YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|11351923
Organism:	Pseudomonas aeruginosa
Length:	289 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|11351923.

Description	E-value	Query Range	Subject Range
gi\|71675440, gi\|... - gi\|71675440\|ref\|ZP_00673185.1\| TPR repeat:Sel1-like repeat [Trichodesmium erythraeum IMS101], gi\|716...	7.0E-41	[88..285]	[1132..1327]
gi\|46119251, gi\|... - gi\|67923685\|ref\|ZP_00517153.1\| TPR repeat:TPR repeat [Crocosphaera watsonii WH 8501], gi\|67854485\|gb...	7.0E-40	[8..284]	[251..507]
gi\|72397563, gi\|... - gi\|73670401\|ref\|YP_306416.1\| hypothetical protein Mbar_A2941 [Methanosarcina barkeri str. Fusaro], g...	3.0E-39	[80..283]	[354..555]
gi\|91179546, gi\|... - gi\|91222647\|ref\|ZP_01258022.1\| TPR repeat [Psychroflexus torquis ATCC 700755], gi\|91179546\|gb\|EAS671...	5.0E-38	[88..285]	[31..226]
gi\|40063048 - gi\|40063048\|gb\|AAR37904.1\| TPR domain protein [uncultured marine bacterium 560]	1.0E-37	[88..285]	[44..239]
gi\|116066974, gi... - gi\|116075659\|ref\|ZP_01472918.1\| TPR repeat [Synechococcus sp. RS9916], gi\|116066974\|gb\|EAU72729.1\| T...	2.0E-37	[83..284]	[63..262]
gi\|40063716 - gi\|40063716\|gb\|AAR38497.1\| TPR repeat protein [uncultured marine bacterium 583]	2.0E-37	[92..285]	[48..239]
gi\|72002781, gi\|... - gi\|72382931\|ref\|YP_292286.1\| TPR repeat-containing protein [Prochlorococcus marinus str. NATL2A], gi...	3.0E-37	[88..285]	[163..358]

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Predicted Domain #1

Region A:
Residues: [1-75]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSDTPYIFDV TGANFEQLVI ENSFHKPVLV DFWADWCAPC KALMPLLAQI AESYQGELLL  60
   61 AKVNCDVEQD IVMRF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10.522879
Match:	2fd3A
Description:	Crystal Structure of Thioredoxin Mutant P34H
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [76-289]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GIRSLPTVVL FKDGQPVDGF AGAQPESQIR ALLEPHVKAP ALPDEDPLEV AQALFAEGRI  60
   61 GDAEATLKAL LAENNENAAA LILYARCLAE RGELEEAQAI LDAVKSDEHK QALAGARAQL 120
  121 TFLRQAADLP DSAELKSRLA ADAGDDEAAY QLAVQQLARQ QYEAALDGLL KLFLRNRGYQ 180
  181 DDLPRKTLVQ VFDLLGNDHP LVTAYRRKLY QALY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	30.522879
Match:	1w3bA
Description:	The superhelical TPR domain of O-linked GlcNAc transferase reveals structural similarities to importin alpha.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	2.71974493738804	bayes_pls_golite062009
protein binding	1.6279032205159	bayes_pls_golite062009
soluble NSF attachment protein activity	1.23402264298006	bayes_pls_golite062009
transcription regulator activity	1.02070055347338	bayes_pls_golite062009
nucleic acid binding	1.01193875360949	bayes_pls_golite062009
DNA binding	0.80346414607277	bayes_pls_golite062009
hydrolase activity	0.722744548996965	bayes_pls_golite062009
signal sequence binding	0.49295886046194	bayes_pls_golite062009
transcription factor activity	0.134824164012026	bayes_pls_golite062009
peroxisome targeting sequence binding	0.0468412220974996	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: