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View Structure Prediction Details

Protein: MED25_ARATH
Organism: Arabidopsis thaliana
Length: 836 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MED25_ARATH.

Description E-value Query
Range
Subject
Range
gi|73979823 - gi|73979823|ref|XP_849291.1| PREDICTED: similar to Intersectin 2 (SH3 domain-containing protein 1B) ...
186.0 [0..376] [835..90]
gi|76630087 - gi|76630087|ref|XP_868972.1| PREDICTED: similar to Intersectin 2 (SH3 domain-containing protein 1B) ...
185.0 [0..376] [835..91]
gi|114576426 - gi|114576426|ref|XP_001144557.1| PREDICTED: intersectin 2 isoform 1 [Pan troglodytes]
181.0 [0..376] [835..90]
gi|109479040 - gi|109479040|ref|XP_001067202.1| PREDICTED: similar to SH3 domain protein 1B isoform 2 [Rattus norve...
180.0 [0..376] [835..90]

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Predicted Domain #1
Region A:
Residues: [1-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSEVKQLIV VAEGTAALGP YWQTIVSDYL EKIIRSFCGS ELNGERNPVS TVELSLVIFN  60
   61 SHGSYCACLV QRSGWTRDVD IFLHWLSSIQ FGGGGFNEVA TAEGLAEALM MFSPPSGQAQ 120
  121 PSNDLKRHCI LITASNPHIL PTPVYRPRLQ NVERNENGDA QAESRLSDAE TVASYFAKCS 180
  181 VSLSVVCPKQ LPTIRALYNA GKPNQQ

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [207-442]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SADLSIDTAK NTFYLVLISE NFVEACAALS HSATNLPQTQ SPVKVDRATV APSIPVTGQP  60
   61 PAPVSSANGP IQNRQPVSVG PVPTATVKVE PSTVTSMAPV PSFPHIPAVA RPATQAIPSI 120
  121 QTSSASPVSQ DMVSNAENAP DIKPVVVSGM TPPLRTGPPG GANVNLLNNL SQVRQVMSSA 180
  181 ALAGAASSVG QSAVAMHMSN MISTGMATSL PPSQTVFSTG QQGITSMAGS GALMGS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.69897
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [443-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AQTGQSPGPN NAFSPQTTSN VASNLGVSQP MQGMNQGSHS GAMMQGGISM NQNMMSGLGQ  60
   61 GNVSSGTGGM MPTPGVGQQA QSGIQQLGGS NSSAPNMQLS QPSSGAMQTS QS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [555-836]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KYVKVWEGNL SGQRQGQPVL ITRLEGYRSA SASDSLAANW PPTMQIVRLI SQDHMNNKQY  60
   61 VGKADFLVFR AMSQHGFLGQ LQDKKLCAVI QLPSQTLLLS VSDKACRLIG MLFPGDMVVF 120
  121 KPQIPNQQQQ QQQQLHQQQQ QQQQIQQQQQ QQQHLQQQQM PQLQQQQQQH QQQQQQQHQL 180
  181 SQLQHHQQQQ QQQQQQQQQH QLTQLQHHHQ QQQQASPLNQ MQQQTSPLNQ MQQQTSPLNQ 240
  241 MQQQQQPQQM VMGGQAFAQA PGRSQQGGGG GQPNMPGAGF MG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 14.0
Match: 1i84S
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

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