LTRRHCDFLV KIPLRGVTTS LNASVATSVV 240
  241 LYEVARQGWM KGIAGQDPSP KLVRAKLETK PFQTN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.69897
Match:	1gz0A
Description:	RlmB, C-terminal domain; RlmB, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA methyltransferase activity	4.23455016472464	bayes_pls_golite062009
methyltransferase activity	3.59960278169345	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	3.51722801996622	bayes_pls_golite062009
rRNA methyltransferase activity	3.14976989427746	bayes_pls_golite062009
RNA binding	2.61675538965988	bayes_pls_golite062009
tRNA methyltransferase activity	2.33123191403389	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	2.23755555119187	bayes_pls_golite062009
tRNA (guanine) methyltransferase activity	2.14623472760939	bayes_pls_golite062009
nucleic acid binding	1.81000672982144	bayes_pls_golite062009
transferase activity	1.63934797352054	bayes_pls_golite062009
binding	1.31970199852267	bayes_pls_golite062009
structural constituent of ribosome	1.0137045454994	bayes_pls_golite062009
N-methyltransferase activity	0.736216022000293	bayes_pls_golite062009
structural molecule activity	0.694233763389628	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	0.319046095835882	bayes_pls_golite062009
catalytic activity	0.264002643439785	bayes_pls_golite062009
	0.16936231012632	bayes_pls_golite062009
snoRNA binding	0.155192244522672	bayes_pls_golite062009
protein binding	0.131685221037103	bayes_pls_golite062009
rRNA (guanine-N1-)-methyltransferase activity	6.26422903788337E-4	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: