YRC Public Data Repository - Protein Structure Prediction

Protein:	HMP_DEIRA
Organism:	Deinococcus radiodurans R1
Length:	403 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HMP_DEIRA.

Description	E-value	Query Range	Subject Range
HMP_BACHD - Flavohemoprotein OS=Bacillus halodurans GN=hmp PE=3 SV=1 HMP_BACHD - Flavohemoprotein OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-...	5.0E-69	[2..398]	[6..409]
gi\|52002629, gi\|... - gi\|52784778\|ref\|YP_090607.1\| Hmp [Bacillus licheniformis ATCC 14580], gi\|52347280\|gb\|AAU39914.1\| Hmp...	5.0E-69	[1..396]	[1..399]
gi\|113724938, gi... - gi\|150377361\|ref\|YP_001313956.1\| nitric oxide dioxygenase [Sinorhizobium medicae WSM419], gi\|1500319...	5.0E-67	[1..393]	[1..398]
gi\|56908365, gi\|... - gi\|56962130\|ref\|YP_173853.1\| nitric oxide dioxygenase [Bacillus clausii KSM-K16], gi\|56908365\|dbj\|BA...	5.0E-67	[1..398]	[5..409]
HMP_PSEPK - Flavohemoprotein OS=Pseudomonas putida (strain KT2440) GN=hmp PE=3 SV=1	7.0E-67	[1..397]	[1..391]
HMP_RHIME - Flavohemoprotein OS=Rhizobium meliloti GN=hmp PE=3 SV=2 HMP_RHIME - Flavohemoprotein OS=Rhizobium meliloti (strain 1021) GN=hmp PE=3 SV=2	9.0E-67	[1..393]	[1..398]
HMP_BACC1 - Flavohemoprotein OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=hmp PE=3 SV=1	1.0E-66	[1..398]	[1..402]
gi\|47554187, gi\|... - gi\|47569116\|ref\|ZP_00239804.1\| flavohemoprotein [Bacillus cereus G9241], gi\|47554187\|gb\|EAL12550.1\| ...	3.0E-66	[1..398]	[1..402]
tr\|E4R4H4\|E4R4H4... - Flavohemoprotein OS=Pseudomonas putida (strain BIRD-1) GN=PPUBIRD1_0854 PE=3 SV=1 tr\|I7C1Y3\|I7C1Y3... - Flavohemoprotein OS=Pseudomonas putida (strain DOT-T1E) GN=hmpA PE=3 SV=1 gi\|82714800, gi\|... - gi\|82738110\|ref\|ZP_00900949.1\| flavohemoprotein [Pseudomonas putida F1], gi\|82714800\|gb\|EAP49875.1\| ...	4.0E-66	[1..397]	[1..391]
HMP_BACHK - Flavohemoprotein OS=Bacillus thuringiensis subsp. konkukian GN=hmp PE=3 SV=1 gi\|228845573, gi... - gi\|228914120\|ref\|ZP_04077740.1\| Flavohemoprotein [Bacillus thuringiensis serovar pulsiensis BGSC 4CC... gi\|228833165, gi... - gi\|228926577\|ref\|ZP_04089648.1\| Flavohemoprotein [Bacillus thuringiensis serovar pondicheriensis BGS... HMP_BACHK - Flavohemoprotein OS=Bacillus thuringiensis subsp. konkukian (strain 97-27) GN=hmp PE=3 SV=1	1.0E-65	[1..398]	[1..402]

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Predicted Domain #1

Region A:
Residues: [1-403]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLTPEQKAIV KATVPALEAH GETITRTFYA SMFAAHPELL NIFNPANQQT GKQARSLAAS  60
   61 VLAYAAHIDH PEALGGMVGR IAHKHVSLEV LPEHYPIVGQ YLLGAIAGVL GDAAKPEILD 120
  121 AWAAAYGELA DLMIGIEKGM YDAGAGQPGG WRDFRPFRVA RKVAESRVIT SFVLEPVGGG 180
  181 ALPAYQPGQY LSLKVKVPGQ ERWQIRQYSL SDAPSPDHYR ISVKREGGGL VSEYLHGAVQ 240
  241 EGDELLVHVP AGDFVLQQSE RPVVLISAGV GITPMLAMVQ TLAQAGSQRP VTFIHAAQNG 300
  301 SVHAFRDDVA RLTHEYPHFR KVVFYDEAGP DDQLGTHHDV AGRLSLDAVR GALPAGEAEF 360
  361 YYCGPAGFAG AVEAILDDLQ VPAERRFTET FGPSQSFAPV ILG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.522879
Match:	1cqxA
Description:	Flavohemoglobin, N-terminal domain; Flavohemoglobin, central domain; Flavohemoglobin, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxygen transporter activity	7.81281381234264	bayes_pls_golite062009
oxygen binding	3.78522064312431	bayes_pls_golite062009
hemoglobin binding	3.17505496298935	bayes_pls_golite062009
transporter activity	2.77225108027137	bayes_pls_golite062009
substrate-specific transporter activity	2.44807175467553	bayes_pls_golite062009
catalytic activity	2.05427820269334	bayes_pls_golite062009
binding	1.4855235778453	bayes_pls_golite062009
hemoglobin alpha binding	1.07662870695556	bayes_pls_golite062009
nitric-oxide synthase activity	0.943011064240739	bayes_pls_golite062009
transferase activity	0.708491789248912	bayes_pls_golite062009
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen	0.426427097788618	bayes_pls_golite062009
riboflavin synthase activity	0.366634814975673	bayes_pls_golite062009
protein binding	0.195144485644841	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: